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Impact of chronic obstructive pulmonary disease and dyspnoea on clinical outcomes in ticagrelor treated patients undergoing percutaneous coronary intervention in the randomized GLOBAL LEADERS trial

Authors :
Tomaniak, M. (Mariusz)
Chichareon, P. (Ply)
Takahashi, K. (Kuniaki)
Kogame, N. (Norihiro)
Modolo, R. (Rodrigo)
Chang, C.C. (Chun Chin)
Spitzer, E. (Ernest)
Neumann, F.J.
Plante, S. (Sylvain)
Hernandez-Antolin, R. (Rosana)
Jambrik, Z. (Zoltan)
Gelev, V. (Valeri)
Brunel, P. (Philippe)
Konteva, M. (Mariana)
Beygui, F. (Farzin)
Morelle, J.-F. (Jean-Francois)
Filipiak, K.J. (Krzysztof J.)
Geuns, R.J.M. (Robert Jan) van
Soliman, O.I.I. (Osama Ibrahim Ibrahim)
Tijssen, J.G.P. (Jan)
Rademaker-Havinga, T.A.M. (Tessa)
Storey, D. (David)
Hamm, C. (Christian)
Steg, P.G. (Philippe Gabriel)
Windecker, S.W. (Stephan)
Onuma, Y. (Yoshinobu)
Valgimigli, M. (Marco)
Serruys, P.W.J.C. (Patrick)
Tomaniak, M. (Mariusz)
Chichareon, P. (Ply)
Takahashi, K. (Kuniaki)
Kogame, N. (Norihiro)
Modolo, R. (Rodrigo)
Chang, C.C. (Chun Chin)
Spitzer, E. (Ernest)
Neumann, F.J.
Plante, S. (Sylvain)
Hernandez-Antolin, R. (Rosana)
Jambrik, Z. (Zoltan)
Gelev, V. (Valeri)
Brunel, P. (Philippe)
Konteva, M. (Mariana)
Beygui, F. (Farzin)
Morelle, J.-F. (Jean-Francois)
Filipiak, K.J. (Krzysztof J.)
Geuns, R.J.M. (Robert Jan) van
Soliman, O.I.I. (Osama Ibrahim Ibrahim)
Tijssen, J.G.P. (Jan)
Rademaker-Havinga, T.A.M. (Tessa)
Storey, D. (David)
Hamm, C. (Christian)
Steg, P.G. (Philippe Gabriel)
Windecker, S.W. (Stephan)
Onuma, Y. (Yoshinobu)
Valgimigli, M. (Marco)
Serruys, P.W.J.C. (Patrick)
Publication Year :
2020

Abstract

AIMS: To evaluate long-term safety and efficacy of ticagrelor monotherapy in patients undergoing percutaneous coronary interventions (PCIs) in relation to chronic obstructive pulmonary disease (COPD) at baseline and the occurrence of dyspnoea reported as adverse event (AE) that may lead to treatment non-adherence. METHODS AND RESULTS: This is a non-prespecified, post hoc analysis of the randomized GLOBAL LEADERS trial (n = 15 991), comparing the experimental strategy of 23-month ticagrelor monotherapy following 1-mon

Details

Database :
OAIster
Notes :
application/pdf, European heart journal. Cardiovascular pharmacotherapy vol. 6 no. 4, pp. 222-230, English
Publication Type :
Electronic Resource
Accession number :
edsoai.on1244879376
Document Type :
Electronic Resource
Full Text :
https://doi.org/10.1093.ehjcvp.pvz052