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Population genomics of post-glacial western Eurasia

Authors :
Lundbeck Foundation
Novo Nordisk Foundation
Wellcome Trust
Carlsberg Foundation
Danish National Research Foundation
University of Copenhagen
Ferring Pharmaceuticals
Swedish Foundation for Humanities and Social Sciences
Villum Fonden
Independent Research Fund Denmark
Hanne and Torkel Weis-Fogh Fund
Wellcome
Swiss National Science Foundation
European Research Council
Aarhus University Research Foundation
Ministry of Education and Science (Kazakhstan)
Ministerio de Economía y Competitividad (España)
Ministero dell'Istruzione, dell'Università e della Ricerca
Ministerio de Ciencia, Innovación y Universidades (España)
Agencia Estatal de Investigación (España)
Generalitat Valenciana
Nomis Foundation
European Commission
Ministry of Science and Higher Education of the Russian Federation
Ministry of Education, Science, Culture and Sports of the Republic of Armenia
National Institute of General Medical Sciences (US)
Sikora, Martin [0000-0003-2818-8319]
Lalueza-Fox, Carles [0000-0002-1730-5914]
Allentoft, Morten
Sikora, Martin
Refoyo-Martínez, Alba
Irving-Pease, Evan K.
Fischer, Anders
Barrie, William
Ingason, Andrés
Stenderup, Jesper
Sjögren, Karl-Göran
Pearson, Alice
Mota, Bárbara Sousa da
Schulz Paulsson, Bettina
Halgren, Alma
Macleod, Ruairidh
Jørkov, Marie Louise S.
Demeter, Fabrice
Sørensen, Lasse
Nielsen, Poul Otto
Henriksen, Rasmus A.
Vimala, Tharsika
McColl, Hugh
Margaryan, Ashot
Ilardo, Melissa
Vaughn, Andrew
Fischer Mortensen, Morten
Nielsen, Anne Birgitte
Ulfeldt Hede, Mikkel
Johannsen, Niels Nørkjær
Rasmussen, Peter
Vinner, Lasse
Renaud, Gabriel
Stern, Aaron
Trolle Jensen, Theis Zetner
Scorrano, Gabriele
Schroeder, Hannes
Lysdahl, Per
Ramsøe, Abigail Daisy
Skorobogatov, Andrei
Schork, Andrew Joseph
Rosengren, Anders
Ruter, Anthony
Outram, Alan
Timoshenko, Aleksey A.
Buzhilova, Alexandra
Coppa, Alfredo
Zubova, Alisa
Silva, Ana María
Hansen, Anders J.
Gromov, Andrey
Logvin, Andrey
Gotfredsen, Anne Birgitte
Nielsen, Bjarne Henning
González-Rabanal, Borja
Lalueza-Fox, Carles
McKenzie, Catriona J.
Gaunitz, Charleen
Blasco, Concepción
Liesau, Corina
Martínez-Labarga, Cristina
Pozdnyakov, Dmitri V.
Cuenca-Solana, David
Lordkipanidze, David O.
En’shin, Dmitri
Salazar García, Domingo Carlos
Price, T. Douglas
Borić, Dušan
Kostyleva, Elena
Veselovskaya, Elizaveta V.
Usmanova, Emma R.
Cappellini, Enrico
Petersen, Erik Brinch
Kannegaard, Esben
Radina, Francesca
Yediay, Fulya Eylem
Duday, Henri
Gutiérrez-Zugasti, Igor
Merts, Ilya
Potekhina, Inna
Shevnina, Irina
Altinkaya, Isin
Guilaine, Jean
Hansen, Jesper
Aura Tortosa, Joan Emili
Zilhão, João
Vega, Jorge
Pedersen, Kristoffer Buck
Tunia, Krzysztof
Zhao, Lei
Mylnikova, Liudmila N.
Larsson, Lars
Metz, Laure
Yepiskoposyan, Levon
Pedersen, Lisbeth
Sarti, Lucia
Orlando, Ludovic
Slimak, Ludovic
Klassen, Lutz
Blank, Malou
González-Morales, Manuel
Silvestrini, Mara
Vretemark, Maria
Nesterova, Marina S.
Rykun, Marina
Rolfo, Mario Federico
Szmyt, Marzena
Przybyła, Marcin
Calattini, Mauro
Sablin, Mikhail
Dobisíková, Miluše
Meldgaard, Morten
Johansen, Morten
Berezina, Natalia
Card, Nick
Saveliev, Nikolai A.
Poshekhonova, Olga
Rickards, Olga
Lozovskaya, Olga V.
Gábor, Olivér
Uldum, Otto Christian
Aurino, Paola
Kosintsev, Pavel
Courtaud, Patrice
Ríos, Patricia
Mortensen, Peder
Lotz, Per
Persson, Per
Bangsgaard, Pernille
Barros Damgaard, Peter de
Petersen, Peter Vang
Prieto Martínez, Pilar
Włodarczak, Piotr
Smolyaninov, Roman V.
Maring, Rikke
Menduiña, Roberto
Badalyan, Ruben
Iversen, Rune
Turin, Ruslan
Vasilyev, Sergey
Wåhlin, Sidsel
Borutskaya, Svetlana
Skochina, Svetlana
Sørensen, Søren Anker
Andersen, Søren H.
Jørgensen, Thomas
Serikov, Yuri B.
Molodin, Vyacheslav I.
Smrcka, Vaclav
Merts, Victor
Appadurai, Vivek
Moiseyev, Vyacheslav
Magnusson, Yvonne
Kjær, Kurt H.
Lynnerup, Niels
Lawson, Daniel J.
Sudmant, Peter H.
Rasmussen, Simon
Korneliussen, Thorfinn Sand
Durbin, Richard
Nielsen, Rasmus
Delaneau, Olivier
Werge, Thomas
Racimo, Fernando
