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Efficacy of combined CDK9/13ET inhibition in preclinical models of MLL-rearranged acute leukemia
- Publication Year :
- 2020
-
Abstract
- Cyclin-dependent kinase 9 and bromodomain and extraterminal inhibitors are synergistic in MLL-rearranged leukemia. Multiple AML driver genes are downregulated by the combined therapy suggesting broad applicability for this subtype.
Details
- Database :
- OAIster
- Publication Type :
- Electronic Resource
- Accession number :
- edsoai.on1315671726
- Document Type :
- Electronic Resource