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We present the ionised gas outflow morphology in the Circinus galaxy using the Narrow Field Mode (NFM) of the MUSE instrument on board the Very Large Telescope (VLT). The NFM observations provide a spatial resolution of $\sim$0.1", corresponding to a physical scale of $\sim$2 pc, one of the highest spatial resolution achievable using ground-based AO-assisted observations in the optical wavelengths. The MUSE observations reveal a collimated clumpy outflow profile originating near the AGN location and extending up to 1.5" ($\sim$30 pc) in the NW direction. The collimated structure then fragments into two filaments, giving the entire outflowing gas a ``tuning-fork'' morphology. These structures remain undetected in the lower spatial resolution MUSE Wide Field Mode data. We explain the origin of this tuning-fork structure to the interaction of the outflow with a dense clump in the interstellar medium (ISM) as the outflow propagates outward. The origin of the collimated structure itself could be from jet-ISM interactions on small scales. These observations also provide evidence to the origin of the ionised gas filaments previously observed in the Circinus galaxy out to kiloparsec scales. We find instantaneous and time-averaged mass outflow rates of 10$^{-2}$ M$_{\odot}$ yr$^{-1}$ and 10$^{-4}$ M$_{\odot}$ yr$^{-1}$, respectively. Based on the star formation rate in the Circinus galaxy reported in the literature, the observed ionised outflows are not expected to regulate star formation within the $\sim$100 pc scales probed by the NFM data., 8 pages, 8 figures; accepted for publication in MNRAS

A total of 606 sows (PIC 1050) and their progeny (PIC 1050 × 280) were used to determine if feeding gestating and lactating sows a proprietary strain of Pichia guilliermondii as a whole-cell inactivated yeast product (WCY; CitriStim, ADM Animal Nutrition, Quincy, IL) improves sow and litter performance in a commercial production system. Once confirmed pregnant at d 35 post-breeding pregnancy check, sows were fed a basal gestation control (CON) diet (0.55% SID lysine) or the control diet fortified with 0.15% of the WCY replacing corn in the CON diet. Dietary treatments were also fed in lactation (1.05% SID lysine) once sows were moved into farrowing crates on approximately d 112 of gestation until weaning. Sows supplemented with WCY in gestation and lactation had increased total born piglets by 0.45 pigs (P < 0.04), piglets born alive (14.27 vs. 13.85; P < 0.04), and, therefore, heavier born alive litter weights (P < 0.001) compared to CON fed sows. A greater post cross-foster litter size (P < 0.001) meant that litter size at weaning was increased by 0.54 pigs when sows were fed WCY compared to CON (P < 0.001). However, litter weaning weights and 21-d adjusted litter weaning weights were similar (P > 0.158), although numerically greater, for WCY fed sows. Pigs from CON fed sows were 0.35 kg heavier at weaning compared to pigs from WCY fed sows (P < 0.001). This increase in weaning weight of pigs from CON fed sows is partially explained by their 0.93 d longer lactation (P < 0.001) and may also be due to the smaller litter size throughout lactation. The percent of litters treated for scours decreased from 38.3 to 14.2% when sows were fed WCY (P < 0.001). The distribution of birth and weaning weights was not impacted (P > 0.2461) by treatment. In conclusion, feeding gestating and lactating sows a proprietary strain of Pichia guilliermondii as a whole-cell inactivated yeast product increased the number of pigs born and weaned, and decreased the prevalence of scours during lactation.

Mixed sex pigs (n = 720) were placed in 12 rooms (Purdue Swine Environmental Research Building) to measure the effect of reduced crude protein (CP), amino acid (AA)-supplemented diets on growth and the carcass. Pigs were blocked by body weight (BW) and gender and allotted to room and pen (10 mixed-sex pigs/pen). Pigs were fed a nine-phase, wean-finish program. Control pigs consumed corn-soybean meal-distiller’s dried grains with solubles (DDGS) diets containing no to minimal (Met) synthetic AA. The 2X diet was formulated to meet the seventh most-limiting AA, and balanced using synthetic AAs to meet all AA needs. The 1X diet was formulated to meet a CP value halfway between the control and 2X diet, and also balanced using synthetic AAs to meet all AA needs. Diets were formulated to identical net energy concentrations and balanced to meet standard ileal digestible NRC 2012 AA requirements. Pit vacuum samples were collected at the end of each growth phase for analyses of nitrogen, C and dry matter (DM). Pigs fed the Control and 1X diet grew faster (P < 0.005), had greater gain:feed (P < 0.001), and were heavier at market (P < 0.001) than animals fed the 2X diet. No consistent effects of diet were observed on average daily feed intake. Carcass data were analyzed for sex, diet and sex*diet effects. Reductions in dietary CP resulted in a linear reduction in ammonium nitrogen excretion per kg of BW gain in Nursery (P < 0.001) and Grow-Finish (P < 0.001) phases. Reductions in dietary CP, with synthetic AA supplementation resulted in a linear reduction in total nitrogen excreted per kg BW gain in the Grow-Finish phase (P < 0.001) and overall (P < 0.001). Total mineral excretion per kg gain was reduced in pigs fed 1X and 2X diets compared with control-fed pigs (P < 0.005). Reductions in dietary CP of ~3 and 5%-units from wean-finish result in reductions of total N excretion of 11.7 and 24.4%, respectively. Reduced performance and carcass characteristics observed in pigs fed the 2X diets indicates an inaccurate estimate of NRC 2012 AA requirements or ratios to lysine in a low CP diet.