Kristiansen, Kristian
Willerslev, Eske
Lundbeck Foundation
Novo Nordisk Foundation
Wellcome Trust
Carlsberg Foundation
Danish National Research Foundation
University of Copenhagen
Ferring Pharmaceuticals
Swedish Foundation for Humanities and Social Sciences
Villum Fonden
Independent Research Fund Denmark
Hanne and Torkel Weis-Fogh Fund
Wellcome
Swiss National Science Foundation
European Research Council
Aarhus University Research Foundation
Ministry of Education and Science (Kazakhstan)
Ministerio de Economía y Competitividad (España)
Ministero dell'Istruzione, dell'Università e della Ricerca
Ministerio de Ciencia, Innovación y Universidades (España)
Agencia Estatal de Investigación (España)
Generalitat Valenciana
Nomis Foundation
European Commission
Ministry of Science and Higher Education of the Russian Federation
Ministry of Education, Science, Culture and Sports of the Republic of Armenia
National Institute of General Medical Sciences (US)
Sikora, Martin [0000-0003-2818-8319]
Lalueza-Fox, Carles [0000-0002-1730-5914]
Allentoft, Morten
Sikora, Martin
Refoyo-Martínez, Alba
Irving-Pease, Evan K.
Fischer, Anders
Barrie, William
Ingason, Andrés
Stenderup, Jesper
Sjögren, Karl-Göran
Pearson, Alice
Mota, Bárbara Sousa da
Schulz Paulsson, Bettina
Halgren, Alma
Macleod, Ruairidh
Jørkov, Marie Louise S.
Demeter, Fabrice
Sørensen, Lasse
Nielsen, Poul Otto
Henriksen, Rasmus A.
Vimala, Tharsika
McColl, Hugh
Margaryan, Ashot
Ilardo, Melissa
Vaughn, Andrew
Fischer Mortensen, Morten
Nielsen, Anne Birgitte
Ulfeldt Hede, Mikkel
Johannsen, Niels Nørkjær
Rasmussen, Peter
Vinner, Lasse
Renaud, Gabriel
Stern, Aaron
Trolle Jensen, Theis Zetner
Scorrano, Gabriele
Schroeder, Hannes
Lysdahl, Per
Ramsøe, Abigail Daisy
Skorobogatov, Andrei
Schork, Andrew Joseph
Rosengren, Anders
Ruter, Anthony
Outram, Alan
Timoshenko, Aleksey A.
Buzhilova, Alexandra
Coppa, Alfredo
Zubova, Alisa
Silva, Ana María
Hansen, Anders J.
Gromov, Andrey
Logvin, Andrey
Gotfredsen, Anne Birgitte
Nielsen, Bjarne Henning
González-Rabanal, Borja
Lalueza-Fox, Carles
McKenzie, Catriona J.
Gaunitz, Charleen
Blasco, Concepción
Liesau, Corina
Martínez-Labarga, Cristina
Pozdnyakov, Dmitri V.
Cuenca-Solana, David
Lordkipanidze, David O.
En’shin, Dmitri
Salazar García, Domingo Carlos
Price, T. Douglas
Borić, Dušan
Kostyleva, Elena
Veselovskaya, Elizaveta V.
Usmanova, Emma R.
Cappellini, Enrico
Petersen, Erik Brinch
Kannegaard, Esben
Radina, Francesca
Yediay, Fulya Eylem
Duday, Henri
Gutiérrez-Zugasti, Igor
Merts, Ilya
Potekhina, Inna
Shevnina, Irina
Altinkaya, Isin
Guilaine, Jean
Hansen, Jesper
Aura Tortosa, Joan Emili
Zilhão, João
Vega, Jorge
Pedersen, Kristoffer Buck
Tunia, Krzysztof
Zhao, Lei
Mylnikova, Liudmila N.
Larsson, Lars
Metz, Laure
Yepiskoposyan, Levon
Pedersen, Lisbeth
Sarti, Lucia
Orlando, Ludovic
Slimak, Ludovic
Klassen, Lutz
Blank, Malou
González-Morales, Manuel
Silvestrini, Mara
Vretemark, Maria
Nesterova, Marina S.
Rykun, Marina
Rolfo, Mario Federico
Szmyt, Marzena
Przybyła, Marcin
Calattini, Mauro
Sablin, Mikhail
Dobisíková, Miluše
Meldgaard, Morten
Johansen, Morten
Berezina, Natalia
Card, Nick
Saveliev, Nikolai A.
Poshekhonova, Olga
Rickards, Olga
Lozovskaya, Olga V.
Gábor, Olivér
Uldum, Otto Christian
Aurino, Paola
Kosintsev, Pavel
Courtaud, Patrice
Ríos, Patricia
Mortensen, Peder
Lotz, Per
Persson, Per
Bangsgaard, Pernille
Barros Damgaard, Peter de
Petersen, Peter Vang
Prieto Martínez, Pilar
Włodarczak, Piotr
Smolyaninov, Roman V.
Maring, Rikke
Menduiña, Roberto
Badalyan, Ruben
Iversen, Rune
Turin, Ruslan
Vasilyev, Sergey
Wåhlin, Sidsel
Borutskaya, Svetlana
Skochina, Svetlana
Sørensen, Søren Anker
Andersen, Søren H.
Jørgensen, Thomas
Serikov, Yuri B.
Molodin, Vyacheslav I.
Smrcka, Vaclav
Merts, Victor
Appadurai, Vivek
Moiseyev, Vyacheslav
Magnusson, Yvonne
Kjær, Kurt H.
Lynnerup, Niels
Lawson, Daniel J.
Sudmant, Peter H.
Rasmussen, Simon
Korneliussen, Thorfinn Sand
Durbin, Richard
Nielsen, Rasmus
Delaneau, Olivier
Werge, Thomas
Racimo, Fernando
Kristiansen, Kristian
Willerslev, Eske
Publication Year :
2024

