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The present study aimed to evaluate the in vitro antibacterial and antioxidant activities and the in vivo wound healing performance of a polysaccharide isolated from Glycyrrhiza glabra named PSG. It was structurally characterized by Fourier transformed infrared (FT-IR) spectroscopy, which confirmed the presence of different polysaccharides functional bands. The antioxidant capacity of PSG was determined in vitro and evaluated in vivo through the examination of wound healing capacity. Thirty two rats were randomly divided into four groups: group I was treated with physiological serum (negative control); group II was treated with “CYTOL CENTELLA®”; group III was treated with glycerol and group IV was treated with polysaccharide. The response to treatments was assessed by macroscopic, histologic, and biochemical parameters. Data revealed that our sample exhibited potential antioxidant activities and accelerated significantly the wound healing process, after ten days of treatment, proved by the higher wound appearance scores and a higher content of collagen confirmed by histological examination, when compared with control and “CYTOL CENTELLA®”. Overall, these findings proved that this polysaccharide isolated from Glycyrrhiza glabra could be considered as a natural bioactive polymer for therapeutic process in wound healing applications. Resumo O presente estudo teve como objetivo avaliar as atividades antibacteriana e antioxidante in vitro e o desempenho cicatricial in vivo de um polissacarídeo isolado de Glycyrrhiza glabra denominado PSG. Foi caracterizado estruturalmente por espectroscopia no infravermelho com transformada de Fourier (FT-IR), que confirmou a presença de diferentes bandas funcionais de polissacarídeos. A capacidade antioxidante da PSG foi determinada in vitro e avaliada in vivo através do exame da capacidade de cicatrização de feridas. Trinta e dois ratos foram divididos aleatoriamente em quatro grupos: o grupo I foi tratado com soro fisiológico (controle negativo); o grupo II foi tratado com “CYTOL CENTELLA®”; o grupo III foi tratado com glicerol e o grupo IV foi tratado com polissacarídeo. A resposta aos tratamentos foi avaliada por parâmetros macroscópicos, histológicos e bioquímicos. Os dados revelaram que nossa amostra apresentou atividades antioxidantes potenciais e acelerou significativamente o processo de cicatrização da ferida, após dez dias de tratamento, comprovado pelos maiores escores de aparência da ferida e maior teor de colágeno confirmado pelo exame histológico, quando comparado ao controle e “CYTOL CENTELLA® ”. No geral, esses achados provaram que esse polissacarídeo isolado de Glycyrrhiza glabra pode ser considerado um polímero bioativo natural para processos terapêuticos em aplicações de cicatrização de feridas.

Teenagers are the top consumer group and a potential market for the online retail sector. Teenagers are the age group that adopts technology the fastest, so they stand to gain the most from the availability of online shopping sites. This study was created by adapting earlier research that was done on live shopping broadcasts or live video shopping by Ma, Andersson, and Pitz in 2021. Both studies attempt to explain why viewers are devoted to particular channels by putting forth three types of connected consumer gratification in live shopping broadcasts. Hedonic motivation, utilitarian motivation, and social motivation are three different types of gratification. The method used in this study is descriptive qualitative. Data collection techniques start from data collection, data reduction, data presentation, and conclusions. From seven informants of high school / K students in the city of Surabaya. The results show that in the utilitarian motivation of Surabaya adolescent consumers get information and product picture more clearly thanks to live shopping broadcasts. On hedonic motivation, sellers on the direct shopping channel became the main factor that led to entertainment satisfaction during watching the live shopping channel. While social motivation in Tiktok LVS has a small role for Surabaya teenagers in using Tiktok LVS. Social interaction between seller-buyer is not an important issue regarding the audience's motivation to engage in watching certain channels on Tiktok LVS. Keywords: Online shop, consumer satisfaction, Tiktok Live Video Shopping

Purpose: This article provides a systematic review and analysis of group and single-case studies addressing augmentative and alternative communication (AAC) intervention with school-aged persons having autism spectrum disorder (ASD) and/or intellectual/developmental disabilities resulting in complex communication needs (CCNs). Specifically, we examined participant characteristics in group-design studies reporting AAC intervention outcomes and how these compared to those reported in single-case experimental designs (SCEDs). In addition, we compared the status of intervention features reported in group and SCED studies with respect to instructional strategies utilized. Participants: Participants included school-aged individuals with CCNs who also experienced ASD or ASD with an intellectual delay who utilized aided or unaided AAC. Method: A systematic review using descriptive statistics and effect sizes was implemented. Results: Findings revealed that participant features such as race, ethnicity, and home language continue to be underreported in both SCED and group-design studies. Participants in SCED investigations more frequently used multiple communication modes when compared to participants in group studies. The status of pivotal skills such as imitation was sparsely reported in both types of studies. With respect to instructional features, group-design studies were more apt to utilize clinical rather than educational or home settings when compared with SCED studies. In addition, SCED studies were more apt to utilize instructional methods that closely adhered to instructional features more typically characterized as being associated with behavioral approaches. Conclusion: The authors discuss future research needs, practice implications, and a more detailed specification of treatment intensity parameters for future research.