A developmental Bacillus based direct-fed microbial (DFM) was added to nursery pig diets to evaluate the effect on growth and health in two 35-d randomized complete block design experiments blocked on initial BW and sex. Experiment 1 used 315 weaned pigs (20.1 d of age; 6.11 kg initial BW) allotted to one of three diets: 1) Negative Control (NC; no antibiotics but with pharmacological Zn or Cu), 2) NC+DFM 0.55x109CFU, 3) NC+DFM 1.1x109CFU. Experiment 2 used 376 weaned pigs (17.8 d of age; 5.99 kg initial BW) allotted to one of four diets, the same 3 diets from Experiment 1 plus a lower inclusion rate: 4) NC+DFM 0.275x109CFU. Both studies had 15 replicates/treatment, 6–7 pigs/pen. Pigs were budget fed phase 1–3 diets (1.13 kg/pig; 2.72 kg/pig; and 6.35 kg/pig, respectively) and ad libitum fed Phase 4 diet to d35. For Experiment 1, during week 1 pigs fed the DFM tended to linearly decrease ADFI (P = 0.086) and linearly increase G:F (P = 0.085). During day 21–35 of Experiment 1 pigs fed DFM linearly increased ADG (P = 0.035) and quadratically increased ADFI (P = 0.027). Overall for experiment 1, ADG (P = 0.114) and ADFI (P = 0.104) tended to quadratically increase and G:F linearly increased (P = 0.012) with increasing concentrations of DFM. Experiment 2; during week 1 and 3 ADFI (P = 0.084, P = 0.050, respectively) quadratically increased and G:F (P = 0.081; P = 0.022, respectively) quadratically decreased as DFM increased in the diet. During d21–35 of experiment 2, ADG (P = 0.064) quadratically increased and G:F (P = 0.012) quadratically decreased as DFM increased. Overall for Experiment 2 ADFI numerically increased (4.3%) with no increase in ADG, resulting in a quadratic decrease in G:F (P = 0.010) as the DFM increased in the diet. Summarizing these two studies, the DFM product had its greatest effect increasing ADFI while inconsistently impacting gain and efficiency.

A total of 606 sows (PIC 1050) and their progeny (PIC 1050×280) were used to determine if feeding gestating and lactating sows a proprietary strain of Pichia guilliermondi as a whole-cell inactivated yeast product (WCY; CitriStim, ADM Animal Nutrition, Quincy, IL) improves sow and litter performance in a commercial production system. Once confirmed pregnant at d 35 post-breeding pregnancy check, sows were fed either a basal gestation control (CON) diet (0.55% SID Lysine) or the control diet fortified with 0.15% (1.36 kg/ton) of the WCY replacing corn in the CON diet. Dietary treatments were also fed in lactation (1.05% SID Lysine) once sows were moved into farrowing crates on approximately d 112 of gestation until weaning. Sows supplemented with WCY in gestation and lactation had a greater number of total born piglets by 0.45 pigs (P=0.040), born alive (P< 0.04), heavier born alive litter weight (P< 0.001), and greater post cross-foster litter size (P< 0.001) compared to CON fed sows. Litter size at weaning was increased by 0.54 pigs when sows were fed WCY compared to CON (P< 0.001). However, the average piglet weaning weights from CON fed sows were heavier by 0.35 kg compared to WCY (P< 0.001). This increase in body weight of piglets from CON fed sows is partially explained by their 0.93 days longer lactation (P< 0.001), and may also be due to the smaller litter size nursed throughout lactation. The percent of litters treated for scours decreased from 38.3% to 14.2% when sows were fed WCY (P< 0.001). The distribution of birth weights by body weight range was not different (P=0.2461) between treatments. In conclusion, feeding gestating and lactating sows a proprietary strain of Pichia guilliermondi as a whole-cell inactivated yeast product increased the number of piglets born and number weaned as well as decreased the prevalence of scours during lactation.

