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Your search keyword '"Yingchao Xue"' showing total 2 results
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2 results on '"Yingchao Xue"'

1. Mechanical tension mobilizes Lgr6+ epidermal stem cells to drive skin growth.

Author

Yingchao Xue, Chenyi Lyu, Taylor, Ainsley, Van Ee, Amy, Kiemen, Ashley, Young Geun Choi, Khavanian, Nima, Henn, Dominic, Chaewon Lee, Hwang, Lisa, Wier, Eric, Wang, Saifeng, Sam Lee, Ang Li, Kirby, Charles, Gaofeng Wang, Pei-Hsun Wu, Wirtz, Denis, Garza, Luis A., and Reddy, Sashank K.

Subjects
*STEM cells, *WOUND healing, *LUNGS, *HAIR follicles, *STEM cell niches, *HIPPO signaling pathway, *DEVELOPMENTAL biology, *GREEN fluorescent protein
Abstract

The article presents a study which explores the Mechanical tension mobilizes leucine-rich repeat-containing G-protein coupled receptor 6 (LGR6+) epithelial stem cells to drive skin growth. It mentions the use of a system of controlled tissue expansion in mice to uncover cellular and molecular determinants of skin growth.

Published
2022
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2. Commensal microbiome promotes hair follicle regeneration by inducing keratinocyte HIF-1a signaling and glutamine metabolism.

Author

Gaofeng Wang, Sweren, Evan, Andrews, William, Yue Li, Junjun Chen, Yingchao Xue, Wier, Eric, Alphonse, Martin P., Li Luo, Yong Miao, Chen, Ruosi, Dongqiang Zeng, Sam Lee, Ang Li, Dare, Erika, Dongwon Kim, Archer, Nathan K., Reddy, Sashank K., Resar, Linda, and Zhiqi Hu

Subjects
*HAIR follicles, *WOUND healing, *GLUTAMINE synthetase, *GLUTAMINE, *GUT microbiome, *REGENERATION (Biology), *MOLECULAR biology, *KERATINOCYTES
Abstract

The article presents a study which showed that bacterially induced hypoxia drives increased glutamine metabolism in keratinocytes with attendant enhancement of skin and hair follicle regeneration through comprehensive multiomic analysis and single-cell RNA sequencing in murine skin. Topics discussed include hypoxia and glutamine metabolism in keratinocytes during WIHN, human and mouse keratinocyte isolation, culture, and treatment, and microarray and biofinformatic analysis.

Published
2023
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