The acute and sub-chronic toxicities of the leaf extract of Newbouldia laevis, an ethnomedicinal herb use in the management of diabetes mellitus was investigated. For the acute toxicity study, 10 – 5000 mg/kg of the extract were administered orally to mice and obvious signs of toxic symptoms and mortality monitored for 24 h post extract administration. In the sub-chronic study, 302 and 604 mg/kg of the extract were orally administered daily for 90 days. Body weight changes as well as haematological and biochemical parameters were determined periodically. Qualitative phytochemistry was also conducted. Presence of flavonoids, saponins, tannins, reducing sugar, steroids, terpenoids, alkaloids and glycosides phytocompounds in the extract were detected. The oral LD50 was estimated to be above 5,000 mg/kg in mice. Ninety days oral administration of ethanol extract of N. laevis produced a significant (P

Background: Sleep disorders are common in Parkinson’s disease (PD) and include alterations in sleep-related EEG oscillations. Objective: This case-control study tested the hypothesis that patients with PD would have a lower density of Scalp-Slow Wave (SW) oscillations and higher slow-to-fast frequencies ratio in rapid eye movement (REM) sleep than non-PD controls. Other sleep-related quantitative EEG (qEEG) features were also examined, including SW morphology, sleep spindles, and Scalp-SW spindle phase-amplitude coupling. Methods: Polysomnography (PSG)-derived sleep EEG was compared between PD participants (n = 56) and non-PD controls (n = 30). Following artifact rejection, sleep qEEG analysis was performed in frontal and central leads. Measures included SW density and morphological features of SW and sleep spindles, SW-spindle phase-amplitude coupling, and spectral power analysis in Non-REM (NREM) and REM. Differences in qEEG features between PD and non-PD controls were compared using two-tailed Welch’s t-tests, and correction for multiple comparisons was performed per the Benjamini-Hochberg method. Results: SW density was lower in PD than in non-PD controls (F = 13.5, p’ = 0.003). The PD group also exhibited higher ratio of slow REM EEG frequencies (F = 4.23, p’ = 0.013), higher slow spindle peak frequency (F = 24.7, p’

The purpose of this study was to determine the effects of a reduced rim diameter (diameter 0.30 m) upon the kinematics of basketball free-throws. Ten male basketball players (mean ± s; age 17.1 ± 0.4 years, height 1.85 ± 1.43 m, mass 79.0 ± 5.3 kg) performed 8 direct successful free throws; 4 when using a standard 0.45 m diameter rim, and 4 with an 0.3 m diameter rim. Ball release parameters and joint angles at ball release were determined for each participant. The smaller rim was associated with significant increases (p < 0.0001) in ball release angle, ball release velocity, ball release height and shoulder joint angle at release. The reduced diameter rim can be advocated as a tactic for developing a higher ball release angle when training the shooting technique of young basketball players; this is likely to maximize the probability of a successful free-throw when attempted into a standard rim.

Intending to provide efficient and compact wastewater remediation, the present work is exploiting and introducing a novel composite prepared from porous starch aerogel (PSA) and organically modified Ca-montmorillonite (OMMT) for the removal of dyes from aqueous samples. First, potato starch components were used as a hydrolysis precursor to obtain PSA. The organoclay samples were prepared by co-intercalation of octadecylamine (ODA) into Ca-MMT using a low-temperature melting procedure. Composites with different starch-to-organoclay ratios of 10:1, 1:1, and 1:10 were then prepared by a blending process in distilled water and used for methyl orange (MO) uptake. The removal of methyl orange dyes increased with the amount of organoclay in the PSA matrix. Characterization revealed that organoclay synergy improved the PSA surface chemistry, while an important improvement in textural properties and thermal stability was also observed. The composite’s efficiency was demonstrated by high removal capabilities towards MO in most experimental runs, with a maximum adsorption capacity beyond 344.7 mg/g. The fitting result showed that MO adsorption follows a monolayer adsorption model, and chemisorption was the rate-controlling step. Nonetheless, this study proved the great potential of PSA/OMMT in dyeing wastewater treatment. Furthermore, starch modification is proven as an effective approach to enhancing the performance of starch-derived adsorbents.

Conditions that are associated with the way a person or group of people live are known as life conditions. Healthcare assiduity collects enormous complaint- related data that's unfortunately not booby-trapped to discover retired information that could be used for effective decision timber. This study aims to understand support vector machine and use it to prognosticate life conditions that an individual might be susceptible to. also, we propose and pretend an profitable machine literacy model as an volition to deoxyribonucleic acid testing that analyzes an existent’s life to identify possible pitfalls that form the foundation of individual tests and complaint forestallment, which may arise due to unhealthy diets and inordinate energy input, physical dormancy, etc. The simulated model will prove to be an intelligent low- cost volition to descry possible inheritable diseases caused by unhealthy cultures.

