28 results on '"Gui, Na"'
Search Results
2. Assessment of the embolization effect of temperature-sensitive p(N-isopropylacrylamide-co-butyl methylacrylate) nanogels in the rabbit renal artery by CT perfusion and confirmed by macroscopic examination
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Yanbing Zhao, Zhen Zhang, Kun Qian, Ping Han, Gui-Na Ma, Nanchuan Jiang, Xin Zhang, Hongsen Zhang, Li Han, Yan Chen, Chuansheng Zheng, and Chunyuan Cen
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medicine.medical_treatment ,Science ,Nanogels ,Perfusion scanning ,Article ,030218 nuclear medicine & medical imaging ,03 medical and health sciences ,0302 clinical medicine ,Renal Artery ,medicine.artery ,medicine ,Animals ,Embolization ,Right Renal Artery ,Renal artery ,Kidney ,Multidisciplinary ,business.industry ,Temperature ,Collateral circulation ,Embolization, Therapeutic ,Perfusion ,medicine.anatomical_structure ,Renal blood flow ,Nanoparticles ,Medicine ,Rabbits ,Nuclear medicine ,business ,Tomography, X-Ray Computed ,X-ray tomography ,030217 neurology & neurosurgery - Abstract
Transcatheter embolization is an important treatment method in clinical therapy, and vascular embolization material plays a key role in embolization. The temperature-sensitive p(N-isopropylacrylamide-co-butyl methylacrylate) (PIB) nanogel is a novel embolic agent. To evaluate the feasibility of the nanogel as a blood vessel embolization agent, we aimed to assess the effect of embolization with PIB nanogels in the rabbit renal artery by non-invasive computed tomography (CT) perfusion, macroscopic and histological examination. Ten healthy adult Japanese rabbits were used to implement RAE of PIB nanogels in their right kidneys. CT perfusion scans were performed pre- and post-treatment at various time-points (1, 4, 8, and 12 weeks). Two rabbits were euthanized and histologically examined at each time-point, and the remaining rabbits were euthanized at 12 weeks after embolization. The RAE efficacy of the nanogels was further confirmed by macroscopic and histological examination. The renal volume and renal blood flow (BF) of the right kidney were significantly decreased post-treatment compared with those pre-treatment (volume: pre, 9278 ± 1736 mm3; post 1 week, 5155 ± 979 mm3, P 3, P 3, P 3, P P P P P
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- 2021
3. Relationship between pancreatic parenchyma loss and early postoperative hyperglycemia in patients with benign pancreatic diseases
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Hongli Yang, Ping Han, Gui-Na Ma, Xiaofei Yue, Yu Zhang, Chunyuan Cen, Mengting Huang, Xin Li, Kan Wen, and Lei-Di Wu
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Pancreatic parenchyma ,medicine.medical_specialty ,Urology ,Pancreatic surgery ,Remnant pancreatic volume ,Pancreatic endocrine insufficiency ,Gastroenterology ,Benign tumor ,03 medical and health sciences ,Pancreatectomy ,Postoperative Complications ,Diabetes mellitus ,0302 clinical medicine ,Internal medicine ,medicine ,Humans ,Radiology, Nuclear Medicine and imaging ,In patient ,Pancreas ,Radiological and Ultrasound Technology ,business.industry ,Pancreatic Diseases ,Hepatology ,medicine.disease ,Pancreatic Neoplasms ,Partial Pancreatectomy ,Hyperglycemia ,030220 oncology & carcinogenesis ,CT imaging ,Pancreatitis ,030211 gastroenterology & hepatology ,Preoperative fasting ,business - Abstract
Objective To evaluate the relationship between pancreatic parenchyma loss and early postoperative hyperglycemia in patients with benign pancreatic diseases. Methods A total of 171 patients with benign pancreatic tumors or chronic pancreatitis, whose preoperative fasting blood glucose (FBG) was normal and who underwent partial pancreatectomy were reviewed. The pancreatic volume was measured by CT imaging before and after the operation. According to their different pancreatic resection volume (PRV), 171 patients were divided into five groups: < 30%, 30%–39%, 40%–49%, 50%–59%, and ≥ 60%. The correlation between the PRV and postoperative FBG was investigated. According to the postoperative FBG value, the patients were divided into a hyperglycemia group (HG) and nonhyperglycemia group (non-HG) to explore the best cutoff value of the PRV between the two groups. Results There were significant differences in the postoperative FBG among the five groups (PRV < 30%, 30%–39%, 40%–49%, 50%–59%, and ≥ 60%). The PRV was positively correlated with postoperative FBG in the benign tumor group and chronic pancreatitis group (R = 0.727 and 0.651, respectively). ROC curve analysis showed that the best cutoff value of the PRV between the HG (n = 84) and non-HG (n = 87) was 39.95% with an AUC = 0.898; the sensitivity was 89.29%, and the specificity was 82.76%. Conclusion There was a linear positive correlation between the postoperative FBG level and PRV. Patients with a PRV ≥ 40% are more likely to develop early postoperative hyperglycemia.
