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Velocity Transfer Function In The Right Pulmonary Artery And Impaired Cardiopulmonary Reserve In COPD

Velocity Transfer Function In The Right Pulmonary Artery And Impaired Cardiopulmonary Reserve In COPD

Authors :
Sharifov,Oleg F
Denney Jr,Thomas S
Wells,J. Michael
Payne,Gregory A
Gulati,Swati
Gupta,Himanshu
Dransfield,Mark T
Lloyd,Steven G
Sharifov,Oleg F
Denney Jr,Thomas S
Wells,J. Michael
Payne,Gregory A
Gulati,Swati
Gupta,Himanshu
Dransfield,Mark T
Lloyd,Steven G
Publication Year :
2019

Abstract

Oleg F Sharifov,1 Thomas S Denney Jr,2 J Michael Wells,1,3,4 Gregory A Payne,1,4 Swati Gulati,1,3 Himanshu Gupta,5 Mark T Dransfield,1,3,4 Steven G Lloyd1,4 1Department of Medicine, University of Alabama at Birmingham (UAB), Birmingham, AL, USA; 2Department of Electrical and Computer Engineering, Auburn University, Auburn, AL, USA; 3UAB Lung Health Center, Birmingham, AL, USA; 4Birmingham VA Medical Center, Birmingham, AL, USA; 5Advanced Cardiovascular Imaging, Valley Medical Group, Paramus, NJ, USACorrespondence: Steven G LloydDepartment of Medicine, University of Alabama at Birmingham, 1808 7th Avenue South, BDB 201, Birmingham, AL 35294-0012, USATel +1 205 934 9736Fax +1 205 934 9730Email slloyd@uabmc.eduPulmonary hypertension (PH) is an important prognostic indicator in patients with chronic obstructive pulmonary disease (COPD); however, PH in these patients is typically mild-to-moderate severity and invasive testing is not typically utilized.1 Though echocardiography can be used to screen for PH, it has limited accuracy in measuring pulmonary artery (PA) pressure and often hindered by window limitations in COPD patients.2 Cardiovascular magnetic resonance (CMR) does not have window limitations and can accurately evaluate the right ventricular (RV) and PA function. Therefore, there is a growing interest in the use of CMR for the diagnosis and management of PH, including patients with lung diseases. Recently, we have validated a novel non-invasive CMR-derived parameter that, similar to impedance, reflects pulsatile and resistive properties of the PA.3 This approach relies on the principle that compliant PA vessel walls cause changes in the velocity profile as it travels through the PA over the cardiac cycle. The frequency-dependent relationship between the input and output velocity profiles is described by a velocity transfer function (VTF), which is the relationship between the frequency spectra of input and output velocity.3 In suspected PH patients who underwe

Details

Database :
OAIster
Notes :
text/html, English
Publication Type :
Electronic Resource
Accession number :
edsoai.on1141817159
Document Type :
Electronic Resource