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Single-molecule studies of fork dynamics in Escherichia coli DNA replication

Authors :
Tanner, Nathan A
Hamdan, Samir
Jergic, Slobodan
Loscha, Karin
Schaeffer, Patrick
Dixon, Nicholas
van Oijen, Antoine M
Tanner, Nathan A
Hamdan, Samir
Jergic, Slobodan
Loscha, Karin
Schaeffer, Patrick
Dixon, Nicholas
van Oijen, Antoine M
Source :
Nature Structural and Molecular Biology
Publication Year :
2008

Abstract

We present single-molecule studies of the Escherichia coli replication machinery. We visualize individual E. coli DNA polymerase III (Pol III) holoenzymes engaging in primer extension and leading-strand synthesis. When coupled to the replicative helicase

Details

Database :
OAIster
Journal :
Nature Structural and Molecular Biology
Publication Type :
Electronic Resource
Accession number :
edsoai.on1291775119
Document Type :
Electronic Resource