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- 2021
4. Author Correction: Image Quality and Radiation Dose for Prospectively Triggered Coronary CT Angiography: 128-Slice Single-Source CT versus First-Generation 64-Slice Dual-Source CT
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Ping Han, Gui-Na Ma, Sheng Wu, Jin Gu, Heshui Shi, and Jie Yu
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Male ,Image quality ,Computed Tomography Angiography ,Science ,Dual source ct ,Coronary Artery Disease ,Radiation Dosage ,Heart Rate ,Medicine ,Humans ,Author Correction ,Aged ,Multidisciplinary ,business.industry ,Radiation dose ,Coronary ct angiography ,Middle Aged ,Image Enhancement ,Coronary Vessels ,First generation ,Radiographic Image Interpretation, Computer-Assisted ,Female ,business ,Nuclear medicine - Abstract
This study sought to compare the image quality and radiation dose of coronary computed tomography angiography (CCTA) from prospectively triggered 128-slice CT (128-MSCT) versus dual-source 64-slice CT (DSCT). The study was approved by the Medical Ethics Committee at Tongji Medical College of Huazhong University of Science and Technology. Eighty consecutive patients with stable heart rates lower than 70 bpm were enrolled. Forty patients were scanned with 128-MSCT, and the other 40 patients were scanned with DSCT. Two radiologists independently assessed the image quality in segments (diameter1 mm) according to a three-point scale (1: excellent; 2: moderate; 3: insufficient). The CCTA radiation dose was calculated. Eighty patients with 526 segments in the 128-MSCT group and 544 segments in the DSCT group were evaluated. The image quality 1, 2 and 3 scores were 91.6%, 6.9% and 1.5%, respectively, for the 128-MSCT group and 97.6%, 1.7% and 0.7%, respectively, for the DSCT group, and there was a statistically significant inter-group difference (P ≤ 0.001). The effective doses were 3.0 mSv in the 128-MSCT group and 4.5 mSv in the DSCT group (P ≤ 0.001). Compared with DSCT, CCTA with prospectively triggered 128-MSCT had adequate image quality and a 33.3% lower radiation dose.
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- 2020
5. Interface water-induced hydrophobic carbon chain unfolding in water
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Qing Liang, Gui-Na Wei, Zheng Li, Jianlong Kou, Gang Lou, Jiang-Xing Chen, and Zhang Xie
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Carbon chain ,Materials science ,Physics and Astronomy (miscellaneous) ,Chemical engineering ,Interface (Java) ,Electric field - Abstract
The folding and unfolding of the carbon chain, which is the basic constitutional unit of polymers, are important to the performance of the material. However, it is difficult to regulate conformational transition of the carbon chain, especially in an aqueous environment. In this paper, we propose a strategy to regulate the conformational transition of the carbon chain in water based on the all-atom molecular dynamics simulations. It is shown that the unfolded carbon chain will spontaneously collapse into the folded state, while the folded carbon chain will unfold with an external electric field. The regulation ability of the electric field is attributed to the electric field-induced redistribution of interface water molecules near the carbon chain. The demonstrated method of regulating conformational transition of the carbon chain in water in this study provides an insight into regulating hydrophobic molecules in water, and has great potential in drug molecule design and new polymer material development.
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- 2021
6. Rapid and Sensitive Detection of Malachite Green and Melamine with Silver Film over Nanospheres by Surface-Enhanced Raman Scattering
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Gui-Na Xiao, Zhuo-Hui Li, and Wen-Bin Huang
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Detection limit ,Materials science ,Scanning electron microscope ,010401 analytical chemistry ,Biophysics ,Analytical chemistry ,Substrate (chemistry) ,02 engineering and technology ,Sputter deposition ,021001 nanoscience & nanotechnology ,01 natural sciences ,Biochemistry ,0104 chemical sciences ,symbols.namesake ,chemistry.chemical_compound ,chemistry ,symbols ,Thin film ,0210 nano-technology ,Raman spectroscopy ,Melamine ,Raman scattering ,Biotechnology - Abstract
Silver film over nanospheres (AgFON) have been prepared by depositing Ag thin film onto the self-assembled monolayer arrays of polystyrene nanospheres with vacuum magnetron sputtering method. The surface morphologies and optical properties have been characterized by using scanning electron microscope (SEM) and ultraviolet-visible near-infrared (UV-Vis-NIR) spectrophotometer. AgFON was used as substrate to detect the surface-enhanced Raman scattering (SERS) spectra of malachite green (MG) and melamine (MA). It was found that the AgFON substrate presented outstanding performance that the Raman enhancement factor was calculated to be as large as 9.76 × 1012. The minimum limit for MG was down to 10−8 mol/L with a good linear response range from 10−4 to 10−8 mol/L. In addition, this substrate showed excellent ability to recognize MA molecules with a detection limit of 0.1 mg/L. A good linearity (r = 0.9887) was obtained in the concentration range of 2–100 mg/L. Furthermore, the AgFON substrate exhibited good uniformity with a relative standard deviation (RSD) of 9.01 % and good reproducibility with RSD of 8.60 %.
