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A new species of pycnogonid collected from the shallow waters of the Güllük Gulf (Aegean Sea), Anoplodactylus gullukensis n. sp., is described and illustrated. Description of taxonomic characters of this species are given and differences from related species are indicated. An identification key for Anoplodactylus species known from Türkiye is provided. [ABSTRACT FROM AUTHOR]

Bottom trawl samplings in Finike Bay revealed the existence of a brachyuran crab species, Homola barbata (Fabricius, 1793). H. barbata has been recorded only fourth time in Turkish waters, up to now. The existence of this rare species is recorded herein for the first time from the Finike Bay. It is the westernmost record of H. barbata on the Mediterranean coast of Türkiye. A distribution map of H. barbata in the eastern Mediterranean Sea is also presented, together with photographs of it. [ABSTRACT FROM AUTHOR]

Objective: Despite the rapidly developing diagnosis and treatment strategies in recent years, breast cancer is the most common type of cancer in women and is the cause of cancer-related death. Embelin is a potent XIAP inhibitor and a compound with antiestrogenic effects. In our study, we aimed to investigate the antitumoral activities of Embelin, which shows its effects through different cellular pathways, in two different human breast cancer cell lines, hormone receptor negative (MDA-MB-231) and positive (MCF-7) and we compared the effects of Embelin with tamoxifen and docetaxel, which are currently widely used in the treatment of breast cancer. Methods: To demonstrate the effects of Embelin at the cellular level, cytotoxicity analyzes and IC50 calculations were performed with a real-time cell electronic detection system (xCELLigence). For all subsequent studies, cells were treated with the IC50 dose of Embelin which determined in cytotoxicity assays and histopathological and immunohistochemical (Ki-67, Bax, Bcl-2, Cyclin D1) analyzes were performed. it was observed that Embelin had an antiproliferative effect in both cancer cell types in a dose and time dependent manner. IC50 values were calculated as 63 µM for MCF-7 and 64 µM for MDA-MB-231 from the proliferation curve graphs of Embelin exposed cells. As a result of the examination of the preparations stained with Hematoksylin-Eosin (H&E) and Ki-67, it was found that the cell number and Ki-67 proliferation index decreased (p<0.05) in cancer cells treated with Embelin. In order to analyze the effects of Embelin on the cell cycle, when we examined the preparations stained with Cyclin D1, it was observed that embelin decreased the Cyclin D1 levels required for the S1 phase of the cell cycle (p<0.05). In order to see the effect of Embelin on apoptotic pathways, preparations stained with proapoptotic Bax and antiapoptotic Bcl-2 were examined. Accordingly, while Bax expression level increased (p<0.05), Bcl-2 expression level decreased (p<0.05). Conclusion: In general, Embelin inhibits cancer cell proliferation in both breast cancer cell types, depending on dose and time. We found that Embelin was statistically more effective at the molecular level when compared to both Tamoxifen and Docetaxel, especially in hormone receptor-negative MDA MB-231 cells. By concluding that it is more effective especially in hormone receptor-negative breast cancer, Embelin may be an alternative new antitumoral agent in the treatment of breast cancer in the future. The results of this study may guide for in vivo studies in future. [ABSTRACT FROM AUTHOR]

A male specimen of Achelia langi (Dohrn, 1881) was found in Antalya Bay (Turkish coast of the Mediterranean Sea) at 1.5 m depth in July 2019. A distribution map of the species in the Mediterranean Sea is provided, together with a photograph and line drawing of the species. A. langi is reported in this study for the first time from Antalya Bay and the Mediterranean coast of Türkiye and also the third time from the eastern Mediterranean Sea. The record further extends the known distribution of this species from the Aegean Sea to the Mediterranean coast of Türkiye in the eastern Mediterranean Sea. [ABSTRACT FROM AUTHOR]

