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Defining oligometastatic non-small cell lung cancer: A simulated multidisciplinary expert opinion

Authors :
Hendriks, Lizza E. L.
Dooms, Christophe
Berghmans, Thierry
Novello, Silvia
Levy, Antonin
De Ruysscher, Dirk
Hasan, Baktiar
Levra, Matteo Giaj
Levra, Niccolo Giaj
Besse, Benjamin
Vansteenkiste, Johan
Dingemans, Anne-Marie C.
European Organisation for Research and Treatment of Cancer (EORTC) Lung Cancer Group
Hendriks, Lizza E. L.
Dooms, Christophe
Berghmans, Thierry
Novello, Silvia
Levy, Antonin
De Ruysscher, Dirk
Hasan, Baktiar
Levra, Matteo Giaj
Levra, Niccolo Giaj
Besse, Benjamin
Vansteenkiste, Johan
Dingemans, Anne-Marie C.
European Organisation for Research and Treatment of Cancer (EORTC) Lung Cancer Group
Source :
European Journal of Cancer vol.123 (2019) p.28-35 [ISSN 0959-8049]
Publication Year :
2019

Abstract

Introduction: Synchronous oligometastatic non-small cell lung cancer (NSCLC) definition varies from 1 metastasis in 1 organ (tumour-node-metastasis 8 [TNM8]), 1-3 metastases (European Society for Medical Oncology [ESMO]),Methods: In December 2017, 10 real-life multidisciplinary team (MDT) discussed patients (good condition, no significant comorbidities, F-18-fluorodeoxyglucose positron emission tomography/brain magnetic resonance imaging staged, all <5 metastases, 9/10Results: Twenty-six of 33 experts (24 centres) replied: 8 medical oncologists, 7 pulmonologists, 7 radiation oncologists, 4 thoracic surgeons. Sixty-two percent of respondents discussed the cases with their MDT. One case had 100% oligometastatic consensus, and 3 cases had >90% consensus; the number of treatment proposals varied between 3 and 8. Radical treatment was more often offered in case of single metastasis or N0. Compared with 2012, there was a trend towards a more conservative oligometastatic definition and chemotherapy was more frequently included in the treatment proposal.Conclusions: Oligometastatic NSCLC definition was conservative. The number of organs, MLN status and radical treatment possibility seem to be components of daily practice oligometastatic definition. (C) 2019 Elsevier Ltd. All rights reserved.

Details

Database :
OAIster
Journal :
European Journal of Cancer vol.123 (2019) p.28-35 [ISSN 0959-8049]
Notes :
DOI: 10.1016/j.ejca.2019.09.013, English
Publication Type :
Electronic Resource
Accession number :
edsoai.on1363319744
Document Type :
Electronic Resource