Palladium nanodendrites uniformly deposited on the surface of polymers as an efficient and recyclable catalyst for direct drug modification via Z-selective semihydrogenation of alkynes

The preparation of new monodisperse polycrystalline palladium nanoparticles uniformly distributed on the surface of polymers, by simply adding a palladium(II) solution in water to the polymers, is described. The polymer supported palladium nanoparticles material was used as an efficient portable and reusable catalyst for the stereoselective semihydrogenation reaction of internal alkynes to (Z)-alkenes in green solvents.
We gratefully acknowledge financial support from the Ministerio de Economía y Competitividad, Spain, and Fondo Europeo de Desarrollo Regional (FEDER) (Projects CTQ2015-71353-R and MAT2017-84501-R) and Junta de Castilla y León, Consejería de Educación y Cultura y Fondo Social Europeo (Projects BU051U16 and BU061U16). This research has made use of the high performance computing resources of the Castilla y León Supercomputing Center (SCAYLE, https://www.scayle.es), financed by the European Regional Development Fund (ERDF). J. G.-C. thanks Ministerio de Economía y Competitividad for his predoctoral FPU fellowship. This paper is dedicated to the memory of the late Dr Stefano Marcaccini.