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2. INTERNALIZATION AND RECYCLING PATHWAY OF RAT SOMATOSTATIN RECEPTOR SUBTYPE 3.

Author

Kreuzer, O. J., Schäfer, J., Roosterman, D., Déry, O., Bunnett, N. W., and Meyerhof, W.

Subjects
HORMONE receptors, SOMATOSTATIN, LABORATORY rats, GLYCOPROTEINS, EPITOPES
Abstract

The article presents an abstract of the study "Internalization and Recycling Pathway of Rat Somatostatin Receptor Subtype 3." Researchers in the study elongated somatostatin receptor subtype 3 (sst3) at its C-terminus with HSV glycoprotein D or EGFP epitopes. Results of the study suggest that internalization of SST-14/sst3 complexes propagates through the clathrin pathway leading to degradation of somatostatin in acidic vesicles and recycling of sst3 to the plasma membrane.

Published
1999

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