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Genome-wide meta-analysis identifies new susceptibility loci for migraine

Authors :: Anttila, V.
Winsvold, B.S.
Gormley, P.
Kurth, T.
Bettella, F.
McMahon, G.
Kallela, M.
Malik, R.
de Vries, B.
Terwindt, G.
Medland, S.E.
Todt, U.
McArdle, W.L.
Quaye, L.
Koiranen, M.
Ikram, M.A.
Lehtimäki, T.
Stam, A.H.
Ligthart, L.
Wedenoja, J.
Dunham, I.
Neale, B. M.
Palta, P.
Hamalainen, E.
Schürks, M.
Rose, L.M.
Buring, J.E.
Ridker, P.M.
Steinberg, S.
Stefansson, H.
Jakobsson, F.
Lawlor, D.A.
Evans, D.M.
Ring, S.M.
Färkkilä, M.
Artto, V.
Kaunisto, M.A.
Freilinger, T.
Schoenen, J.
Frants, R.R.
Pelzer, N.
Weller, C.M.
Zielman, R.
Heath, A.C.
Madden, P.A.F.
Montgomery, G.W.
Martin, N.G.
Borck, G.
Göbel, H.
Heinze, A.
Heinze-Kuhn, K.
Williams, F.M.
Hartikainen, A.-L.
Pouta, A.
van den Ende, J..
Uitterlinden, A.G.
Hofman, A.
Amin, N.
Hottenga, J.J.
Vink, J.M.
Heikkilä, K.
Alexander, M.
Muller-Myhsok, B.
Schreiber, S
Meitinger, T.
Wichmann, H. E.
Aromaa, A.
Eriksson, J.G.
Traynor, B.J.
Trabzuni, D.
Rossin, E.
Lage, K.
Jacobs, S.B.
Gibbs, J.R.
Birney, E.
Kaprio, J.
Penninx, B.W.J.H.
Boomsma, D.I.
van Duijn, C.M.
Raitakari, O.
Jarvelin, M.-R.
Zwart, J.A.
Cherkas, L.
Strachan, D.P.
Kubisch, C.
Ferrari, M.D.
van den Maagdenberg, A.M.J.M.
Dichgans, M.
Wessman, M.
Smith, G.D.
Stefansson, K.
Daly, M.J.
Nyholt, DR
Chasman, D.I.
Palotie, A.
Anttila, V.
Winsvold, B.S.
Gormley, P.
Kurth, T.
Bettella, F.
McMahon, G.
Kallela, M.
Malik, R.
de Vries, B.
Terwindt, G.
Medland, S.E.
Todt, U.
McArdle, W.L.
Quaye, L.
Koiranen, M.
Ikram, M.A.
Lehtimäki, T.
Stam, A.H.
Ligthart, L.
Wedenoja, J.
Dunham, I.
Neale, B. M.
Palta, P.
Hamalainen, E.
Schürks, M.
Rose, L.M.
Buring, J.E.
Ridker, P.M.
Steinberg, S.
Stefansson, H.
Jakobsson, F.
Lawlor, D.A.
Evans, D.M.
Ring, S.M.
Färkkilä, M.
Artto, V.
Kaunisto, M.A.
Freilinger, T.
Schoenen, J.
Frants, R.R.
Pelzer, N.
Weller, C.M.
Zielman, R.
Heath, A.C.
Madden, P.A.F.
Montgomery, G.W.
Martin, N.G.
Borck, G.
Göbel, H.
Heinze, A.
Heinze-Kuhn, K.
Williams, F.M.
Hartikainen, A.-L.
Pouta, A.
van den Ende, J..
Uitterlinden, A.G.
Hofman, A.
Amin, N.
Hottenga, J.J.
Vink, J.M.
Heikkilä, K.
Alexander, M.
Muller-Myhsok, B.
Schreiber, S
Meitinger, T.
Wichmann, H. E.
Aromaa, A.
Eriksson, J.G.
Traynor, B.J.
Trabzuni, D.
Rossin, E.
Lage, K.
Jacobs, S.B.
Gibbs, J.R.
Birney, E.
Kaprio, J.
Penninx, B.W.J.H.
Boomsma, D.I.
van Duijn, C.M.
Raitakari, O.
Jarvelin, M.-R.
Zwart, J.A.
Cherkas, L.
Strachan, D.P.
Kubisch, C.
Ferrari, M.D.
van den Maagdenberg, A.M.J.M.
Dichgans, M.
Wessman, M.
Smith, G.D.
Stefansson, K.
Daly, M.J.
Nyholt, DR
Chasman, D.I.
Palotie, A.
Source :: Vrije Universiteit Amsterdam Repository
Publication Year :: 2013
Abstract: Migraine is the most common brain disorder, affecting approximately 14% of the adult population, but its molecular mechanisms are poorly understood. We report the results of a meta-analysis across 29 genome-wide association studies, including a total of 23,285 individuals with migraine (cases) and 95,425 population-matched controls. We identified 12 loci associated with migraine susceptibility (P < 5 × 10

Details

Database :: OAIster
Journal :: Vrije Universiteit Amsterdam Repository
Notes :: Nature Genetics vol.45 (2013) nr.8 p.912-917 [ISSN 1061-4036], English
Publication Type :: Electronic Resource
Accession number :: edsoai.on1136585780
Document Type :: Electronic Resource
Full Text :: https://doi.org/10.1038.ng.2676