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Dispersed phantom scatterer technique reveals subtle differences in substrate recognition by phospholipase D inactive mutants

Authors :
Morasso, C
Bellini, T
Monti, D
Bassi, M
Prosperi, D
Riva, S
Riva, S.
PROSPERI, DAVIDE
Morasso, C
Bellini, T
Monti, D
Bassi, M
Prosperi, D
Riva, S
Riva, S.
PROSPERI, DAVIDE
Publication Year :
2009

Abstract

An elastic light scattering based method, making use of phantom nanoparticles as substrate organizer, allowed the quantitative evaluation of the molecular recognition events between a series of inactivated mutants of phospholipase D and lysophosphatidylcholine, highlighting remarkable binding capability modifications by single amino acid substitutions.

Details

Database :
OAIster
Notes :
English
Publication Type :
Electronic Resource
Accession number :
edsoai.on1308893854
Document Type :
Electronic Resource