Introduction: Percutaneous nephrolithotomy (PCNL) is the gold standard for treating large or complex renal stones. Renal drainage after the procedure is most commonly via nephrostomy tube or indwelling ureteral stent, but the optimal duration of ureteral stents after PCNL is currently unknown. This study describes the post-operative events occurring with early stent removal on post-operative day one (POD1) in patients undergoing uncomplicated PCNL. Methods: We identified 336 patients from a single institution that underwent PCNL between 1/1/2020 and 6/1/2021. Of these, 106 patients with uncomplicated procedures that met inclusion criteria for early stent removal on POD1 were included. Retrospective chart review was performed to collect demographic information, operative data, and to identify adverse outcomes including additional procedures, patient telephone calls for symptoms, complications and emergency department (ED) visits. Results: Mean (SD) patient age was 54 (15.1) years and 56% of patients were morbidly obese (Body Mass Index [BMI] >30). Overall post-operative complication rate was low (18.8%) and limited primarily to Clavien I/II complications with only two Clavien III (1.9%) complications. Telephone calls or electronic messages were received from 37.7% of patients, with 16% requiring a visit to the ED or clinic. The most common reason for an ED visit was flank pain (11.1%). Conclusions: Early stent removal on POD1 may lead to pain-related telephone calls but appears to be a generally safe and effective management option in carefully selected patients undergoing uncomplicated PCNL.

Our Study aims were to test the impact of swimming practice on the development of postural stability among Tunisian Athletes. The analyses deal with the impact of the practice of swimming on the postural balance. They clarify the various constraints that influence the control mechanisms involved in maintaining the balance in the resort standing. Our study addresses 20 same age category male subjects (senior) returned in: an experimental group (10 swimmers, belonging to the Tunisian national team) and a control (no sports group 10). For this study we used the Neurocom version 8.0.2 system: scale Master® consisting of a flat form of force connected to a string of data to measure the speed of oscillation of the center of pressure in strong support bipedal, eyes open on ground. The results obtained showed no direct effect of the swimming practice on postural stability of Tunisian athletes. In fact swimming poses the need to evolve in an environment different from that in which any subject has built his balance, his motor skills of every day, the latter two are insured through the muscles; so balance follows the permanent integration of information transmitted by three receiving systems: Visual, proprioceptive and vestibular.

Acute radiation pneumonitis is a rare cause of pneumonitis. The diagnosis is considered in the presence of respiratory symptoms that appear with recent thoracic exposure. We report the case of a 67-year-old patient followed for mediastinal lymphoma who presented an acute pneumonitis when she started her radiotherapy sessions. Two diagnostics were suspected: radiotherapy toxicity or metastatic origin. Acute post-radiation pneumonitis can be very serious if the diagnostic is delayed. The diagnosis of acute post-radiation pneumonitis constitutes a diagnosis of elimination of any pneumonitis with an unfavorable evolution under antibiotic therapy, in the context of semi-recent thoracic radiotherapy.

Acute post-transfusion pneumopathy or TRALI (acronym for ''transfusion-related acute lung injury''), is defined by an acute respiratory distress syndrome occurring within six hours of a transfusion. It is a classic complication of LBP (Labile Blood Products) transfusion. Recent data have contributed to a better understanding of its mechanisms, two of which are well defined: an immunological conflict on the one hand, and activation of neutrophils by lipid factors on the other. The treatment of TRALI is of lesional pulmonary edema: oxygen therapy and respiratory assistance. We report a case of acute post-transfusion pneumonia, which occurred in a 23-year-old young man following the transfusion of a platelet pellet.

Objective Hospital acquired infections (HAIs) are one of the top 10 leading causes of death within the United States. While current standard of HAI risk prediction utilizes only a narrow set of predefined clinical variables, we propose a graph convolutional neural network (GNN)-based model which incorporates a wide variety of clinical features. Materials and Methods Our GNN-based model defines patients’ similarity based on comprehensive clinical history and demographics and predicts all types of HAI rather than focusing on a single subtype. An HAI model was trained on 38 327 unique hospitalizations while a distinct model for surgical site infection (SSI) prediction was trained on 18 609 hospitalization. Both models were tested internally and externally on a geographically disparate site with varying infection rates. Results The proposed approach outperformed all baselines (single-modality models and length-of-stay [LoS]) with achieved area under the receiver operating characteristics of 0.86 [0.84–0.88] and 0.79 [0.75–0.83] (HAI), and 0.79 [0.75–0.83] and 0.76 [0.71–0.76] (SSI) for internal and external testing. Cost-effective analysis shows that the GNN modeling dominated the standard LoS model strategy on the basis of lower mean costs ($1651 vs $1915). Discussion The proposed HAI risk prediction model can estimate individualized risk of infection for patient by taking into account not only the patient’s clinical features, but also clinical features of similar patients as indicated by edges of the patients’ graph. Conclusions The proposed model could allow prevention or earlier detection of HAI, which in turn could decrease hospital LoS and associated mortality, and ultimately reduce the healthcare cost.

