Back to Search Start Over

Synthesis, Characterization and Antitumor Activity of Some New Oganotellurium Compounds Containing Azomethine Group, Part One

Authors :
Al-Asadi, Rafid H.
Fahad, Tarik A.
Saeed, Bahjat A.
Al-Masoudi, Wasfi A.
Al-Asadi, Rafid H.
Fahad, Tarik A.
Saeed, Bahjat A.
Al-Masoudi, Wasfi A.
Source :
JOURNAL OF ADVANCES IN CHEMISTRY; Vol. 8 No. 1 (2014); 1464-1471; 2321-807X
Publication Year :
2016

Abstract

New tellurated schiff bases were synthesized by the reaction of the corresponding mercurated Schiff  bases compounds A1-A3 with tellurium tetrabromide in 1:1 mole ratio and  that  gave organyltellurium tribromides  A4-A6.  On the other hand, when mercurated schiff bases and tellurium tetrabromide brought  together in 2:1 mole ratio gave diorganyltellurium dibromides compounds A10-A12 followed by reduction with hydrazine hydrate gave new diorganyl tellurides A13-A15. Reduction of compounds A4-A6 by hydrazine hydrate gave new ditellurides A7-A9.  All compounds were characterized by elemental analysis, IR, 1H , 13C NMR, HSQC-NMR and mass spectra. Invitro anti-tumor bioactivity of some compounds were tested.Â

Details

Database :
OAIster
Journal :
JOURNAL OF ADVANCES IN CHEMISTRY; Vol. 8 No. 1 (2014); 1464-1471; 2321-807X
Notes :
application/pdf, English
Publication Type :
Electronic Resource
Accession number :
edsoai.on1134120763
Document Type :
Electronic Resource