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Long-term treatment with losartan versus atenolol improves insulin sensitivity in hypertension: ICARUS, a LIFE substudy

Authors :
Olsen, Michael H
Fossum, Eigil
Høieggen, Aud
Wachtell, Kristian
Hjerkinn, Elsa
Nesbitt, Shawna D
Andersen, Ulrik B
Phillips, Robert A
Gaboury, Cynthia L
Ibsen, Hans
Kjeldsen, Sverre E
Julius, Stevo
Olsen, Michael H
Fossum, Eigil
Høieggen, Aud
Wachtell, Kristian
Hjerkinn, Elsa
Nesbitt, Shawna D
Andersen, Ulrik B
Phillips, Robert A
Gaboury, Cynthia L
Ibsen, Hans
Kjeldsen, Sverre E
Julius, Stevo
Source :
Olsen , M H , Fossum , E , Høieggen , A , Wachtell , K , Hjerkinn , E , Nesbitt , S D , Andersen , U B , Phillips , R A , Gaboury , C L , Ibsen , H , Kjeldsen , S E & Julius , S 2005 , ' Long-term treatment with losartan versus atenolol improves insulin sensitivity in hypertension: ICARUS, a LIFE substudy ' , Journal of Hypertension , vol. 23 , no. 4 , pp. 891-8 .
Publication Year :
2005

Abstract

Hypertension and insulin resistance might be associated through peripheral vascular hypertrophy/rarefaction which compromises skeletal muscle blood flow and decreases glucose uptake, inducing insulin resistance. We hypothesized that treatment with losartan as compared to atenolol would improve insulin sensitivity through regression of peripheral vascular hypertrophy/rarefaction.

Details

Database :
OAIster
Journal :
Olsen , M H , Fossum , E , Høieggen , A , Wachtell , K , Hjerkinn , E , Nesbitt , S D , Andersen , U B , Phillips , R A , Gaboury , C L , Ibsen , H , Kjeldsen , S E & Julius , S 2005 , ' Long-term treatment with losartan versus atenolol improves insulin sensitivity in hypertension: ICARUS, a LIFE substudy ' , Journal of Hypertension , vol. 23 , no. 4 , pp. 891-8 .
Notes :
English
Publication Type :
Electronic Resource
Accession number :
edsoai.on1314042195
Document Type :
Electronic Resource