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Internalization of Glimepiride and Glibenclamide in the Pancreatic B-cell
- Source :
- Acta Diabetologica : an international journal devoted to the study of clinical and experimental diabetes and metabolism, Vol. 29, no. 2, p. 113-114 (1992)
- Publication Year :
- 1992
-
Abstract
- When rat pancreatic islets were exposed for 30 min at 37-degrees-C to tritiated glibenclamide (2.5 muM) or glimepiride (1.5 muM), internalization of these hypoglycaemic sulphonylureas in B and non-B cells was observed by autoradiography. In the B cell, the autoradiographic grains were often associated with secretory granules.
Details
- Database :
- OAIster
- Journal :
- Acta Diabetologica : an international journal devoted to the study of clinical and experimental diabetes and metabolism, Vol. 29, no. 2, p. 113-114 (1992)
- Notes :
- English
- Publication Type :
- Electronic Resource
- Accession number :
- edsoai.on1130559016
- Document Type :
- Electronic Resource