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MYO-MRI diagnostic protocols in genetic myopathies
- Source :
- Chardon , J W , Díaz-Manera , J , Tasca , G , Bönnemann , C G , Gómez-Andrés , D , Heerschap , A , Mercuri , E , Muntoni , F , Pichiecchio , A , Ricci , E , Walter , M C , Hanna , M , Jungbluth , H , Morrow , J M , Torrón , R F , Udd , B , Vissing , J , Yousry , T , Quijano-Roy , S , Straub , V , Carlier , R Y & MYO-MRI Working Group 2019 , ' MYO-MRI diagnostic protocols in genetic myopathies ' , Neuromuscular Disorders , vol. 29 , no. 11 , pp. 827-841 .
- Publication Year :
- 2019
-
Abstract
- Whole-body magnetic resonance imaging has emerged as a useful imaging tool in diagnosing and characterizing the progression of myopathies and muscular dystrophies. Whole-body MRI indications and diagnostic efficacy are becoming better defined with the increasing number of cases, publications and discussions within multidisciplinary working groups. Advanced Whole-body MRI protocols are rapid, lower cost, and well-tolerated by patients. Accurate interpretation of muscle Whole-body MRI requires a detailed knowledge of muscle anatomy and differential pattern of involvement in muscle diseases. With the surge in recently identified novel genetic myopathies, Whole-body MRI will become increasingly useful for phenotypic validation of genetic variants of unknown significance. In addition, Whole-body MRI will be progressively used as a biomarker for disease progression and quantify response to therapy with the emergence of novel disease modifying treatments. This review outlines Whole-body MRI indications and updates refined protocols and provides a comprehensive overview of the diagnostic utility and suggested methodology of Whole-body MRI for pediatric and adult patients with muscle diseases.
Details
- Database :
- OAIster
- Journal :
- Chardon , J W , Díaz-Manera , J , Tasca , G , Bönnemann , C G , Gómez-Andrés , D , Heerschap , A , Mercuri , E , Muntoni , F , Pichiecchio , A , Ricci , E , Walter , M C , Hanna , M , Jungbluth , H , Morrow , J M , Torrón , R F , Udd , B , Vissing , J , Yousry , T , Quijano-Roy , S , Straub , V , Carlier , R Y & MYO-MRI Working Group 2019 , ' MYO-MRI diagnostic protocols in genetic myopathies ' , Neuromuscular Disorders , vol. 29 , no. 11 , pp. 827-841 .
- Notes :
- English
- Publication Type :
- Electronic Resource
- Accession number :
- edsoai.on1322742196
- Document Type :
- Electronic Resource