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Distribution patterns of tau pathology in progressive supranuclear palsy

Authors :
Kovacs, G.G. (Gabor)
Lukic, M.J. (Milica Jecmenica)
Irwin, D.J. (David J.)
Arzberger, T. (T.)
Respondek, G. (Gesine)
Lee, E.B. (Edward B.)
Coughlin, D. (David)
Giese, A. (Armin)
Grossman, M. (Murray)
Kurz, C. (Carolin)
McMillan, C.T. (Corey T.)
Gelpi, E. (Ellen)
Compta, Y. (Yaroslau)
Swieten, J.C. (John) van
Laat, L.D. (Laura Donker)
Troakes, C. (Claire)
Al-Sarraj, S. (Safa)
Robinson, J.L. (John L.)
Roeber, S. (Sigrun)
Xie, S.X. (Sharon X.)
Lee, V.M.Y. (Virginia)
Trojanowski, J.Q. (John Q.)
Hoglinger, G. (Gunter)
Kovacs, G.G. (Gabor)
Lukic, M.J. (Milica Jecmenica)
Irwin, D.J. (David J.)
Arzberger, T. (T.)
Respondek, G. (Gesine)
Lee, E.B. (Edward B.)
Coughlin, D. (David)
Giese, A. (Armin)
Grossman, M. (Murray)
Kurz, C. (Carolin)
McMillan, C.T. (Corey T.)
Gelpi, E. (Ellen)
Compta, Y. (Yaroslau)
Swieten, J.C. (John) van
Laat, L.D. (Laura Donker)
Troakes, C. (Claire)
Al-Sarraj, S. (Safa)
Robinson, J.L. (John L.)
Roeber, S. (Sigrun)
Xie, S.X. (Sharon X.)
Lee, V.M.Y. (Virginia)
Trojanowski, J.Q. (John Q.)
Hoglinger, G. (Gunter)
Publication Year :
2020

Abstract

Progressive supranuclear palsy (PSP) is a 4R-tauopathy predominated by subcortical pathology in neurons, astrocytes, and oligodendroglia associated with various clinical phenotypes. In the present international study, we addressed the question of whether or not sequential distribution patterns can be recognized for PSP pathology. We evaluated heat maps and distribution patterns of neuronal, astroglial, and oligodendroglial tau pathologies and their combinations in different clinical subtypes of PSP in postmortem brains. We

Details

Database :
OAIster
Notes :
application/pdf, Acta Neuropathologica, English
Publication Type :
Electronic Resource
Accession number :
edsoai.on1157012242
Document Type :
Electronic Resource
Full Text :
https://doi.org/10.1007.s00401-020-02158-2