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1. MyD88 and IL-1: Loosening Treg cells’ firm grip.

Author

Campbell, Daniel J.

Subjects
*T cells, *IMMUNOSUPPRESSION, *IMMUNE response, *PATHOGENIC microorganisms, *INTERLEUKIN-1, *IMMUNOLOGY
Abstract

Immune suppression by Treg cells must be overcome to mount robust and effective anti-pathogen immune responses. A new paper in Immunity from Medzhitov and colleagues shows that IL-1-dependent activation of MyD88 promotes the development of Th1 cells by rendering them impervious to Treg cell-mediated inhibition. [ABSTRACT FROM AUTHOR]

Published
2014
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