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CDy14:A novel biofilm probe targeting exopolysaccharide Psl

Authors :
Kwon, Haw Young
Kim, Jun Young
Lee, Jung Yeol
Yam, Joey Kuok Hoong
Hultqvist, Louise Dahl
Xu, Wang
Rybtke, Morten
Tolker-Nielsen, Tim
Kim, Jong Jin
Kang, Nam Young
Yang, Liang
Park, Sung Jin
Givskov, Michael
Chang, Young Tae
Kwon, Haw Young
Kim, Jun Young
Lee, Jung Yeol
Yam, Joey Kuok Hoong
Hultqvist, Louise Dahl
Xu, Wang
Rybtke, Morten
Tolker-Nielsen, Tim
Kim, Jong Jin
Kang, Nam Young
Yang, Liang
Park, Sung Jin
Givskov, Michael
Chang, Young Tae
Source :
Kwon , H Y , Kim , J Y , Lee , J Y , Yam , J K H , Hultqvist , L D , Xu , W , Rybtke , M , Tolker-Nielsen , T , Kim , J J , Kang , N Y , Yang , L , Park , S J , Givskov , M & Chang , Y T 2018 , ' CDy14 : A novel biofilm probe targeting exopolysaccharide Psl ' , Chemical Communications , vol. 54 , no. 84 , pp. 11865-11868 .
Publication Year :
2018

Abstract

Detection of biofilm bacteria would be an ideal method for the physicians to diagnose chronic bacterial infections directly, but there are few imaging probes available so far. Here, we report the development of a novel biofilm detecting fluorescent probe, CDy14, through an unbiased screening of a fluorescence library and elucidated its binding partner Psl, an exopolysaccharide of the biofilm.

Details

Database :
OAIster
Journal :
Kwon , H Y , Kim , J Y , Lee , J Y , Yam , J K H , Hultqvist , L D , Xu , W , Rybtke , M , Tolker-Nielsen , T , Kim , J J , Kang , N Y , Yang , L , Park , S J , Givskov , M & Chang , Y T 2018 , ' CDy14 : A novel biofilm probe targeting exopolysaccharide Psl ' , Chemical Communications , vol. 54 , no. 84 , pp. 11865-11868 .
Notes :
English
Publication Type :
Electronic Resource
Accession number :
edsoai.on1322717286
Document Type :
Electronic Resource