Objective: To explore how sources of familial encouragement are associated with breast-feeding initiation and duration among a national sample participating in the US Special Supplemental Nutrition Program for Women, Infants, and Children (WIC). Design: This study uses the 2013–2015 WIC Infant and Toddler Feeding Practices Study 2 (WIC ITFPS-2) data. Breast-feeding initiation was measured at the first month, while duration was derived from a composite of the first 13 months. The analysis used logistic and linear regression to explore the association between encouragement sources and breast-feeding outcomes. Setting: A nationally representative sample of WIC participants in the USA. Participants: WIC participants who completed the 13-month interview of the WIC ITFPS-2 (n 2807). Results: Encouragement was significantly associated with both initiation and duration. Each source of encouragement was associated with a 3·2 (95 % CI 2·8, 3·8) increase in odds of initiating breast-feeding in the unadjusted model and 3·0 (95 % CI 2·5, 3·6) increased odds, controlling for age, education, nativity, poverty status, race and ethnicity ( Conclusions: Women who receive encouragement appear to be more likely to breastfeed. Additional work is needed to explore sources of encouragement and how to include them in intervention work.

Lead halide perovskite nanocrystals are promising materials for classical and quantum light emission. To understand these outstanding properties, a thorough analysis of the band-edge exciton emission is needed which is not reachable in ensemble and room temperature studies because of broadening effects. Here, we report on a cryogenic-temperature study of the photoluminescence of single CsPbBr$_3$ NCs in the intermediate quantum confinement regime. We reveal the size-dependence of the spectral features observed: the bright-triplet exciton energy splittings, the trion and biexciton binding energies as well as the optical phonon replica spectrum. In addition, we show that bright triplet energy splittings are consistent with a pure exchange model and that the variety of polarisation properties and spectra recorded can be rationalised simply by considering the orientation of the emitting dipoles and the populations of the emitting states.

Objective: Scalable digital learning environments are essential to sustain surgical training programs worldwide. Detailed images of surgeries enriched with educational annotations are vital to train the eyes of the learners. Here, we report a low-cost method, deployed in a low-resource setting in West Africa, which may contribute to the growth of use in open-sourced digital surgical resources world-wide. Design: This paper is based on the authors participatory and observational experiences creating surgical video content by way of recording surgical procedures and reflecting on field notes and video content. All surgeries were recorded between January and December 2018. Setting: Masanga Hospital, a rural district hospital in Sierra Leone, West Africa. Participants: Thirty-five patients undergoing inguinal hernia repair, elective caesarian section, salpingectomy, bowel resection, hydrocele repair, or below-knee amputation consented for recording their surgical procedure and using the anonymized material for educational purposes. Results: This manual for non-professional cinematographers provides chronological steps for shooting a surgical procedure in a low-resource setting. Recording a surgical procedure to explain surgical techniques, and perform quality assessment through error analysis and coaching requires more than just point-and-shoot. While taking into account local customs and possibilities, practical tips were provided to prepare for the set-up, and recording of a surgical procedure in a low-resourced setting. Conclusion: Commercially available digital video technology allows for filming high-quality surgical procedures for educational purposes at rural district hospitals in a low-resource setting.

International audience; Objectives: To assess the contribution of whole-body magnetic resonance imaging (WBMRI) and bone scintigraphy (BS) in addition to skeletal survey (SS) in detecting traumatic bone lesions and soft-tissue injuries in suspected child abuse.Methods: In this prospective, multicentre, diagnostic accuracy study, children less than 3 years of age with suspected physical abuse were recruited. Each child underwent SS, BS and WBMRI. A blinded first review was performed in consensus by five paediatric radiologists and three nuclear medicine physicians. A second review investigated discrepancies reported between the modalities using a consensus result of all modalities as the reference standard. We calculated the sensitivity, specificity and corresponding 95% confidence interval for each imaging modality (SS, WBMRI and BS) and for the combinations [SS + WBMRI] and [SS + BS].Results: One hundred seventy children were included of which sixty-four had at least one lesion. In total, 146 lesions were included. The sensitivity and specificity of each examination were, respectively, as follows: 88.4% [95% CI, 82.0-93.1] and 99.7% [95% CI, 99.5-99.8] for the SS, 69.9% [95% CI, 61.7-77.2] and 99.5% [95% CI, 99.2-99.7] for WBMRI and 54.8% [95% CI, 46.4-63.0] and 99.7% [95% CI, 99.5-99.9] for BS. Sensitivity and specificity were, respectively, 95.9% [95% CI, 91.3-98.5] and 99.2% [95% CI, 98.9-99.4] for the combination SS + WBMRI and 95.2% [95% CI, 90.4-98.1] and 99.4% [95% CI, 99.2-99.6] for the combination SS + BS, with no statistically significant difference between them.Conclusion: SS was the most sensitive independent imaging modality; however, the additional combination of either WBMRI or BS examinations offered an increased accuracy.Key points: • SS in suspected infant abuse was the most sensitive independent imaging modality in this study, especially for detecting metaphyseal and rib lesions, and remains essential for evaluation. • The combination of either SS + BS or SS + WBMRI provides greater accuracy in diagnosing occult and equivocal bone injuries in the difficult setting of child abuse. • WBMRI is a free-radiation technique that allows additional diagnosis of soft-tissue and visceral injuries.

