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A general strategy for obtaining biodegradable polymer shelled microbubbles as theranostic devices

Authors :
Capece, Sabrina
Chiessi, Ester
Cavalli, Roberta
Giustetto, Pierangela
Grishenkov, Dmitry
Paradossi, Gaio
Capece, Sabrina
Chiessi, Ester
Cavalli, Roberta
Giustetto, Pierangela
Grishenkov, Dmitry
Paradossi, Gaio
Publication Year :
2013

Abstract

Fabrication of multifunctional ultrasound contrast agents (UCAs) has been recently addressed by several research groups. A versatile strategy for the synthesis of UCA precursors in the form of biodegradable vesicles with a biocompatible crosslinked polymer shell is described. Upon ultrasound irradiation, acoustic droplet vaporization transforms such particles into microbubbles behaving as UCAs. This proof of concept entails the features of a potential theranostic microdevice.<br />QC 20131211<br />3 MiCRON EU FP7

Details

Database :
OAIster
Notes :
English
Publication Type :
Electronic Resource
Accession number :
edsoai.on1234997077
Document Type :
Electronic Resource
Full Text :
https://doi.org/10.1039.C3CC42037J