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Your search keyword '"Cucurachi, L."' showing total 5 results
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5 results on '"Cucurachi, L."'

1. Risk of disease relapse, safety and tolerability of SARS-CoV-2 vaccination in patients with chronic inflammatory neuropathies

Author

Doneddu, P. E., Briani, C., Cocito, D., Manganelli, F., Fabrizi, G. M., Matà, S., Mazzeo, A., Fazio, R., Benedetti, L., Luigetti, M., Inghilleri, M., Ruiu, E., Siciliano, G., Cosentino, G., Marfia, G. A., Carpo, M., Filosto, M., Antonini, G., Notturno, F., Sotgiu, S., Cucurachi, L., Dell'Aquila, C., Bianchi, E., Rosso, T., Giordano, A., Fernandes, M., Campagnolo, M., Peci, E., Spina, E., Tagliapietra, M., Sperti, M., Gentile, L., Strano, C., Germano, F., Romozzi, M., Moret, F., Zarbo, I. R., Viola, D. V., Vegezzi, E., Mataluni, G., Cotti-Piccinelli, S., Leonardi, L., Carta, A., and Nobile-Orazio, E.

Subjects
COVID-19, SARS-CoV-2, chronic inflammatory demyelinating polyneuropathy, multifocal motor neuropathy, vaccination, Settore MED/26
Published
2023

2. Alcohol intake and the risk of intracerebral hemorrhage in the elderly: The MUCH-Italy

Author

Costa, P., Grassi, M., Iacoviello, L., Zedde, M., Marcheselli, S., Silvestrelli, G., Delodovici, M. L., Sessa, M., Zini, A., Paciaroni, M., Azzini, C., Gamba, M., Del Sette, M., Toriello, A., Gandolfo, C., Bonifati, D. M., Tassi, R., Cavallini, A., Chiti, A., Calabro, R. S., Grillo, F., Bovi, P., Tomelleri, G., Di Castelnuovo, A., Ritelli, M., Agnelli, G., De Vito, A., Pugliese, N., Martini, G., Lodigiani, C., Morotti, A., Poli, L., Degiuli, V., Caria, F., Cornali, C., Degaetano, G., Colombi, M., Padovani, A., Pezzini, A., D'Amore, C., Acciarresi, M., Caso, V., Alberti, A., Venti, M., Vandelli, L., Dell'Acqua, M. L., Simone, A. M., Nichelli, P. F., Lanari, A., Ciccone, A., Del Zotto, E., Gilberti, N., Magoni, M., Zucco, G., Massucco, D., Finocchi, C., Balestrino, M., Carletti, M., Zivelonghi, C., Casella, C., La Spina, P., Musolino, R., Bramanti, P., Princiotta Cariddi, L., Giorli, E., Strambo, D., Giacalone, G., Glielmi, A., Volpe, G., Micieli, G., Montano, V., Padroni, Marotta, G., Malferrari, G., Marcello, N., Cucurachi, L., and Giossi, A.

Subjects
Male, medicine.medical_specialty, Alcohol Drinking, Alcohol, Intracerebral hemorrhage, Elderly, 03 medical and health sciences, 0302 clinical medicine, Elderly, Risk Factors, Internal medicine, medicine, 80 and over, Humans, cardiovascular diseases, 030212 general & internal medicine, Prospective Studies, Prospective cohort study, Aged, Cerebral Hemorrhage, Intracerebral hemorrhage, Aged, 80 and over, business.industry, Case-control study, Case-Control Studies, Female, Italy, Middle Aged, Self Report, Odds ratio, medicine.disease, Confidence interval, nervous system diseases, Cohort, Alcohol intake, Observational study, Neurology (clinical), business, Alcohol, 030217 neurology & neurosurgery
Abstract

ObjectiveTo investigate the role of alcohol as a causal factor for intracerebral hemorrhage (ICH) and whether its effects might vary according to the pathogenic mechanisms underlying cerebral bleeding.MethodsWe performed a case-control analysis, comparing a cohort of consecutive white patients with ICH aged 55 years and older with a group of age- and sex-matched stroke-free controls, enrolled in the setting of the Multicenter Study on Cerebral Haemorrhage in Italy (MUCH-Italy) between 2002 and 2014. Participants were dichotomized into excessive drinkers (>45 g of alcohol) and light to moderate drinkers or nondrinkers. To isolate the unconfounded effect of alcohol on ICH, we used causal directed acyclic graphs and the back-door criterion to select a minimal sufficient adjustment set(s) of variables for multivariable analyses. Analyses were performed on the whole group as well as separately for lobar and deep ICH.ResultsWe analyzed 3,173 patients (1,471 lobar ICH and 1,702 deep ICH) and 3,155 controls. After adjusting for the preselected variables in the minimal sufficient adjustments, heavy alcohol intake was associated with deep ICH risk (odds ratio [OR], 1.68; 95% confidence interval [CI], 1.36–2.09) as well as with the overall risk of ICH (OR, 1.38; 95% CI, 1.17–1.63), whereas no effect was found for lobar ICH (OR, 1.01; 95% CI, 0.77–1.32).ConclusionsIn white people aged 55 years and older, high alcohol intake might exert a causal effect on ICH, with a prominent role in the vascular pathologies underlying deep ICH.