Objectives: Synthetic triterpenoids derived from oleanolic acid are known to have strong antiproliferative and antitumorigenic activity. The aim of this study is to investigate the the cytotoxic effects of CDDO-Me, a triterpenoid, on human breast cancer cell lines by comparing it with Tamoxifen and Docetaxel, which are used in the routine treatment of breast cancer. Material- Method: MCF-7 and MDA MB-231 were preferred as breast cancer cells to study the cytotoxic impressions of CDDO-Me, Docetaxel and Tamoxife. By applying various doses of each drug to both cells, its cytotoxic effects were determined by xCELLigence. Cell blocks were equipped and scoring the expressions of Ki-67 and Cyclin-D1 (proliferation index), antiapoptotic Bcl-2, proapoptotic Bax by histological and immunohistochemical staining in the blocks. Results: CDDO-Me, Docetaxel and Tamoxifen inhibited the cell viability of both cells. When the effects of CDDO-Me with Tamoxifen and Docetaxel were compared at the molecular level, it was concluded that CDDO-Me was statistically more effective than Tamoxifen and Docetaxel in terms of apoptosis pathway in both cell lines (p<0.001). In terms of cell cycle, CDDO-Me showed statistically similar effects with Tamoxifen in MCF-7 cells and Docetaxel was statistically more effective in this cell line (p<0.001) and CDDO-Me showed statistically similar effects with Docetaxel in MDA MB-231 cells and Tamoxifen was statistically more effective in this cell line (p<0.001). Conclusion: Although the antiproliferative and apoptosis-inducing effects of CDDO-Me differ in both types of breast cancer according to the effects of Tamoxifen and Docetaxel used in routine breast cancer treatment, CDDO-Me may be an alternative chemotherapeutic agent in the treatment of breast cancer and results of this study may guide in vivo studies in future. [ABSTRACT FROM AUTHOR]

Sampling studies on the Turkish Mediterranean coast revealed the presence of a species of Pycnogonida belonging to the genus Ammothella. This species is identified as A. longioculata (Faraggiana, 1940). This is herein reported for the first time from the Fethiye Bay and Mediterranean coast of Turkey. Therefore, the record further extends the known distribution of A. longioculata from the Aegean Sea to the Mediterranean coast of Turkey. A distribution map of the species in the Mediterranean Sea is provided, together with photographs of the species. This study is the only scientific report to date of the pycnogonids of the Fethiye Bay in Turkey. [ABSTRACT FROM AUTHOR]

Background Acute renal failure is commonly seen in the perioperative period. Ischemia–reperfusion (IR) injury plays a major role in acute renal failure and delayed graft function. MicroRNAs (miRs), which are pivotal modulators of cell activities, offer a major opportunity for affective diagnosis and treatment strategies because they are tissue specific and in the center of gene expression modulation. The effect of bardoxolone methyl (BM) on miR-21, miR-223-5p, and miR-125b in renal IR injury was evaluated in this study. Methods Wistar-Albino rats (12-16 wk old, weighing 300-350 g) were used in the study. Rats ( n = 6) were randomized into three groups (control, IR, and BM + IR). Tissue levels of miRs were analyzed with reverse transcription polymerase chain reaction. Results Significant reduction of urea and total oxidant status, increase of total antioxidant status, and oxidative stress index were identified in the IR + BM group compared with the IR group. Significant increases of miR-21 (2842.82-fold) and miR-125b (536.8-fold) were identified in the IR group compared with the control group; however, miR-223-5p levels did not show any significant difference. Also, miR-21 and miR-125b were significantly reduced in the IR + BM group compared with the IR group. Reduced histopathologic changes were observed in the IR + BM group. A significant decrease in the number of tunel-positive cells was identified in the IR + BM group compared with the IR group. Conclusions miR-125b was significantly increased in IR injury; thus, miR-125b can be a potential novel marker that can be used in diagnosis and treatment of renal IR injury. BM reduces miR-21 and miR-125b in case of IR injury and makes functional and histopathologic repairs. [ABSTRACT FROM AUTHOR]