Cosmological constraints from key probes of the Euclid imaging survey rely critically on the accurate determination of the true redshift distributions, $n(z)$, of tomographic redshift bins. We determine whether the mean redshift, $$, of ten Euclid tomographic redshift bins can be calibrated to the Euclid target uncertainties of $\sigma()$ is measured in each tomographic redshift bin to an accuracy of order 0.01 or better. By measuring the clustering redshifts on subsets of the full Flagship area, we construct scaling relations that allow us to extrapolate the method performance to larger sky areas than are currently available in the mock. For the full expected Euclid, BOSS, and DESI overlap region of approximately 6000 deg$^{2}$, the uncertainties attainable by clustering redshifts exceeds the Euclid requirement by at least a factor of three for both $n(z)$ models considered, although systematic biases limit the accuracy. Clustering redshifts are an extremely effective method for redshift calibration for Euclid if the sources of systematic biases can be determined and removed, or calibrated-out with sufficiently realistic simulations. We outline possible future work, in particular an extension to higher redshifts with quasar reference samples., Comment: 14 pages, 8 figures, accepted for publication in A&A

The Euclid space telescope will survey a large dataset of cosmic voids traced by dense samples of galaxies. In this work we estimate its expected performance when exploiting angular photometric void clustering, galaxy weak lensing and their cross-correlation. To this aim, we implement a Fisher matrix approach tailored for voids from the Euclid photometric dataset and present the first forecasts on cosmological parameters that include the void-lensing correlation. We examine two different probe settings, pessimistic and optimistic, both for void clustering and galaxy lensing. We carry out forecast analyses in four model cosmologies, accounting for a varying total neutrino mass, $M_\nu$, and a dynamical dark energy (DE) equation of state, $w(z)$, described by the CPL parametrisation. We find that void clustering constraints on $h$ and $\Omega_b$ are competitive with galaxy lensing alone, while errors on $n_s$ decrease thanks to the orthogonality of the two probes in the 2D-projected parameter space. We also note that, as a whole, the inclusion of the void-lensing cross-correlation signal improves parameter constraints by $10-15\%$, and enhances the joint void clustering and galaxy lensing Figure of Merit (FoM) by $10\%$ and $25\%$, in the pessimistic and optimistic scenarios, respectively. Finally, when further combining with the spectroscopic galaxy clustering, assumed as an independent probe, we find that, in the most competitive case, the FoM increases by a factor of 4 with respect to the combination of weak lensing and spectroscopic galaxy clustering taken as independent probes. The forecasts presented in this work show that photometric void-clustering and its cross-correlation with galaxy lensing deserve to be exploited in the data analysis of the Euclid galaxy survey and promise to improve its constraining power, especially on $h$, $\Omega_b$, the neutrino mass, and the DE evolution., Comment: 22 pages, 9 figures - published in A&A

There is an increased need of identifying reduced tillage method that improves soil organic matter and soil fertility and at the same time best crop performance in organic farming. This study assessed the effects of organically managed reduced tillage and conventional tillage on dynamic soil properties and winter triticale performance. Organic farm that has been treated with three different tillage systems for six consecutive years was used in this study at Drovendaal organic facility of Wageningen University and Research. The tillage systems included two reduced tillage NIT at 10 cm and ECO up to 20 cm deep and CON at a depth of 30 cm. The parameters evaluated are soil physico-chemical properties, leaf area index (LAI), plant dry matter, ear number per area, plant height and chlorophyll content (SPAD) at ear formation stage . Use of NIT led to higher SOM and N-NO3 of 13.03 mg kg-1 at 0-10 cm soil depth. Also, shallow soil depths had lower bulk density and penetration resistance compared to deeper depths but NIT had higher penetration resistance in all soil depths compared to ECO and CON. Based on crop performance, ECO and CON revealed a better crop performance than NIT. Therefore, ECO having intermediate potentials in soil properties and crop performance could be the right tillage system for organic crop production compared to NIT and CON. Moreover, ECO will be a suitable tillage system that improves soil fertility, mitigates greenhouse gases and at the same time influence high crop performance.

Visible light photooxidation of naphthols to produce naphthoquinones, such as the natural product juglone, has been known for decades and has been widely utilized to benchmark the performances of a variety of photocatalytic systems. We discovered that these transformations can occur without the help of a photocatalyst and, even more intriguingly, that the photocatatyst-free process provides higher yields compared to control experiments utilizing state-of-the-art photocatalysts. In addition, we demonstrate that naphthoquinones and their corresponding naphthol precursors can act as alternatives to commonly used organic and organometallic photocatalysts with applications to challenging targets, such as the antimalarial drug artemisinin. This approach was finally transposed in continuous flow reactors where high photocatalyst stability and process efficiency are demonstrated with a 23× improvement in the space-time yield.

