Back to Search
Start Over
Determinants and reference values for blood volume and total hemoglobin mass in women and men
- Source :
- Oberholzer , L , Montero , D , Robach , P , Siebenmann , C , Ryrsøe , C K , Bonne , T C , Breenfeldt Andersen , A , Bejder , J , Karlsen , T , Edvardsen , E , Rønnestad , B R , Hamarsland , H , Cepeda-Lopez , A C , Rittweger , J , Treff , G , Ahlgrim , C , Almquist , N W , Hallén , J & Lundby , C 2024 , ' Determinants and reference values for blood volume and total hemoglobin mass in women and men ' , American Journal of Hematology , vol. 99 , no. 1 , pp. 88-98 .
- Publication Year :
- 2024
-
Abstract
- Blood volume (BV) is an important clinical parameter and is usually reported per kg of body mass (BM). When fat mass is elevated, this underestimates BV/BM. One aim was to study if differences in BV/BM related to sex, age, and fitness would decrease if normalized to lean body mass (LBM). The analysis included 263 women and 319 men (age: 10–93 years, body mass index: 14–41 kg/m2) and 107 athletes who underwent assessment of BV and hemoglobin mass (Hbmass), body composition, and cardiorespiratory fitness. BV/BM was 25% lower (70.3 ± 11.3 and 80.3 ± 10.8 mL/kgBM) in women than men, respectively, whereas BV/LBM was 6% higher in women (110.9 ± 12.5 and 105.3 ± 11.2 mL/kgLBM). Hbmass/BM was 34% lower (8.9 ± 1.4 and 11.5 ± 11.2 g/kgBM) in women than in men, respectively, but only 6% lower (14.0 ± 1.5 and 14.9 ± 1.5 g/kgLBM)/LBM. Age did not affect BV. Athlete's BV/BM was 17.2% higher than non-athletes, but decreased to only 2.5% when normalized to LBM. Of the variables analyzed, LBM was the strongest predictor for BV (R2 =.72, p <.001) and Hbmass (R2 =.81, p <.001). These data may only be valid for BV/Hbmass when assessed by CO re-breathing. Hbmass/LBM could be considered a valuable clinical matrix in medical care aiming to normalize blood homeostasis.
Details
- Database :
- OAIster
- Journal :
- Oberholzer , L , Montero , D , Robach , P , Siebenmann , C , Ryrsøe , C K , Bonne , T C , Breenfeldt Andersen , A , Bejder , J , Karlsen , T , Edvardsen , E , Rønnestad , B R , Hamarsland , H , Cepeda-Lopez , A C , Rittweger , J , Treff , G , Ahlgrim , C , Almquist , N W , Hallén , J & Lundby , C 2024 , ' Determinants and reference values for blood volume and total hemoglobin mass in women and men ' , American Journal of Hematology , vol. 99 , no. 1 , pp. 88-98 .
- Notes :
- application/pdf, English
- Publication Type :
- Electronic Resource
- Accession number :
- edsoai.on1439553024
- Document Type :
- Electronic Resource