Forty-seven sows and their progeny were used to determine if feeding gestating and lactating sows a Bacillus licheniformis direct-fed microbial (DFM), an organic acid blend of medium chain and short chain fatty acids (OA), or in combination improves sow lactation feed and water intake, litter growth, and subsequent reproductive performance. On approximately d80 of gestation, sows were fed one of four diets in a 2 x 2 factorial design: 1) gestation control (CON; 0.55% SID Lysine), 2) CON with DFM (1.6x109 CFU/kg of complete feed), 3) CON with 0.4% OA, 4) CON with both DFM and OA. Dietary treatments were also fed throughout lactation (1.00% SID Lysine) starting on approximately d112 of gestation when sows entered farrowing facility. There was a tendency (P = 0.079) for DFM to decrease the amount of sow body weight loss in lactation by approximately 6% compared to sows not consuming the DFM, likely related to DFM sows numerically (P = 0.124) consuming 8.4% more feed during d7-14 of lactation. Sows fed the OA diets had fewer mummies/litter (P = 0.038) compared to diets not containing OA. Sows fed diets with the DFM gave birth to lighter pigs born alive (P = 0.003) compared to non-DFM fed sows, and a tendency for an interaction (P = 0.092) existed where feeding OA+DFM lessened the decrease in born alive BW. There was an interaction tendency (P = 0.133) where sows fed DFM returned to estrus 22 hours sooner than CON, but only 8 hours sooner when sows were fed the OA+DFM diet. In conclusion, feeding a Bacillus licheniformis DFM to sows may decrease pig born alive weight but reduce sow BW loss through 6.4% more lactation feed intake, quickening the return to estrus. Feeding the OA alone or in combination did not improve sow reproductive and litter growth performance in this study, and may require a larger sample size.

The objective of this study was to evaluate the effects of total or partial replacement of animal and fish proteins with a fortified protein blend (PROPLEX MVP) on growth performance of nursery piglets. PROPLEX MVP is a blend of two distinct fermentation biomass streams, refined soybean products, select amino acids, and a NSP enzyme complex. A total of 306 barrows and gilts [(Duroc x (Landrace x Yorkshire), avg. 22 d age and BW 6.37 ± 1.24 kg)] were used in a randomized complete block design with three dietary treatments, each with 19 replicates (pens) of 5 piglets. Dietary treatments were: 1) Control diet (CONT) with animal and fish protein sources (Blood meal, Spray-dried Plasma, and Fish meal); 2) PROPLEX MVP (MVP): CONT with MVP replacing Fish meal; 3) PROPLEX MVP 100 (MVP100): CONT with MVP replacing 100% of animal and fish proteins. Pigs were fed a budgeted amount per head of the assigned experimental diets for the first three feeding phases (Phase 1: 2.3 kg/pig; Phase 2: 4.5 kg/pig; Phase 3: 6.8 kg/pig). A common diet was provided in Phase 4 until day 42 post-weaning. Pigs fed CONT had greater ADG (P < 0.05) compared to MVP100 pigs d 0-7 post-weaning. From d 7 to 14, pigs fed MVP and MVP100 had a significantly greater ADG and G:F (P < 0.05) than pigs fed CONT diet. For the remainder of the experimental period (d 14 to 42), no differences (P > 0.10) were observed among treatments. The use of MVP100 reduced (P < 0.05) the total nursery feed cost by US $1.03/pig and feed cost/kg of weight gain by 12%. In conclusion, MVP protein blend can effectively substitute for animal and fish proteins sources without compromising overall nursery pigs’ growth performance and results in significant feed cost savings.

Progeny from sows fed diets containing a Bacillus licheniformis direct-fed microbial (DFM), an organic acid blend of medium and short chain fatty acids (OA), DFM+OA, or a control (CON) diet from d80 of gestation until weaning were used to determine if feeding CON, DFM, OA, or DFM+OA to the dam and/or progeny post-weaning improved nursery growth performance. Weaned pigs from 47 dams (n = 384, Initial BW=6.15 kg) were blocked by initial BW and sex and allotted (6 pigs/pen, 8 pens/treatment) to one of 8 nursery treatments. Pigs from CON sows were fed a negative (NC; no antibiotics, pharmacological Zn or Cu) or positive [PC; Neo-Terramycin phases 1 and 2 (827 and 551 ppm) and Carbadox phase 3 (55 ppm)] control diet. Pigs from sows fed DFM, OA, or DFM+OA were fed the NC diet or a diet representative of their dam. Diets with DFM contained 1.6x109 CFU/kg DFM and diets with OA contained 0.5, 0.4, and 0.3% OA in phases 1–3, respectively. Weaning weight was used as a covariate for nursery performance. For all phases and overall, PC fed pigs had greater ADG, ADFI, and G:F (P < 0.05). Feeding DFM or OA in sow diets improved (interaction; P< 0.042) nursery pig G:F, but DFM+OA offspring had no improvement for d7–14, 0–14, and 0–21 G:F. Feeding DFM or OA to sows and their progeny decreased ADFI (interaction; P < 0.042) but improved G:F (interaction; P < 0.028) for d7–14 and 0–14 with DFM+OA having no improvement above CON. For d14–21 and 0–21, feeding DFM or OA to sows and their progeny decreased ADFI whereas DFM+OA increased ADFI above CON (interaction; P < 0.019). In conclusion, feeding DFM or OA to sows or their offspring may improve nursery feed efficiency and feeding DFM+OA diet to sows and their progeny may increase ADFI late in the nursery period.

