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Chimeric camel/human heavy-chain antibodies protect against MERS-CoV infection
- Publication Year :
- 2018
-
Abstract
- Middle East respiratory syndrome coronavirus (MERS-CoV) continues to cause outbreaks in humans as a result of spillover events from dromedaries. In contrast to humans, MERS-CoV¿exposed dromedaries develop only very mild infections and exceptionally potent virus-neutralizing antibody responses. These strong antibody responses may be caused by affinity maturation as a result of repeated exposure to the virus or by the fact that dromedaries¿ apart from conventional antibodies¿have relatively unique, heavy chain¿only antibodies (HCAbs).
Details
- Database :
- OAIster
- Publication Type :
- Electronic Resource
- Accession number :
- edsoai.on1286540261
- Document Type :
- Electronic Resource