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Metabolome-proteome differentiation coupled to microbial divergence.

Authors :
Handelsman, J
Wilmes, P
Bowen, BP
Thomas, BC
Mueller, RS
Denef, VJ
VerBerkmoes, NC
Hettich, RL
Northen, TR
Banfield, JF
Handelsman, J
Wilmes, P
Bowen, BP
Thomas, BC
Mueller, RS
Denef, VJ
VerBerkmoes, NC
Hettich, RL
Northen, TR
Banfield, JF
Publication Year :
2010

Abstract

Tandem high-throughput proteomics and metabolomics were employed to functionally characterize natural microbial biofilm communities. Distinct molecular signatures exist for each analyzed sample. Deconvolution of the high-resolution molecular data demonstrates that identified proteins and detected metabolites exhibit organism-specific correlation patterns. These patterns are reflective of the functional differentiation of two bacterial species that share the same genus and that co-occur in the sampled microbial communities. Our analyses indicate that the two species have similar niche breadths and are not in strong competition with one another.

Details

Database :
OAIster
Publication Type :
Electronic Resource
Accession number :
edsoai.on1340013128
Document Type :
Electronic Resource