A total of 535 sows and their progeny (PIC 359×1050) were used to determine the effect of feeding gestating and lactating sows a proprietary strain of Pichia guilliermondi as a whole-cell inactivated yeast product (WCY; CitriStim, ADM Animal Nutrition, Quincy, IL) on sow and litter performance in a commercial production system. Within 24 hours of breeding, sows were allotted to 1 of 2 dietary treatments. Parity distribution was equalized across treatments. Sows were fed either a basal gestation control (CON) diet or CON fortified with 0.1% (0.91 kg/ton) of the WCY at the expense of corn throughout gestation. Sow dietary treatments were also maintained through lactation. Of the 535 sows that completed the initial reproductive cycle (cycle 1), 358 sows were maintained on dietary treatment and followed through a second gestation and lactation (cycle 2). The direction and magnitude of the differences in total born and born alive pigs in cycle 1 and cycle 2 was similar between treatments. Supplementing sows with WCY in cycle 1 increased the number of total born pigs by 0.59 pigs/litter (P=0.038) and tended to increase the number of pigs born alive by 0.52 pigs/litter (P=0.064) compared to CON fed sows. For cycle 2, the total number of born and born alive pigs numerically increased by 0.44 pigs/litter (P=0.180) and 0.43 pigs/litter (P=0.179) respectively for sows fed WCY. The distribution of pig birth weights was not different between treatments in cycle 1 (P=0.536) nor cycle 2 (P=0.256). Also, the litter growth rate on a weight gain per pig per day basis was not different between treatments in cycle 1 (P=0.103) nor cycle 2 (P=0.379). In conclusion, feeding gestating and lactating sows a proprietary strain of Pichia guilliermondi as a whole-cell inactivated yeast product significantly increased the number of total born pigs during cycle 1.

This experiment observed the effects of replacing animal and fish proteins with a fortified protein blend (PROPLEX MVP) on growth performance, immune status, microbial metabolites, and fecal scoring of nursery pigs. A total of 244 barrows and gilts [Duroc x (Landrace x Yorkshire), avg. 19 d age and BW 5.88 ± 1.38 kg] were used in a 2 × 2 factorial design (2 dietary treatments × 2 feeding programs). The dietary treatments were: 1) Control diet (CONT) with animal and fish proteins and 2) PROPLEX MVP (MVP100): CONT with MVP replacing 100% of the animal and fish proteins. The feeding programs for each feeding phase were: high budget (H): Phase 1: 2.3 kg/pig; Phase 2: 4.5 kg/pig; Phase 3: 6.8 kg/pig and low budget (L): Phase 1: 1.1 kg/pig; Phase 2: 2.3 kg/pig; Phase 3: 3.4 kg/pig). For d 0-7, pigs fed CONT had greater ADG, ADFI, and G:F (P < 0.001) compared to MVP100. From d 7 to 14, ADG and G:F were greater (P < 0.05) for pigs fed MVP100 compared to CONT pigs and greater for pigs fed the H budget compared to the L budget (P < 0.05). Overall, d 0 to 35, there were no differences (P > 0.05) in pig final BW, overall ADG, and G:F. For week two and most of the experimental period, pigs fed CONT had greater (P < 0.05) fecal scores, more soft and watery feces, and increased diarrhea incidence compared to MVP100 pigs. The total concentration of fecal volatile fatty acids was greater (P < 0.05) in CONT compared to MVP100 fed pigs. In conclusion, the MVP protein blend can be used as a cost effective alternative to animal and fish proteins in nursery pig diets without compromising overall growth performance, immune status, and post-weaning diarrhea.

Hot, Dust-Obscured Galaxies (Hot DOGs), selected from the WISE all sky infrared survey, host some of the most powerful Active Galactic Nuclei (AGN) known, and might represent an important stage in the evolution of galaxies. Most known Hot DOGs are at $z> 1.5$, due in part to a strong bias against identifying them at lower redshift related to the selection criteria. We present a new selection method that identifies 153 Hot DOG candidates at $z\sim 1$, where they are significantly brighter and easier to study. We validate this approach by measuring a redshift $z=1.009$, and an SED similar to higher redshift Hot DOGs for one of these objects, WISE J1036+0449 ($L_{\rm\,Bol}\simeq 8\times 10^{46}\rm\,erg\,s^{-1}$), using data from Keck/LRIS and NIRSPEC, SDSS, and CSO. We find evidence of a broadened component in MgII, which, if due to the gravitational potential of the supermassive black hole, would imply a black hole mass of $M_{\rm\,BH}\simeq 2 \times 10^8 M_{\odot}$, and an Eddington ratio of $\lambda_{\rm\,Edd}\simeq 2.7$. WISE J1036+0449 is the first Hot DOG detected by NuSTAR, and the observations show that the source is heavily obscured, with a column density of $N_{\rm\,H}\simeq(2-15)\times10^{23}\rm\,cm^{-2}$. The source has an intrinsic 2-10 keV luminosity of $\sim 6\times 10^{44}\rm\,erg\,s^{-1}$, a value significantly lower than that expected from the mid-infrared/X-ray correlation. We also find that the other Hot DOGs observed by X-ray facilities show a similar deficiency of X-ray flux. We discuss the origin of the X-ray weakness and the absorption properties of Hot DOGs. Hot DOGs at $z\lesssim1$ could be excellent laboratories to probe the characteristics of the accretion flow and of the X-ray emitting plasma at extreme values of the Eddington ratio., Comment: Accepted for publication in ApJ, 16 pages