Aim:MicroRNAs (miR) are important diagnostic and treatment targets due to their different tissue expressions and their central position in the regulation of gene expressions. miR studies might pioneer emerging of new diagnostic tools and treatment goals in kidney diseases. Captopril (CAP) and telmisartan (TEL) were shown to be effective in ischemia reperfusion (IR) injury. There is not any study about the effect of TEL and CAP over miR-21-320-146a. Our aim was to study the effects of CAP and TEL over miR on renal IR model. Methods:We used 12–16 weeks-old Wistar-Albino rats that weigh 300–350 g. Rats (n, 6) were randomized into four groups (Control, IR, IR + CAP, IR + TEL). Urea, creatinine, total antioxidant status (TAS), total oxidant status (TOS), oxidative stress index (OSI), super oxide dismutase (SOD), and miRs were analyzed. Results:Urea, creatinine, TOS, OSI levels of IR + CAP, and IR + TEL groups were lower comparing to IR group. TAS and SOD levels were higher in IR group than IR + TEL group. miR-21-320-146a showed increase in renal IR injury. miR-320, 146a showed significant decrease in IR + CAP and IR + TEL groups comparing to IR group. We showed histopathological recovery and decreased apoptosis in IR + CAP and IR + T groups than IR group. Conclusion:We, for the first time in the literature, showed that miR-320 is increased in IR injury. miR-320 might be a novel diagnosis and treatment target in renal ischemic reperfusion injury. Also, for the first time, we showed that CAP and TEL cause functional and histopathological recovery and lower miR-146a and miR-320. [ABSTRACT FROM AUTHOR]

Myxoglobulosis is a specific type of mucocele consisting of mucoid material. It is characterized by opaque, transparent globules that resemble "fish eggs" or "frogspawns". It is generally diagnosed incidentally during an appendectomy or an autopsy. In this paper, we aim to present the case of a 58-year-old male patient who was referred to our hospital because of abdominal pain and loss of appetite. The patient underwent an appendectomy. Opaque intraluminal globules were found in the appendectomy material. The globules resembled pearls and they were 2-3 mm in diameter. After histopathological examinations, the patient was diagnosed with myxoglobulosis accompanied with acute appendicitis. According to our research, this is the first case of myxoglobulosis in our country. [ABSTRACT FROM AUTHOR]

Anoplodactylus digitatus (Böhm, 1879) from Turkish waters was recorded for the first time. Specimens were collected at 3 sampling stations along the Mediterranean coast of Turkey. Some morphological features of the species are illustrated and its distribution in the Mediterranean Sea is shown. [ABSTRACT FROM AUTHOR]

A study of the sea spiders found in Mersin Bay, on the Mediterranean coast of Turkey, revealed 5 species belonging to 2 families (Ammotheidae and Phoxichilidiidae), which are new records for the region: Ammothella longipes (Hodge, 1864), A. appendiculata (Dohrn, 1881), Tanystylum orbiculare Wilson, 1878, T. conirostre (Dohrn, 1881), and A. pygmaeus (Hodge, 1864). Of these, 4 species (A. longipes, A. appendiculata, T. conirostre, A. pygmaeus) are new records for the Mediterranean coast of Turkey. In addition, T. conirostre and A. appendiculata are recorded for the first time from the Levantine Sea. Distribution of the species in Turkish waters is provided, together with photographs and line drawings of the species. [ABSTRACT FROM AUTHOR]

The Mediterranean green crab Carcinus aestuarii Nardo, 1847 (Crustacea, Brachyura, Portunidae) is a common inhabitant of the shallow waters of Homa Lagoon in Izmir Bay, Turkey, in the eastern Mediterranean. Monthly samples were collected in Homa Lagoon from June 2006 to May 2007 using trammel nets, fyke nets, beach seines and fence traps. In total, 608 males and 559 females of C. aestuarii were collected. The highest sex ratio (81-86% females) was recorded between October and December, and in August (58% females). Ovigerous females were obtained only from November to February with the highest ratio of ovigerous females (55%) observed in January 2007. The maturation curve presenting the carapace width showed that 50% of female crabs with the carapace width of 26.84 ±1.58 mm (r= 0.72) were physiologically mature. Regression analyses indicated that the number of eggs was positively correlated with carapace width and wet weight (P < 0.05, in both cases). [ABSTRACT FROM AUTHOR]