Published
2018

4. Migraine improvement after spontaneous cervical artery dissection the Italian Project on Stroke in Young Adults (IPSYS)

Author

Filomena Caria, Corrado Lodigiani, Enrico Maria Lotti, Francesca Graziano, Elisa Giorli, Andrea Zini, Lucia Tancredi, Maurizio Paciaroni, Valeria Piras, Massimiliano Braga, Valeria De Giuli, Mario Grassi, Ilaria Casetta, Maria Luisa DeLodovici, Loris Poli, Simona Marcheselli, Laura Cucurachi, Alessandro Pezzini, Rosalba Patella, Alessandro Padovani, Alessandro Adami, Massimo Gamba, Carmela Casella, Alessia Giossi, Giorgio Silvestrelli, Marialuisa Zedde, De Giuli, V, Graziano, F, Zini, A, Zedde, M, Patella, R, Lodigiani, C, Marcheselli, S, Delodovici, M, Paciaroni, M, Casetta, I, Giorli, E, Adami, A, Braga, M, Casella, C, Giossi, A, Silvestrelli, G, Tancredi, L, Lotti, E, Poli, L, Caria, F, Piras, V, Cucurachi, L, Gamba, M, Grassi, M, Padovani, A, and Pezzini, A

Subjects
Adult, Male, Migraine without Aura, medicine.medical_specialty, Neurology, Aura, Migraine with Aura, Remission, Spontaneous, LS5_11, Dermatology, Cervical artery dissection, Cervical artery dissection, Migraine, Stroke in young adults, 03 medical and health sciences, Young Adult, Economica, Stroke in young adults, 0302 clinical medicine, Risk Factors, Internal medicine, Medicine, Humans, 030212 general & internal medicine, Young adult, Stroke, Migraine, LS4_7, Vertebral Artery Dissection, business.industry, Migraine. Spontaneus cervical dissection, General Medicine, Pain scale, Cerebral Infarction, medicine.disease, Migraine with aura, Stroke in young, Psychiatry and Mental health, adults Migraine, Italy, Case-Control Studies, Female, Neurology (clinical), medicine.symptom, Headaches, business, 030217 neurology & neurosurgery
Abstract

Objective: Whether migraine modifies after spontaneous cervical artery dissection (sCeAD) more than after other stroke etiologic subtypes has never been adequately investigated. Methods: In the setting of the Italian Project on Stroke in Young Adults (IPSYS), we compared the course of migraine before and after acute brain infarct in a group of migraine patients with sCeAD and a group of migraine patients whose ischemia was due to a cause other than CeAD (non-CeAD IS), matched by sex, age (± 3 years), and migraine subtype.We applied linear mixed models to evaluate pre-event vs post-event changes and differences between sCeAD and non-CeAD IS patients. Results: Eighty-seven patients per group (migraine without aura/migraine with aura, 67/20) qualified for the analysis. After the acute event, migraine headaches disappeared in 14.0% of CeAD patients vs 0.0% of non-CeAD IS patients (p ≤ 0.001). Migraine frequency (patients suffering at least 1 attack, from 93.1 to 80.5%, p = 0.001), pain intensity (from 6.7 ± 1.7 to 4.6 ± 2.6 in a 0 to 10 pain scale, p ≤ 0.001), and use of acute anti-migraine medications (patients taking at least 1 preparation, from 81.6 to 64.4%, p = 0.007) also improved significantly after CeAD as opposed to that observed after non-CeAD IS. Conclusion: The spontaneous improvement of migraine after sCeAD reinforces the hypothesis of a pathogenic link between the two conditions

Published
2019

5. A novel homozygous PLA2G6 mutation causes dystonia-parkinsonism

Author

Sara Bonato, Edoardo Monfrini, Giulia Franco, Davide Donner, G. Monzio Compagnoni, Mafalda Rizzuti, Paola Feraco, D. Orrico, L. Cucurachi, Ilaria Trezzi, A. Di Fonzo, E. Di Biase, Stefania Corti, P. Fortis, Linda Borellini, Dario Ronchi, Maria Chiara Malaguti, Valentina Melzi, R. Di Giacopo, Nereo Bresolin, Giacomo P. Comi, Malaguti, M.C., Melzi, V., Di Giacopo, R., Monfrini, E., Di Biase, E., Franco, G., Borellini, L., Trezzi, I., Compagnoni, G.M., Fortis, P., Feraco, P., Orrico, D., Cucurachi, L., Donner, D., Rizzuti, M., Ronchi, D., Bonato, S., Bresolin, N., Corti, S., Comi, G.P., and Di Fonzo, A.

Subjects
Adult, PLAN, Parkinsonism, Bioinformatics, PLA2G6, DNA Mutational Analysi, Group VI Phospholipases A2, Medicine, Parkinson's disease genetic, Dystonia, Family Health, NBIA, business.industry, Parkinson Disease, medicine.disease, Magnetic Resonance Imaging, Corpus Striatum, Substantia Nigra, Neurology, Rapid onset, Mutation (genetic algorithm), Mutation, Female, Neurology (clinical), Geriatrics and Gerontology, business, Human
Abstract

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Published
2015

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