A total of 1,360 pigs were used in a 125-d study to determine the effects of corn dried distillers grains with solubles (DDGS) withdrawal after immunological castration (Improvest, Zoetis, Kalamazoo, MI) on growth performance and carcass fat quality of pigs. Pens of male pigs (initially 24 kg) were randomly allotted by BW and castration method (physically castrated [PC] or immunologically castrated [IC] barrows) to 1 of 3 diets with 8 replications per treatment and 27 to 29 pigs per pen. Treatments were arranged in a 2 × 3 factorial with main effects of castration method and diet (0% DDGS throughout, 30% DDGS throughout, or 30% DDGS through d 75 then no DDGS to d 125). Intact males were injected with Improvest on d 39 and 74 (IC). No castration method × diet interactions (P > 0.12) were observed for growth performance. Before the second Improvest injection (d 0 to 74), PC barrows had increased (P < 0.05) ADFI but were less efficient (P < 0.05) than intact males. After the second Improvest injection until the first marketing event (d 74 to 107), IC barrows had improved (P < 0.05) ADG and G:F compared with PC barrows. From d 0 to 107, IC barrows had improved (P < 0.05) ADG, G:F, and lower ADFI than PC barrows. The inclusion of 30% DDGS decreased (P < 0.05) G:F compared with pigs fed the control diet. For the period after the second Improvest injection (d 74 to 125), IC barrows had increased (P < 0.05) ADG, ADFI, and G:F compared with PC barrows. Overall (d 0 to 125), IC barrows had improved (P < 0.05) ADG and G:F and lower ADFI than PC barrows. The inclusion of 30% DDGS decreased (P < 0.05) G:F. Carcass yield was lower (P < 0.05) for IC than PC barrows. Pigs fed 30% DDGS throughout had decreased (P < 0.05) carcass yield; however, withdrawing DDGS from the diet on d 74 was effective at fully recovering the yield loss. Carcass fat iodine values (IV) were consistently higher (P < 0.05), regardless of fat depot or harvest time when 30% DDGS were included in the diet. Multiple 2-way interactions (P < 0.05) were detected between castration method, DDGS, depot, and time. Interactions were a result of fatty acid profiles changing more rapidly in backfat and belly fat than in jowl fat from d 107 to 125 and more dramatically in IC than PC barrows in the same period. This improvement from d 107 to 125 could be caused by the dilution of unsaturated fatty acids, specifically C18:2 and C18:3, due to rapid deposition of fat from de novo synthesis in IC barrows.

A total of 264 pigs (initially 41.0 kg BW) were used in a 90-d study to determine the effects of lowering dietary fiber before market on pigs fed high dietary fiber [provided by wheat middlings (midds) and distillers dried grains with solubles (DDGS)] on growth performance, carcass characteristics, carcass fat quality, and intestinal weights of growing-finishing pigs. Pens of pigs were randomly allotted by initial BW and sex to 1 of 6 treatments with 6 replications per treatment and 7 or 8 pigs per pen. A positive control (corn-soybean meal-based) diet containing no DDGS or midds (9.3% NDF) and a negative control diet with 30% DDGS and 19% midds (19% NDF) were fed throughout the entire trial (d 0 to 90). The other 4 treatments were arranged in a 2 × 2 factorial with the main effects of length of fiber reduction (23 or 47 d before marketing) and fiber level fed during the reduction period (low or medium). Pigs on these treatments were fed the negative control before the reduction treatment. The medium-fiber diet contained 15% DDGS and 9.5% midds (14.2% NDF) with the low-fiber diet was the positive control diet. Increasing the feeding duration of the low-fiber diets lowered overall ADFI (linear, P = 0.03) and improved G:F (linear, P < 0.01). Lowering the fiber level for the last 23 d did not influence growth performance; however, lowering the fiber level improved carcass yield (P = 0.002), with a greater response (P < 0.001) when the low-fiber diet was fed for 23 d. Jowl fat iodine value (IV) decreased when the longer lower fiber diets were fed (linear, P < 0.01) and was lower (P < 0.001) for pigs fed the low-fiber diet during the fiber reduction period than pigs fed the medium-fiber diet during the same time period; however, increasing the time lower fiber diets were fed from 23 to 47 d further reduced (P < 0.01) jowl IV. Increasing the duration that the control diet was fed by increasing the reduction time from 23 to 47 d increased (P < 0.01) backfat depth. Reducing the fiber level decreased full large intestine weight (linear, P = 0.005) with a greater response (P = 0.04) when the low-fiber diet was fed during the reduction period instead of the medium-fiber diet. In summary, lowering the fiber level before marketing can improve G:F, carcass yield, carcass IV, and reduce large intestine weight; however, the optimal duration of the fiber reduction period depends on the targeted response criteria.

