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Sequential Liver-Kidney Transplantation for Recurrent Liver Cysts Infection in a Patient With Autosomal Dominant Polycystic Kidney Disease: A Case Report.

Authors :
UCL - SSS/IREC/GAEN - Pôle d'Hépato-gastro-entérologie
UCL - (SLuc) Service de gastro-entérologie
UCL - SSS/IREC/CHEX - Pôle de chirgurgie expérimentale et transplantation
UCL - (SLuc) Service de chirurgie et transplantation abdominale
UCL - SSS/IREC/NEFR - Pôle de Néphrologie
UCL - (SLuc) Service de néphrologie
UCL - (SLuc) Service de médecine interne générale
UCL - (MGD) Service de médecine nucléaire
UCL - SSS/IREC/MIRO - Pôle d'imagerie moléculaire, radiothérapie et oncologie
UCL - SSS/IONS - Institute of NeuroScience
UCL - (SLuc) Service d'anatomie pathologique
Issa, Zaina
Ciccarelli, Olga
Devresse, Arnaud
Kanaan, Nada
Larranaga Lapique, Eva
De Greef, Julien
Lhommel, Renaud
Kerschen, Anja
Komuta, Mina
Delire, Bénédicte
Dahlqvist, Géraldine
UCL - SSS/IREC/GAEN - Pôle d'Hépato-gastro-entérologie
UCL - (SLuc) Service de gastro-entérologie
UCL - SSS/IREC/CHEX - Pôle de chirgurgie expérimentale et transplantation
UCL - (SLuc) Service de chirurgie et transplantation abdominale
UCL - SSS/IREC/NEFR - Pôle de Néphrologie
UCL - (SLuc) Service de néphrologie
UCL - (SLuc) Service de médecine interne générale
UCL - (MGD) Service de médecine nucléaire
UCL - SSS/IREC/MIRO - Pôle d'imagerie moléculaire, radiothérapie et oncologie
UCL - SSS/IONS - Institute of NeuroScience
UCL - (SLuc) Service d'anatomie pathologique
Issa, Zaina
Ciccarelli, Olga
Devresse, Arnaud
Kanaan, Nada
Larranaga Lapique, Eva
De Greef, Julien
Lhommel, Renaud
Kerschen, Anja
Komuta, Mina
Delire, Bénédicte
Dahlqvist, Géraldine
Source :
Transplantation Proceedings, Vol. 53, no. 4, p. 1322-1326 (2021)
Publication Year :
2021

Abstract

Autosomal dominant polycystic kidney disease (ADPKD) is the most prevalent hereditary kidney disorder. Liver cysts are the most common extrarenal manifestation of the disease and usually remain asymptomatic. Liver cyst infection is rare, and its treatment is challenging. Liver transplantation (LT) is the only curative therapeutic option in symptomatic polycystic liver disease associated with ADPKD. Only a few cases of LT for recurrent liver cyst infection have been published. To our knowledge, we report the first case of sequential liver-kidney transplantation for recurrent liver cysts infection in a patient with ADPKD. A 55-year-old woman with ADPKD who had a kidney transplantation (KT) presented with multiple liver cysts infection 9 months after her KT. These episodes started after biliary tract complications due to an ampullary adenoma necessitating multiple endoscopic interventions. Her general status gradually degraded because antibiotic treatment was not effective, and she underwent LT for recurrent liver cysts infection 1 year and 9 months after her KT. LT in this setting turned out to be challenging but was possible. We think that better biliary tract workup before KT may prompt better care in these patients.

Details

Database :
OAIster
Journal :
Transplantation Proceedings, Vol. 53, no. 4, p. 1322-1326 (2021)
Notes :
English
Publication Type :
Electronic Resource
Accession number :
edsoai.on1288281820
Document Type :
Electronic Resource