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Estrogen receptor antagonists are anti-cryptococcal agents that directly bind EF hand proteins and synergize with fluconazole in vivo

Authors :
Madhani, Hiten
Madhani, Hiten
Butts, A
Koselny, K
Chabrier-Roselló, Y
Semighini, CP
Brown, JCS
Wang, X
Annadurai, S
DiDone, L
Tabroff, J
Childers, WE
Madhani, Hiten
Madhani, Hiten
Butts, A
Koselny, K
Chabrier-Roselló, Y
Semighini, CP
Brown, JCS
Wang, X
Annadurai, S
DiDone, L
Tabroff, J
Childers, WE
Publication Year :
2014

Abstract

Cryptococcosis is an infectious disease of global significance for which new therapies are needed. Repurposing previously developed drugs for new indications can expedite the translation of new therapies from bench to beside. Here, we characterized the ant

Details

Database :
OAIster
Publication Type :
Electronic Resource
Accession number :
edsoai.on1367641130
Document Type :
Electronic Resource