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The Family of LPS Signal Transducers Increases: the Arrival of Chanzymes

Authors :
Granucci, F
Granucci, F
Publication Year :
2018

Abstract

After LPS recognition, the MyD88-dependent and the TRIF-dependent pathways are consecutively activated in macrophages. Schappe et al. (2018) show that the chanzyme TRPM7 is required for an efficient LPS receptor complex endosomal relocation and the activation of the TRIF pathway.

Details

Database :
OAIster
Notes :
English
Publication Type :
Electronic Resource
Accession number :
edsoai.on1308923174
Document Type :
Electronic Resource