In an attempt to study whether the formation of brown dwarfs (BDs) takes place as a scaled-down version of low-mass stars, we conducted IRAM30m/MAMBO-II observations at 1.2 mm in a sample of 12 proto-BD candidates selected from Spitzer/IRAC data in the B213-L1495 clouds in Taurus. Subsequent observations with the CSO at 350 micron, VLA at 3.6 and 6 cm, and IRAM30m/EMIR in the 12CO(1-0), 13CO(1-0), and N2H+(1-0) transitions were carried out toward the two most promising Spitzer/IRAC source(s), J042118 and J041757. J042118 is associated with a compact (

A total of 36 pigs (PIC 337 × 1050; initially 185 lb BW) were used in a 14-d study to evaluate the effects of xylanase (Porzyme 9302; Danisco Animal Nutrition, St. Louis, MO) in growing-finishing diets varying in dietary fiber on nutrient digestibility. Pigs were randomly allotted to 1 of 6 dietary treatments in a 2 × 3 factorial. Main effects were increasing dried distillers grains with solubles (DDGS; 35, 42.5, and 50%) with or without xylanase (0 or 4,000 units xylanase per kilogram of diet. The 6 treatment diets were corn-soybean meal–based with 15% added wheat middlings (midds), with 6 replications per treatment. All diets were fed in meal form. Multiple enzyme × DDGS interactive effects (P < 0.05) were observed for digestibility of various nutrients. The majority of these interactions resulted from differences in response to increasing DDGS with and without xylanase. In diets with xylanase, apparent digestibility generally decreased as DDGS increased. In diets without xylanase, apparent digestibility decreased as DDGS increased from 35 to 42.5% but increased in diets containing 50% DDGS. Overall, despite the interactions, increasing DDGS regardless of enzyme inclusion lowered (quadratic, P < 0.01) apparent fecal digestibility of DM, GE, ADF, NDF, and zinc as well as fecal digestibility (linear, P < 0.02) of fat, Ca, and P. Despite the interactions, adding dietary xylanase did not improve digestibility in corn-soybean meal–based diets containing fibrous co-products.

A total of 264 pigs (PIC 327 × 1050, initially 90.1 lb) were used in a 90-d study to determine the effects of withdrawal of high dietary NDF (provided by wheat middlings [midds] and dried distillers grains with solubles [DDGS]) on growth performance, carcass characteristics, carcass fat quality, and intestinal weights of growing-finishing pigs. Pens of pigs were randomly allotted by initial weight and gender to 1 of 6 dietary treatments with 6 replications per treatment. There were 24 pens with 7 pigs per pen (3 barrows and 4 gilts) and 12 pens with 8 pigs per pen (4 barrows and 4 gilts). A positive control diet containing no DDGS or midds and a negative control diet containing 30% DDGS and 19% midds was fed the entire study duration (no withdrawal). The other 4 treatments were arranged in a 2 × 2 factorial with the main effects of withdrawal time (23 or 47 d) and NDF level fed during the withdrawal (low or medium). Pigs on these treatments were fed the negative control diet containing 30% DDGS and 19% wheat midds (19% NDF) prior to their withdrawal treatment. The medium fiber withdrawal diet contained 15% DDGS and 9.5% midds (14.2% NDF). The low-fiber withdrawal diet was the positive control diet without DDGS or midds (9.3% NDF). Increasing the duration of the withdrawal lowered overall ADFI (linear, P 0.61) growth performance. Withdrawing the high-fiber diet improved carcass yield (P < 0.004) with a greater response (P < 0.001) when the low-NDF diet was fed during the withdrawal instead of the medium NDF diet; however, increasing the withdrawal time from 23 to 47 d did not further improve yield (P = 0.11).

It is time for the United States to rethink its policy toward the European Union and European integration more broadly. The new challenges of the twenty-first century and America's changing priorities and strategic needs are making America more rather than less dependent on the European Union and its success. The United States' ability to reach its own top foreign policy objectives – defending the US homeland, winning the war on terror and promoting the spread of freedom and democracy around the world – increasingly require a strong, politically cohesive and outward-looking Europe that can act as a partner around the world. Today America needs a functioning EU as much as an effective NATO.