Some aspects concerning the reproduction, growth, and population dynamics of Plesionika martia were studied. Individuals were collected monthly between May 2008 and April 2009 during surveys conducted using a commercial trawl vessel. Samples were collected from Sığacık Bay (Aegean Sea, eastern Mediterranean) at depths ranging from 494 to 550 m. A total of 2110 individuals (766 males and 1344 females) were caught during these monthly surveys. The carapace length (CL) of the males ranged from 12.4 to 22.1 mm, and in females the CL ranged between 11.5 and 24.9 mm. The values of both CL and weight in females consistently exceeded that of males throughout the year. Although ovigerous females were observed throughout the year, the main reproductive period is suggested to be from May to December. In all groups examined, the values of allometric coeffi cient b were less than 3. Estimates of the Von Bertalanffy growth parameters were L¥ = 26.25 mm and k = 0.38 year-1 in females, and L¥ = 23.63 mm and k = 0.49 year-1 in males. [ABSTRACT FROM AUTHOR]

Determining the length-length and length-weight relationships and having access to the formulas on the relationships would enable researchers to indirectly estimate the approximate sizes of the organisms when consumed as prey items by examining one of the appendages found in the gut contents. in order to determine some morphometric characters of the Mediterranean green crab (Carcinus aestuarii Nardo, 1847) inhabiting Homa Lagoon, İzmir Bay, Turkey, crab samples were collected using trammel nets, fyke nets, beach seines, and fence traps in monthly intervals between June 2006 and May 2007. A total of 608 male and 559 female specimens were collected during the sampling period. The largest (in terms of carapace length: CL) female and male were 39.59 mm and 51.63 mm, respectively Morphometric equations for the conversions of length and weight were constructed separately for males, females, and the combined sexes. The equations for carapace width (CW) and right chela width (RChW) for males were found to be RChW = 0.373997 x CW - 3.90059, r² = 0.85. The relationship between carapace width (CW) and wet weight (WW) was determined to be LnCW = 0.3377 LnW + 2.6942, r² = 0.98 for males, LnCW = 0.3424 LnW + 2.6929, r² = 0.99 for females, and LnCW = 0.3361 LnW + 2.7019, r² = 0.99 for both sexes combined. Males were generally bigger than females. The average values of the carapace width for males and females were 44.58 ± 7.34 mm and 29.10 ± 7.07 mm, respectively. The CW/CL ratio for both sexes combined ranged from 1.22 to 1.26. [ABSTRACT FROM AUTHOR]

A study of the anomuran crustaceans found in Fethiye Bay, on the Mediterranean coast of Turkey, revealed 22 species belonging to 4 families (Diogenidae, Paguridae, Galathaeidae, and Porcellanidae). Of these, 14 species (Pagurus prideaux Leach, 1815, P. forbesii Bell, 1845, P. cheuvreuxi (Bouvier, 1896), P. cuanensis Bell, 1845, P. excavatus (Herbst, 1791), Anapagurus petiti Dechance and Forest, 1962, A. chiroacathus (Lilljeborg, 1856), A. bicorniger A. Milne Edwards and Bouvier, 1892, Dardanus calidus (Risso, 1827), Paguristes syrtensis De Saint Laurent, 1971, Diogenes pugilator (Roux, 1829), Galathea dispersa Bate, 1859, G. bolivari Zariquiey Álvarez, 1950, and Pisidia longimana (Risso, 1816)) were new records for Fethiye Bay, and 5 species (A. chiroacanthus, A. petiti, A. bicorniger, P. cheuvreuxi, and P. prideaux) were new records for the Mediterranean coast of Turkey. In addition, A. chiroacanthus was recorded for the first time from the Levantine Sea. Distribution of the species in the Turkish waters is provided, together with photographs of some of the species. [ABSTRACT FROM AUTHOR]