The field experiment was conducted during Zaid mid of March – April 2022 at Crop Research Farm, Department of Agronomy, Sam Higginbottom University of Agriculture, Technology and Sciences, Prayagraj (U.P). The treatments consisted of three Plant growth regulators (Mepiquat chloride 180ppm, Naphthalene acetic acid 30ppm, Putrescine 40ppm) and three levels of Zinc sulphate (10, 20, 30 kg/ha ZnSO4) respectively. The experiment was laid out in randomized block design with ten treatments and were replicated thrice. The soil of experimental plot was sandy loamy in texture, nearly neutral in soil reaction (pH 7.2), low in organic carbon (0.48%) available N (171.48 kg/ha), available P (13.6 kg/ha) and available K (215.4 kg/ha). Results defined that maximum plant height (181.62 cm), dry weight (92.31 g/plant), Green fodder yield (32.7 t/ha) were significantly influenced with treatment-6 Naphthalene acetic acid 180ppm along with Zinc sulphate 30 kg/ha and Maximum No. of cobs/plant (3 cobs/plant), length of cob/plant (21.8 cm), girth of cob (9.3 cm), cob weight with husk (49.84 g), cob weight without husk (12.11 g), Cob yield (11.03 t/ha) were significantly influenced with the treatment-3 Mepiquat chloride 30ppm along with Zinc sulphate 30 kg/ha. Minimum parameters were recorded in treatment-10 control plot which is application of recommended dose of fertilizers 100:60:40 kg/ha NPK.

The aim was to assess the satisfaction ofwomen giving birth with the reception, the quality of care and the attitude of maternal and neonatal care providers. Materials and methods: This was a prospective descriptive analytical cross-sectional study over a 6-month periodfrom February 1, 2019 to July 31, 2019 in Fana. Results: The average age of women was 27.5 years with extremes of 15 and 40 years. They were 98.2% married. And 90.1% of them took care of their household. They were educated in 27.1% with only 2.6% who had a higher level of education. Direct admissions were 80% and referrals/evacuations accounted for 20% of the workforce. Pregnant women performed between 1 and 4 antenatal care in 87.2% and 4.8% did not provide any care. The majority of them consulted in the 3rd trimester of pregnancy. Pregnant women gave birth vaginally in 76.6% compared to 23.4% of caesarean section. Instrumental extractions are performed in 1.3% with 6cases of forceps and 2cases of suction cup. Hemorrhage, eclampsia, uterine rupture and infection are the main maternal complications observed. 99.2% of the care provided by qualified personnel. Care for sick and premature infants was inadequate. 98.7% of women gave birth were satisfied with the care. Conclusion: The quality of obstetric and neonatal care was generally satisfactory.

Objectives: Pharmacists’ responsibilities have become more patient-oriented so exploring patients’ satisfaction would lead to identifying and improving the quality of pharmaceutical services. The aim of the present study was to assess patients’ satisfaction with pharmaceutical services in Jordan Methods: A cross-sectional study was conducted between December 2018 and April 2019. Patients’ satisfaction was assessed using three subscales; managing therapy, interpersonal relationship, and general satisfaction, in addition, to the socio-demographic questionnaire. Participants were asked about the degree of their satisfaction with the pharmaceutical services in all subscales’ questions using a 5-point Likert scale. Results: A total of 1,333 patients participated in the study. The mean patient age was 32.4 years (SD = 11.6)52.5% (n = 700) were female. Patients had a good satisfaction score for overall pharmaceutical services with a mean score of 51.4 ± 11.4 out of 70. Among the subscales, the interpersonal relationship subscale showed a satisfaction score of 75.7% while the other two subscales (general satisfaction and managing therapy) showed slightly lower scores with 75.0% and 69.6%, respectively. Having good health and governmental or military health insurance, visiting the pharmacy more frequently, and dispensing medications from governmental hospitals, primary healthcare centers, or military hospital pharmacies were important predictors of better patient satisfaction with pharmaceutical services (p < 0.05). Conclusions: This study presents some nationwide patient-reported outcomes about patient satisfaction in general pharmacy settings in Jordan. Focusing on patients’ satisfaction while providing pharmaceutical services is needed.

Atualmente é crescente a preocupação da sociedade com as questões ambientais e com a disponibilidade de recursos hídricos. Embora o Brasil seja considerado um país hidro logicamente rico, a escassez de água é comum em algumas regiões, como o interior do Nordeste, onde há períodos muito longos de estiagem. As razões para esta escassez são numerosas; má gestão com recursos públicos e atividades ambientais como esgoto doméstico em rios resultando em problemas de saúde pública. A consequência disso afeta as águas superficiais, pois são mais vulneráveis a impactos do que aquelas encontradas em profundidades maiores. Diante do exposto, este trabalho teve como objetivo mostrar a importância da manutenção e manejo adequado das nascentes para mitigar a crise hídrica na zona rural do município de Mata Grande-Alagoas. A metodologia foi direcionada à pesquisa bibliográfica, seguida de pesquisa documental por meio de levantamento das nascentes do município de Mata Grande realizado pelo “Projeto Renascer” em conjunto com a prefeitura municipal. Os levantamentos de campo foram realizados in loco aplicados com dez proprietários de terras, sendo cinco com nascentes e cinco onde não existem recursos hídricos. Na metodologia de coleta de dados para análise, foi aplicado um questionário com um formulário de perguntas referentes às nascentes na zona rural e seus benefícios. São muitos os discursos relatando dificuldades de falta de água em locais onde ela não existe. O resultado mostrou a necessidade da prefeitura municipal de Mata Grande elaborar um projeto para recuperar as nascentes abandonadas e buscar outras formas de abastecimento de água, através da implantação de poços artesianos que irão beneficiar a população que sofre com a crise hídrica.