Abstract

Western Eurasia witnessed several large-scale human migrations during the Holocene1,2,3,4,5. Here, to investigate the cross-continental effects of these migrations, we shotgun-sequenced 317 genomes—mainly from the Mesolithic and Neolithic periods—from across northern and western Eurasia. These were imputed alongside published data to obtain diploid genotypes from more than 1,600 ancient humans. Our analyses revealed a ‘great divide’ genomic boundary extending from the Black Sea to the Baltic. Mesolithic hunter-gatherers were highly genetically differentiated east and west of this zone, and the effect of the neolithization was equally disparate. Large-scale ancestry shifts occurred in the west as farming was introduced, including near-total replacement of hunter-gatherers in many areas, whereas no substantial ancestry shifts happened east of the zone during the same period. Similarly, relatedness decreased in the west from the Neolithic transition onwards, whereas, east of the Urals, relatedness remained high until around 4,000 BP, consistent with the persistence of localized groups of hunter-gatherers. The boundary dissolved when Yamnaya-related ancestry spread across western Eurasia around 5,000 BP, resulting in a second major turnover that reached most parts of Europe within a 1,000-year span. The genetic origin and fate of the Yamnaya have remained elusive, but we show that hunter-gatherers from the Middle Don region contributed ancestry to them. Yamnaya groups later admixed with individuals associated with the Globular Amphora culture before expanding into Europe. Similar turnovers occurred in western Siberia, where we report new genomic data from a ‘Neolithic steppe’ cline spanning the Siberian forest steppe to Lake Baikal. These prehistoric migrations had profound and lasting effects on the genetic diversity of Eurasian populations.

Details

Database :
OAIster
Notes :
English
Publication Type :
Electronic Resource
Accession number :
edsoai.on1442728781
Document Type :
Electronic Resource