Comparability of Postural and Physical Activity Metrics from Different Accelerometer Brands Worn on the Thigh: Data Harmonization Possibilities

The aim was to establish which postural and physical activity outcomes are comparable across different accelerometer brands worn on the thigh when processed using open-source methods. Twenty participants wore four accelerometers (Axivity, ActiGraph, activPAL, GENEActiv) for three free-living days. Postural and physical activity outputs (average acceleration, intensity gradient, intensity of the most active 30 min, 60 min, and 8 h) were generated. "Postural outputs": Mean absolute percent errors (MAPEs) were low, reliability excellent, and equivalency within the 5% zone across all monitor pairings for sitting/lying and upright times, but not specific lying postures. "Physical activity outputs": MAPEs were higher and reliability lower than for sitting/lying and upright time. However, the majority of the outcomes were within the 10% equivalency zone for Axivity/GENEActiv and Axivity/ActiGraph pairings. Total sitting/lying and upright times show strong potential for harmonization across studies utilizing different thigh-worn accelerometers. The majority of acceleration outcomes compare well for Axivity, GENEActiv, and ActiGraph.