- Published
- 2016
7. Killer Cell Immunoglobulin-Like Receptor Genes and their HLA-C Ligands in Hashimoto Thyroiditis in a Chinese Population
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Yong-qing Wei, Gui-na Yu, Jin Xu, Yan-feng Hou, Hui Sun, Yulian Jiao, Ming-feng Cao, Yiqing Liu, Jiajun Zhao, Yueran Zhao, Jian-ting Li, Cheng Guo, Li Feng, Haiqing Zhang, Minglong Li, Bingchang Zhang, and Ling Gao
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Adult ,Male ,0301 basic medicine ,China ,Endocrinology, Diabetes and Metabolism ,Killer-cell immunoglobulin-like receptor ,HLA-C Antigens ,Hashimoto Disease ,Human leukocyte antigen ,Ligands ,law.invention ,03 medical and health sciences ,HLA-C ,0302 clinical medicine ,Endocrinology ,Asian People ,Gene Frequency ,Receptors, KIR ,law ,Genotype ,Humans ,Medicine ,Genetic Predisposition to Disease ,Receptor ,Allele frequency ,Polymerase chain reaction ,business.industry ,General Medicine ,Middle Aged ,030104 developmental biology ,Case-Control Studies ,Immunology ,Female ,business ,030215 immunology - Abstract
Natural killer (NK) cells serve as primary immune surveillance and are partially regulated by combinations of killer immunoglobulin-like receptors (KIR) and their human leukocyte antigen-C (HLA-C) ligands. Alterations in NK cell activity have been associated with Hashimoto thyroiditis (HT). The aim of this study was to determine whether certain KIR/HLA-C genotype combinations play a role in HT pathogenesis.The present study enrolled 107 unrelated HT patients and 108 random healthy individuals in a case-control study. Blood was collected for DNA extraction; typing of KIR genes and HLA-C alleles was performed by polymerase chain reaction with sequence specific primers (PCR-SSP), followed by electrophoresis on agarose gels.Among a panel of KIR2D/HLA-C genotype combinations, the frequency of KIR2DS2/HLA-C1 was significantly increased in HT patients compared to controls (33.64% vs. 12.96%, P.001). To further analyze the precise genotype, we investigated inhibitory or activating KIR/HLA-C gene pairs when their corresponding activating or inhibitory KIR genes were absent in the 2 groups. Only the frequency of KIR2DS2(-)2DL2/3(+)HLA-C1(+) was significantly decreased in HT patients compared to controls (48.60% vs. 70.37%, P = .001).Our data suggest that KIR2DS2/HLA-C1 may correlate with HT pathogenesis. On the contrary, the predominance of KIR2DL2/3/HLA-C1 in the absence of KIR2DS2 suggests a potential inhibitory role in HT pathogenesis. In conclusion, our findings may further elucidate the mechanisms underlying the pathogenesis of HT and other autoimmune diseases.HLA-C = human leukocyte antigen-C HT = Hashimoto thyroiditis KIR = killer immunoglobulin-like receptor NK = natural killer PCR = polymerase chain reaction.