Background: Fever is a very common adaptive immune response in acute respiratory tract disorders during infancy. Antipyretic / analgesic drugs such as paracetamol (acetaminophen) are widely used to improve the comfort of the child. Objective: To determine the efficacy of paracetamol in symptomatic relief of upper respiratory tract infections in children aged 2 to 5 years. Study Design: Descriptive case series Study Setting: Department of Pediatrics, Ayub Teaching Hospital, Abbottabad Duration of study: Six months from October 13, 2020, to April 13, 2021 Subjects and methods: All children aged 2 to 5 years of either gender having upper respiratory tract infections and duration of symptoms of >2 days were consecutively enrolled. Patients were prescribed Paracetamol in a dose of 10 mg/kg/dose 6 hourly for 3 days. Patients were followed up after 3 days to see the efficacy of Paracetamol in symptomatic relief of upper respiratory tract infections. Results: Of 284 children, the mean age of the children was 4.01 ±1.10 years. There were 135 (47.5%) males and 149 (52.5%) females. The mean weight of the children was 12.36 ±3.42 kg. The mean duration of symptoms was 5.11 ±0.95 days. The efficacy of paracetamol in symptomatic relief of upper respiratory tract infection was found to be 184 (64.8%). A non-significant difference of efficacy of paracetamol was observed with age (p-value 0.578), gender (p-value 0.908), weight (pvalue 0.586), and duration of symptoms (p-value 0.872). Practical Implication: This study was planned to determine the efficacy of paracetamol in symptomatic relief of upper respiratory tract infections. The results of this study could be used in owing to locally produced evidence. Conclusion: The efficacy of paracetamol was observed in 64.8% children aged 2 to 5 years with symptomatic relief of upper respiratory tract infections in children. Keywords: Efficacy, Paracetamol, Children, Upper Respiratory Tract Infections

Background: Copper is a metal that is widely used in many fields such as industry and construction, etc. These different industrial sectors use acid solutions such as nitric acid and hydrochloric acid, etc. The use of acid solutions in the industrial environment causes degradation of materials. In recent decades, the use of corrosion inhibitors has become very essential. Objective: The objective of our study is to test the performance of meloxicam as a copper corrosion inhibitor in a nitric acid medium. Methods: The studies were conducted using the gravimetric method and density functional theory (DFT) at B3LYP/6-311G (d, p) level of theory. The inhibitory efficiency of the molecule increases with increasing concentration of Meloxicam, but decreases with increasing temperature. The adsorption of the molecule on the copper surface follows the Villamil model. Results: The thermodynamic quantities of adsorption and activation were determined and discussed. Quantum chemical calculations have allowed determining the molecular descriptors. Conclusion: There is a good agreement between the experimental and theoretical results. Electrochemical studies are envisaged.

Tuberculosis diagnosis might be delayed or missed in children with severe pneumonia because this diagnosis is usually only considered in cases of prolonged symptoms or antibiotic failure. Systematic tuberculosis detection at hospital admission could increase case detection and reduce mortality.We did a stepped-wedge cluster-randomised trial in 16 hospitals from six countries (Cambodia, Cameroon, Côte d'Ivoire, Mozambique, Uganda, and Zambia) with high incidence of tuberculosis. Children younger than 5 years with WHO-defined severe pneumonia received either the standard of care (control group) or standard of care plus Xpert MTB/RIF Ultra (Xpert Ultra; Cepheid, Sunnyvale, CA, USA) on nasopharyngeal aspirate and stool samples (intervention group). Clusters (hospitals) were progressively switched from control to intervention at 5-week intervals, using a computer-generated random sequence, stratified on incidence rate of tuberculosis at country level, and masked to teams until 5 weeks before switch. We assessed the effect of the intervention on primary (12-week all-cause mortality) and secondary (including tuberculosis diagnosis) outcomes, using generalised linear mixed models. The primary analysis was by intention to treat. We described outcomes in children with severe acute malnutrition in a post hoc analysis. This study is registered with ClinicalTrials.gov (NCT03831906) and the Pan African Clinical Trial Registry (PACTR202101615120643).From March 21, 2019, to March 30, 2021, we enrolled 1401 children in the control group and 1169 children in the intervention group. In the intervention group, 1140 (97·5%) children had nasopharyngeal aspirates and 942 (80·6%) had their stool collected; 24 (2·1%) had positive Xpert Ultra. At 12 weeks, 110 (7·9%) children in the control group and 91 (7·8%) children in the intervention group had died (adjusted odds ratio [OR] 0·986, 95% CI 0·597-1·630, p=0·957), and 74 (5·3%) children in the control group and 88 (7·5%) children in the intervention group had tuberculosis diagnosed (adjusted OR 1·238, 95% CI 0·696-2·202, p=0·467). In children with severe acute malnutrition, 57 (23·8%) of 240 children in the control group and 53 (17·8%) of 297 children in the intervention group died, and 36 (15·0%) of 240 children in the control group and 56 (18·9%) of 297 children in the intervention group were diagnosed with tuberculosis. The main adverse events associated with nasopharyngeal aspirates were samples with blood in 312 (27·3%) of 1147 children with nasopharyngeal aspirates attempted, dyspnoea or SpOSystematic molecular tuberculosis detection at hospital admission did not reduce mortality in children with severe pneumonia. High treatment and microbiological confirmation rates support more systematic use of Xpert Ultra in this group, notably in children with severe acute malnutrition.Unitaid and L'Initiative.For the French translation of the abstract see Supplementary Materials section.

