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[Multi-facetted clinical presentation of thrombotic thrombocytopenic purpura]

Authors :
Niemann, C.U.
Jurlander, J.
Daugaard, G.
Friis-Hansen, L.
Niemann, C.U.
Jurlander, J.
Daugaard, G.
Friis-Hansen, L.
Source :
Niemann , C U , Jurlander , J , Daugaard , G & Friis-Hansen , L 2009 , ' [Multi-facetted clinical presentation of thrombotic thrombocytopenic purpura] ' , Ugeskrift for læger , bind 171 , nr. 5 , s. 340-342 .
Publication Year :
2009

Abstract

Thrombotic thrombocytopenic purpura (TTP) is a thrombotic microangiopathic disease. TTP is due to reduced activity of the von Willebrand factor which cleaves ADAMTS13. The disease is characterized by thrombocytopenia (<20 billion/l) intravascular Coombs-negative haemolysis and schistocytes in blood smears. Determination of the ADAMTS13-activity is now becoming available as a routine analysis. We present two cases that illustrate the multi-facetted clinical presentation under which TTP occurs. The importance of access to ADAMTS13 measurements is stressed Udgivelsesdato: 2009/1/26

Details

Database :
OAIster
Journal :
Niemann , C U , Jurlander , J , Daugaard , G & Friis-Hansen , L 2009 , ' [Multi-facetted clinical presentation of thrombotic thrombocytopenic purpura] ' , Ugeskrift for læger , bind 171 , nr. 5 , s. 340-342 .
Notes :
Danish
Publication Type :
Electronic Resource
Accession number :
edsoai.on1322592241
Document Type :
Electronic Resource