This article argues that the Atlanticism of Central and Eastern Europe originates in a specific set of historical experiences these countries have had with the United States over the past century. These include the Central and East European encounter with both Nazi and communist totalitarian regimes; a recognition of the leading role the US played in toppling communism and in facilitating the integration of these countries into Euro-Atlantic institutions; and the strategic calculation of many countries in the region that their national interests in Europe are better preserved via active American engagement that balances the influence of other major European powers.

Western governments have thus far struggled to translate bold rhetoric into a realistic and plausible strategy that can help promote democracy and human development in the broader Middle East. Such a strategy should be based on these three pillars.

NATO's Enlargement: Past, Present and Future, by Ronald D. Asmus During the 1990s, NATO's enlargement became a constant of American foreign policy. It was intended to do for the Eastern half of Europe what the Alliance has done for the Western half: to deploy a security umbrella for the reinforcement of democracy and the facilitation of intégration. These twin aims gave rise to some of the most profound changes in American thinking on Europe and NATO: while maintaining their engagement in NATO for collective security, the United States are encouraging it to adopt a new strategie concept which makes the defense of western values and interests a priority, even beyond the immediate frontiers of the West. The strength of this vision is confirmed by the Senate's ratification of the Alliance's enlargement, in 1998. But the September 11 attacks change the state of play: by reinforcing the U.S.' interest in the consolidation of peace in Europe, by reinvigorating the executive's role in the conduct of foreign policy and by eliminating the risk of a confrontation with Russia, the enlargement issue has been over-taken by questions relating to the role and the organisation of the Alliance in the face of new threats., Dans les années 1990, l'élargissement de l'OTAN devient l'un des piliers de la politique étrangère des Etats-Unis ; il doit permettre de faire pour la moitié orientale de l'Europe ce que l'Alliance a contribué à faire pour sa moitié occidentale : déployer un parapluie de sécurité pour renforcer la démocratie et favoriser l'intégration. Cette double visée donne lieu à certains des changements les plus profonds de la réflexion des Etats-Unis sur l'Europe et l'OTAN : tout en maintenant l'engagement de celle-ci en matière de défense collective, les Etats-Unis la poussent à adopter un nouveau concept stratégique privilégiant la défense des valeurs et des intérêts occidentaux, au-delà de ses frontières immédiates. La force de cette vision est confirmée par la ratification de l'élargissement de l'Alliance par le sénat, en 1998. Mais les attentats du 11 septembre modifient la donne : en renforçant l'intérêt des Etats-Unis pour la consolidation de la paix en Europe, en revigorant le rôle de l'exécutif américain dans la conduite de la politique étrangère et en faisant disparaître le risque d'une confrontation avec la Russie, ils substituent à la question de l'élargissement celle de la finalité et de l'organisation de l'Alliance face aux nouvelles menaces., Asmus, Cochez Marie-Aude. L'élargissement de l'OTAN : passé, présent, futur. In: Politique étrangère, n°2 - 2002 - 67ᵉannée. pp. 353-376.

A total of 1,360 pigs were used in a 125-d study to determine the effects of corn dried distillers grains with solubles (DDGS) withdrawal after immunological castration (Improvest, Zoetis, Kalamazoo, MI) on growth performance and carcass fat quality of pigs. Pens of male pigs (initially 24 kg) were randomly allotted by BW and castration method (physically castrated [PC] or immunologically castrated [IC] barrows) to 1 of 3 diets with 8 replications per treatment and 27 to 29 pigs per pen. Treatments were arranged in a 2 × 3 factorial with main effects of castration method and diet (0% DDGS throughout, 30% DDGS throughout, or 30% DDGS through d 75 then no DDGS to d 125). Intact males were injected with Improvest on d 39 and 74 (IC). No castration method × diet interactions (P0.12) were observed for growth performance. Before the second Improvest injection (d 0 to 74), PC barrows had increased (P0.05) ADFI but were less efficient (P0.05) than intact males. After the second Improvest injection until the first marketing event (d 74 to 107), IC barrows had improved (P0.05) ADG and G:F compared with PC barrows. From d 0 to 107, IC barrows had improved (P0.05) ADG, G:F, and lower ADFI than PC barrows. The inclusion of 30% DDGS decreased (P0.05) G:F compared with pigs fed the control diet. For the period after the second Improvest injection (d 74 to 125), IC barrows had increased (P0.05) ADG, ADFI, and G:F compared with PC barrows. Overall (d 0 to 125), IC barrows had improved (P0.05) ADG and G:F and lower ADFI than PC barrows. The inclusion of 30% DDGS decreased (P0.05) G:F. Carcass yield was lower (P0.05) for IC than PC barrows. Pigs fed 30% DDGS throughout had decreased (P0.05) carcass yield; however, withdrawing DDGS from the diet on d 74 was effective at fully recovering the yield loss. Carcass fat iodine values (IV) were consistently higher (P0.05), regardless of fat depot or harvest time when 30% DDGS were included in the diet. Multiple 2-way interactions (P0.05) were detected between castration method, DDGS, depot, and time. Interactions were a result of fatty acid profiles changing more rapidly in backfat and belly fat than in jowl fat from d 107 to 125 and more dramatically in IC than PC barrows in the same period. This improvement from d 107 to 125 could be caused by the dilution of unsaturated fatty acids, specifically C18:2 and C18:3, due to rapid deposition of fat from de novo synthesis in IC barrows.