Tulisan ini bertujuan untuk mengkaji tentang keabsahan aset kripto sebagai jaminan dalam akta perjanjian pinjaman dana berdasarkan hukum jaminan yang berlaku di Indonesia. Pada penelitian ini digunakan pendekatan secara Undang-Undang. Metode pengumpulan menggunakan literatur data dari buku-buku, Undang-Undang dan regulasi yang berlaku. Sumber hukum yang digunakan adalah bahan hukum primer, sekunder dan tersier. Hasil penelitian dapat disimpulkan bahwa penggunaan aset kripto sebagai objek jaminan fidusia dalam perjanjian pinjaman dana berdasarkan hukum positif di Indonesia dapat dilakukan, hal tersebut dikarenakan aset kripto memenuhi unsur barang yang dapat dijadikan jaminan fidusia, yaitu suatu benda yang dapat bernilai dan memiliki karakteristik sebagai benda bergerak tidak berwujud. Akta perjanjian pinjaman dana yang telah dibuat secara otentik oleh notaris dapat terdegradasi apabila unsur materil dan formilnya bertentangan terhadap peraturan perundang-undangan. Ketika terjadi konflik dalam hal unsur materiil di kemudian hari terkait aset kripto sebagai jamaninan dalam perjanjian pinjaman dana maka akibat hukum yang dapat timbul adalah gugatan oleh pihak yang telah dirugikan.

In the antenna array synthesis problems, most of the works in literature utilize isotropic elements. Thus, the mutual coupling effects between the array elements are neglected. It is obvious that an array antenna synthesized by neglecting the coupling effects cannot be used in the real world applications due to the possible mismatch between the desired and realized radiation patterns. In this paper, a novel method based on neural network algorithm RBF (Radial Basis Function ) for the synthesis and model of Antipodal Vivaldi antenna with mutual coupling effect is presented. The synthesis in implementation’s method for this type of array permits to approach the appropriated radiation pattern while considering the mutual coupling between its elements. The neural network is used to estimate the array elements’ excitations. The architecture of the neural network based on the radial basis functions (RBFs) is introduced and simulation results are presented. Results show that there is an agreement between the desired specifications and the synthesized one. The proposed optimization approach offers an efficient and robust synthesis procedure.

Introduction: Medical evacuation in general is characterized by the need for the rapid transfer of a patient from one medical centre to another more equipped or better specialized. Obstetric emergencies are multiple causes of maternal and neonatal death. Purpose: Was to study the reasons for reference / medical evacuation obstetrical at the Reference Health Center of Commune V of the District of Bamako. Materials and Methods: This was a descriptive study with a retrospective collection from January 1, 2017 to December 31, 2020. Results: We collected 4280 referrals/evacuations out of 28974 admissions; or 14.8% of admissions. The median age was 26.17 years. Housewives accounted for 45.4%. Dystocia was the main reason for references/evacuations with 41.1%. The reasons for referral/evacuation were consistent in 60.3% of cases. These evacuations were relevantin 21.8%. Maternal mortality was 0.8%. Conclusion: Evacuations accounted for 14.8% (4280) of deliveries. The most commonly cited reasons were dystocia, antepartum haemorrhage and high blood pressure and its complications. Dystocia, fetal asphyxia and high blood pressure and its complications were the main diagnoses.

Introduction: It is estimated that 60 to 80% of women in developing countries continue to give birth at home without any assistance or with the help of unskilled people and usually in an unsanitary environment. Purpose: It was tostudy unassisted home birth in two districts of Commune V. Materials and Methods: This was a prospective, crosssectional and analytical study from 1 March 2019 to 28 February 2020. Results: We recorded 263 home deliveries or 13% of deliveries in Sabalibougou and 62 home deliveries or 3% of deliveries in Badalabougou. The proportion of women not attending school was 74.64% in Sabalibougou against 25.36% in Badalabougou. In Sabalibougou, 89.40% of women had given birth at home due to lack of financial means compared to 10.60% in Badalabougou. Haemorrhage by uterine atony was the most represented complication in the two districts, 72.92% in Sabalibougou and 27.08% in Badalabougou.