Knowledge about leptostracans from the Mediterranean Sea is still scarce. Examination of samples collected from the Aegean Sea off Turkey and from Cyprus in the eastern Mediterranean Sea revealed new localities and range extensions for 2 species of leptostracans: Nebalia strausi Risso, 1826, and N. kocatasiMoreira, Koçak, and Katagan, 2007. The record of N. kocatasi is the first for Cyprus and for the Levantine Basin. Additional specimens (Nebalia sp. 1 and Nebalia sp. 2) might prove to belong to 2 new species but the lack of material prevents their formal description. [ABSTRACT FROM AUTHOR]

Knowledge about leptostracans from the Mediterranean Sea is still scarce. Examination of samples collected from the Aegean Sea off Turkey and from Cyprus in the eastern Mediterranean Sea revealed new localities and range extensions for 2 species of leptostracans: Nebalia strausi Risso, 1826, and N. kocatasiMoreira, Koçak, and Katagan, 2007. The record of N. kocatasi is the first for Cyprus and for the Levantine Basin. Additional specimens (Nebalia sp. 1 and Nebalia sp. 2) might prove to belong to 2 new species but the lack of material prevents their formal description. [ABSTRACT FROM AUTHOR]

A new record of the leptostracan, Nebalia straus Risso, 1827 (Phyllocarida, Leptostraca) is reported from specimens collected at two sampling stations in Izmir Bay, Aegean Sea coast of Turkey between 2001 and 2002. The species is characterized by having a long antennular flagellum that bears up to 11-12 articles (in mature females), a long antennular scale 2.5 times as long as wide, a second maxilla with an exopod slightly longer than the first article of the endopod, and a stout distal spine on the fourth article of the antennule (two in ovigerous females). N. straus is recorded here for the first time from the eastern Mediterranean. [ABSTRACT FROM AUTHOR]

This article presents a study that was conducted to investigate the Anomura of the coasts of Iskenderun Bay, Turkey. The study area is located in the northeast of the Levantine Basin, and is 65 km in length and 35 km in width, covering an area of approximately 2275 kms. The bay has an average depth of 70 m. There is a euphotic water column and the amount of nutritional substances is 2-4 times higher than in truly offshore areas nearby. There is neither thermal stratification nor significant eutrophication, because of the dynamic structure of the bay. Since it has a large area of contact with the open sea, it is not affected by either the wind or by deep currents.

Acute generalized exanthematous pustulosis (AGEP) is a rare inflammatory dermatosis characterized by multiple nonfollicular pustules that occur on erythematous skin. Despite its similarity to pustular psoriasis and association with fever and leukocytosis, AGEP typically heals quickly. Etiologically, drugs and viruses have been suspected in most cases. Here, we present a case of AGEP, in a woman, that developed 1 day after starting bupropion for smoking cessation, as a rare side effect of the treatment. [ABSTRACT FROM AUTHOR]

Cholecystectomy is a common surgical procedure for various indications. Preoperative imaging is the main stay in the management of the patients. Routine and/or selective histopathological examination of the cholecystectomy materials have been discussed previously. However, incidental findings may be only observed with routine histopathological examination. Here, we report an incidental gallbladder signet cell carcinoma in a 66 years old patient. This case underlines the importance of routine histopathological examination after cholecystectomy. [ABSTRACT FROM AUTHOR]