A total of 264 pigs (initially 41.0 kg BW) were used in a 90-d study to determine the effects of lowering dietary fiber before market on pigs fed high dietary fiber [provided by wheat middlings (midds) and distillers dried grains with solubles (DDGS)] on growth performance, carcass characteristics, carcass fat quality, and intestinal weights of growing-finishing pigs. Pens of pigs were randomly allotted by initial BW and sex to 1 of 6 treatments with 6 replications per treatment and 7 or 8 pigs per pen. A positive control (corn-soybean meal-based) diet containing no DDGS or midds (9.3% NDF) and a negative control diet with 30% DDGS and 19% midds (19% NDF) were fed throughout the entire trial (d 0 to 90). The other 4 treatments were arranged in a 2 × 2 factorial with the main effects of length of fiber reduction (23 or 47 d before marketing) and fiber level fed during the reduction period (low or medium). Pigs on these treatments were fed the negative control before the reduction treatment. The medium-fiber diet contained 15% DDGS and 9.5% midds (14.2% NDF) with the low-fiber diet was the positive control diet. Increasing the feeding duration of the low-fiber diets lowered overall ADFI (linear, P = 0.03) and improved G:F (linear, P0.01). Lowering the fiber level for the last 23 d did not influence growth performance; however, lowering the fiber level improved carcass yield (P = 0.002), with a greater response (P0.001) when the low-fiber diet was fed for 23 d. Jowl fat iodine value (IV) decreased when the longer lower fiber diets were fed (linear, P0.01) and was lower (P0.001) for pigs fed the low-fiber diet during the fiber reduction period than pigs fed the medium-fiber diet during the same time period; however, increasing the time lower fiber diets were fed from 23 to 47 d further reduced (P0.01) jowl IV. Increasing the duration that the control diet was fed by increasing the reduction time from 23 to 47 d increased (P0.01) backfat depth. Reducing the fiber level decreased full large intestine weight (linear, P = 0.005) with a greater response (P = 0.04) when the low-fiber diet was fed during the reduction period instead of the medium-fiber diet. In summary, lowering the fiber level before marketing can improve G:F, carcass yield, carcass IV, and reduce large intestine weight; however, the optimal duration of the fiber reduction period depends on the targeted response criteria.

The rehearsals began on 1 September 1976, and the premiere was on 1 October 1976. The rehearsals were in the morning between 10:00 a.m. and 2:00 p.m. , about half the time being devoted each day to each piece. Beckett had already staged both pieces in London early in the same year. In London he had worked with Billie Whitelaw in Footfalls. They knew one another very well, and right from the start the rehearsals had gone ahead in an atmosphere of mutual understanding and intuitive sympathy. In Berlin, Beckett was confronted with an actress whom he didn't know in the part of May, an actress whose work in the theater was based on the search for realistic, concrete motivations and who was not willing or not able automatically to work in an intuitively structural way. The rehearsals therefore evolved in an atmosphere of productive questioning on the part of the actress and of respect on the part of Beckett for the striving of a very talented actress to perfect her role by constantly seeking, in her own way, for access to the characteristics of the “strange, mysterious” figure of May.

In the OH radical-induced oxidation of cyclo-Met-Met an OH adduct,cyclo-Met-Met(S∴OH), absorbing at γmax = 390 nm with e390cyclo-Met-Met(S∴OH) = 4500 dm3 mol−1 cm−1 is formed. This adduct reversibly eliminates hydroxide ion, pKb = 5.4 ± 0.1, forming corresponding (S ∴ S)-bonded radical cation, cyclo-Met-Met(S ∴ S)+, which absorbs at γmax = 510 nm with e510cyclo-Met-Met(S ∴ S)+ = 6200 ± 400 dm3 mol-1 cm-1. The OH- elimination is catalysed by H+ and buffers. The rate constants are k=(1.4 ± 0.1)×109dm3mol−1s−1 and k=(1.0±0.1)×104s−1 for the H+ catalysed and uncatalysed reactions, respectively. The rate constant for the reverse reaction is k[cyclo-Met-Met(S ∴ S)+ + OH-] = (2.6 ± 0.3) × 109 dm3 mol-1 s-1. A certain amount of cyclo-Met-Met(S |.: S)+, G ≈ 1, is formed immediately after the pulse, independently of the actual equilibrium position. Therefore, the existence of at least two different precursors of the cyclo-Met-Met(S ∴ S)+ is inferred.