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Gold(I)-Catalyzed 1,6-Enyne Single-Cleavage Rearrangements: The Complete Picture

Authors :
Universitat Rovira i Virgili
García-Padilla, E; Maseras, F; Echavarren, AM
Universitat Rovira i Virgili
García-Padilla, E; Maseras, F; Echavarren, AM
Source :
Acs Organic And Inorganic Au; 10.1021/acsorginorgau.3c00028; Acs Organic And Inorganic Au. 3 (5): 312-320
Publication Year :
2023

Abstract

We identify the factors that rule the selectivity insingle-cleavageskeletal rearrangements promoted by gold(I) catalysts. We find thatstereoconvergence is enabled by a rotational equilibrium when electron-richsubstituents are used. The anomalous Z-selectiveskeletal rearrangement is found to be due to electronic factors, whereas endo-selectivity depends on both steric and electronic factors.

Details

Database :
OAIster
Journal :
Acs Organic And Inorganic Au; 10.1021/acsorginorgau.3c00028; Acs Organic And Inorganic Au. 3 (5): 312-320
Publication Type :
Electronic Resource
Accession number :
edsoai.on1443596588
Document Type :
Electronic Resource