Abstract Background Acute kidney injury is the most serious complication of crush syndrome. Hydrogen sulfide (H 2 S) is an endogenously produced gaseous signaling molecule. It is involved in homeostatic functions, such as blood pressure control, apoptosis, oxidative stress, and inflammation. In this study, effects of H 2 S on kidney injury were investigated in a rat model of crush syndrome. Methods Rats were divided into six groups (n = 8): Sham (steril saline ip), crush (sterile saline ip), crush + NaHS (sodium hydrosulfide, an H 2 S donor) (100 μmol/kg ip). All these groups were also separated as 3 and 24 h after decompression. Crush injury was induced by 6 h of direct compression to both hindlimbs of anesthetized rats with blocks weighing 3.6 kg each sides, followed by 3 or 24 h of decompression. Kidney injury molecule-1, neutrophil gelatinase–associated lipocalin, tumor-necrotizing factor-α, transforming growth factor-β, tissue total oxidant status, and total antioxidant status levels were measured in kidney homogenates 3 and 24 h after decompression. Serum creatine kinase, blood urea nitrogen, and creatinine levels were also measured. Apoptosis was assessed by TUNEL method. Bcl-2 was assessed by immunohistochemistry. Glomerular and tubular structures were also examined histopathologically. Results NaHS reduced kidney injury molecule-1, neutrophil gelatinase–associated lipocalin, tumor-necrotizing factor-α, transforming growth factor-β, total oxidant status levels, and increased total antioxidant status levels in kidney 3 and 24 h after decompression. Serum urea, creatinine, and creatine kinase levels also reduced with NaHS. NaHS decreased renal damage and apoptosis in crush-related acute kidney injury. Conclusions These results suggest that H 2 S could reduce crush-related acute kidney injury via anti-inflammatory, antioxidant, and antiapoptotic effects. [ABSTRACT FROM AUTHOR]

Purpose/Aim: Oxidative stress plays an important role in the pathogenesis of acute pancreatitis (AP). We compared the therapeutic effects of Ukrain (NSC 631570) andN-acetylcysteine (NAC) in rats with AP.Materials and Methods: Forty male Sprague Dawley rats were divided into four groups: controls; AP; AP with NAC; and AP with Ukrain. AP was induced via the ligation of the bile–pancreatic duct; drugs were administered intraperitoneally (i.p.) 30 min and 12 h after AP induction. Twenty-four hours after AP induction, animals were sacrificed and the pancreas was excised. Levels of malondialdehyde (MDA) and nitric oxide (NO), and activity levels of tumor necrosis factor (TNF)-α, and myeloperoxidase (MPO) were measured in tissue samples. Total oxidant status (TOS), total antioxidant status (TAS), and total bilirubin, as well as activity levels of aspartate aminotransferase (AST), alanine aminotransferase (ALT), amylase and lipase were measured in serum samples. Pancreatic tissue histopathology was also evaluated.Results: Test drugs reduced levels of MDA, NO, TNF-α, total bilirubin, AST, ALT, TOS and MPO, amylase and lipase activities (P< 0.001), and increased TAS (P< 0.001). Rats treated with test drugs attenuated AP-induced morphologic changes and decreased pancreatic damage scores compared with the AP group (P< 0.05). Both test drugs attenuated pancreatic damage, but the therapeutic effect was more pronounced in rats that received Ukrain than in those receiving NAC.Conclusions: These results suggest that treatment with Ukrain or NAC can reduce pancreatic damage via anti-inflammatory and antioxidant effects. [ABSTRACT FROM AUTHOR]

Objective: The aim of this study was to report our approach and outcomes of patients applied to our breast disease policlinic with mastalgia. Methods: The records of 877 patients presented with mastalgia to breast disease policlinic between April 2014 and January 2016 were examined retrospectively. Age, sex, body mass index (BMI), mammography breast imaging- reporting and data system score (BIRADS), ultrasonography evaluation, biopsy status, pathology results and operation procedures were investigated. Correlation between BIRADS score, age and BMI were analyzed. Results: All of the patients were female and median age was 49,0 years. Ultrasound showed breast mass in 283 (32.3%) patients and 165 (18.8%) of these underwent fine needle aspiration or true cut biopsy. Only 14 (8.5%) patients were diagnosed as malignant. Eight of the malignant cases had breast conserving surgery. Ages of the patients showed significant positive correlation with BIRADS classification values of the patients (r = 0.069, p = 0.04). However, BMI values did not correlate with BIRADS classification values of the patients. Conclusion: Mastalgia is a common symptom in women. In high risk patients for breast carcinoma, it should be investigated seriously. Both mammography and ultrasonography can be used at the same time for diagnoses. Especially in patients having dense breasts including young's, mammography alone cannot be satisfying for the evaluation. [ABSTRACT FROM AUTHOR]

The neutrophil-lymphocyte ratio (NLR) is a good marker of malignant diseases. The aim of this study was to investigate NLR as a diagnostic marker of thyroid cancer in patients with malignant thyroid diseases compared to those with benign thyroid diseases. Two hundred and fifty three patients were divided into two groups: benign and malignant thyroid disease patients. Malignant thyroid disease group was not sub-grouped further into differentiated and undifferentiated. The preoperative complete blood count and biochemical parameters, including NLR, were evaluated. The mean neutrophil count was found to be significantly higher, whereas the mean lymphocyte count was found to be significantly lower in the malignant group which includes 40 of the patients. As a result, NLR was significantly higher in the malignant group than in the benign group (p<0.001). This is the first study to show the value of NLR as a marker for malignant thyroid diseases including all subtypes. [ABSTRACT FROM AUTHOR]

Objective: The aim of this study is to evaluate the relationship between higher body mass index (BMI) and harvested total or metastatic lymph node numbers in patients who underwent surgery for colorectal cancers. Methods: Between March 2014 and January 2016, totally 71 patients who underwent laparoscopic or conventional surgery for colorectal cancer were evaluated retrospectively. The data of age, gender, BMI, surgical procedure, tumor localization, postoperative mortality status, total number of harvested and metastatic lymph node were collected. The patients having 24.9 (kg/m²) or lower BMI values were classified as normal (Group 1) and patients having BMI values of 25 or over were overweight (Group 2). Afterwards, the parameters between groups and the effect of higher BMI were analyzed. Results: The mean age of the patients was 64.5 ± 14 years. The average BMI value in group 1 was 22.3 (kg/ m²) and 27.0 (kg/m²) in group 2. According to localisation of tumor, transverse colon was the rare region for both groups. The common regions for tumor localisation in group 1 were right colon, sigmoid colon and rectum. In group 2 the common localisation for tumors were rectum, right colon and sigmoid colon. There was no difference between groups about postoperative mortality rates (p > 0.05). The mean of the total number of harvested lymph nodes were 14 in group 1 and 12 in group 2. There were no relationship between BMI and tumor diameter, total or metastatic number of harvested lymph nodes. Conclusion: Higher BMI values does not effect the number of excised total or metastatic lymph nodes and tumor diameters. Therefore, the surgeons should not hesitate in overweight patients cancer surgery for dissecting adequate number of lymph nodes. [ABSTRACT FROM AUTHOR]

Background The purpose of this study is to investigate the potential protective effect of the ukrain on ischemia-reperfusion (IR) injury in rat intestine, which has not previously been studied. Methods Thirty-one male Sprague-Dawley rats were randomly assigned to four groups, each consisting of eight rats as follows: (1) a sham group (S) (laparotomy, but no IR injury); (2) ukrain group (U) (no IR, and ukrain was administered intraperitoneally 1 h before laparotomy); (3) intestinal ischemia-reperfusion (II/R) group (30-min occlusion of the superior mesenteric artery then 2-h reperfusion); and (4) ukrain + II/R group (U + II/R) (30-min occlusion of the superior mesenteric artery then 2-h reperfusion; ukrain was administered intraperitoneally 1 h before IR). Results Serum total oxidant status (TOS) and total antioxidant status (TAS) were measured using Erel method. Oxidative stress index was calculated using the TOS/TAS ratio. TAS levels increased and TOS serum levels were also significantly decreased in the ukrain + IR group compared with the IR group (P = 0.000 and P = 0.015). Conclusions In this study, we demonstrated for the first time in literature that ukrain helps to prevent intestinal tissue breakdown against II/R injury and that this effect can be achieved by antioxidant activities. [ABSTRACT FROM AUTHOR]

This recent checklist of marine arthropods found on the coasts of Turkey represents a total of 1531 species belonging to 7 classes: Malacostraca (766 species), Maxillopoda (437 species), Ostracoda (263 species), Pycnogonida (27 species), Arachnida (26 species), Branchiopoda (7 species), and Insecta (5 species). Seventy-five species were classified as alien species in the region. This paper also includes the first record of the amphipod Melita valesi from the Levantine coast of Turkey (Kaş, Gulf of Antalya). [ABSTRACT FROM AUTHOR]