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- 2016
8. Surface-enhanced Raman scattering activities of gold nanocap arrays and hollow gold nanocap particles
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Gui-Na Xiao, Jie Gao, Shi-Qing Man, Xin Le, Hai-Tao Zhang, Yun-Xiang Li, and Tian-Xiong Wu
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Chemistry ,Scanning electron microscope ,Sonication ,Analytical chemistry ,02 engineering and technology ,Substrate (electronics) ,010402 general chemistry ,021001 nanoscience & nanotechnology ,01 natural sciences ,Atomic and Molecular Physics, and Optics ,0104 chemical sciences ,Analytical Chemistry ,symbols.namesake ,Colloid ,Transmission electron microscopy ,symbols ,Surface plasmon resonance ,0210 nano-technology ,Dissolution ,Spectroscopy ,Raman scattering - Abstract
Gold (Au) nanocap arrays and hollow gold nanocap particles were prepared by dip-coating technique combined with wet chemical reduction method, and followed by sonication and dissolution of the silica colloidal template. The surface morphologies and optical properties of the obtained samples were characterized by scanning electron microscopy, transmission electron microscope, and ultraviolet-visible spectrophotometer, respectively. Gold nanocap arrays and hollow gold nanocap particles were used as substrates to detect the surface-enhanced Raman scattering spectra of malachite green and methylene blue (MB), respectively. It was found that the gold nanocap arrays had higher enhancement ability than hollow gold nanocap particles, with enhancement factor of 1.3 × 105 and 3.5 × 103, respectively. In addition, gold nanocap arrays exhibited excellent reproducibility with a relative standard deviation of less than 5% and about 10% across a single substrate and between different substrates, respectively. Th...
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- 2016
9. Self-Assembly of Dimer Motors under Confined Conditions*
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Zhou-Ting Jiang, Gui-Na Wei, Li-Yan Qiao, An Zhou, and Ye-Hua Zhao
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Nanostructure ,Materials science ,Field (physics) ,Dimer ,General Physics and Astronomy ,02 engineering and technology ,021001 nanoscience & nanotechnology ,01 natural sciences ,Catalysis ,chemistry.chemical_compound ,Monomer ,chemistry ,Chemical physics ,0103 physical sciences ,Volume fraction ,Self-assembly ,010306 general physics ,0210 nano-technology ,Concentration gradient - Abstract
Chemically synthetic nanomotors can consume fuel in the environment and utilize the self-generated concentration gradient to self-propel themselves in the system. We study the collective dynamics of an ensemble of sphere dimers built from linked catalytic and noncatalytic monomers. Because of the confinement from the fuel field and the interactions among motors, the ensemble of dimer motors can self-organize into various nanostructures, such as a radial pattern in the spherical fuel field and a staggered radial pattern in a cylindrical fuel field. The influence of the dimer volume fraction on the self-assembly is also investigated and the formed nanostructures are analyzed in detail. The results presented here may give insight into the application of the self-assembly of active materials.
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- 2020
10. Influence of Surface Topographical Modifications of Titanium Implants on Bone Cell Responses
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Gui, Na
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- 2018
- Full Text
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11. Pancreatic neuroendocrine neoplasms: Correlation between MR features and pathological tumor grades
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Xin Li, Ting-ting Qin, Ping Han, Kai Wang, Feng Guo, Feng Jin, Gui-na Ma, and Xue-han Hu
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Adult ,Male ,medicine.medical_specialty ,Pathology ,Adolescent ,Biomedical Engineering ,Neuroendocrine tumors ,Biochemistry ,Sensitivity and Specificity ,030218 nuclear medicine & medical imaging ,Metastasis ,Biomaterials ,03 medical and health sciences ,Young Adult ,0302 clinical medicine ,Genetics ,medicine ,Humans ,Stage (cooking) ,Pathological ,Aged ,Pancreatic duct ,Neoplasm Grading ,medicine.diagnostic_test ,business.industry ,Magnetic resonance imaging ,Middle Aged ,medicine.disease ,Magnetic Resonance Imaging ,Pancreatic Neoplasms ,Neuroendocrine Tumors ,medicine.anatomical_structure ,Lymphatic system ,ROC Curve ,030220 oncology & carcinogenesis ,Female ,Radiology ,business - Abstract
This study investigated the accuracy of MRI features in differentiating the pathological grades of pancreatic neuroendocrine neoplasms (PNENs). A total of 31 PNENs patients were retrospectively evaluated, including 19 cases in grade 1, 5 in grade 2, and 7 in grade 3. Plain and contrastenhanced MRI was performed on all patients. MRI features including tumor size, margin, signal intensity, enhancement patterns, degenerative changes, duct dilatation and metastasis were analyzed. Chi square tests, Fisher's exact tests, one-way ANOVA and ROC analysis were conducted to assess the associations between MRI features and different tumor grades. It was found that patients with older age, tumors with higher TNM stage and without hormonal syndrome had higher grade of PNETs (all P
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- 2017
12. The Effect of L-Cysteine on Surface-Enhanced Raman Scattering of Malachite Green in Silver Colloids
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Gui-Na Xiao and Shi-Qing Man
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Detection limit ,Chemistry ,digestive, oral, and skin physiology ,Inorganic chemistry ,Nanoparticle ,Photochemistry ,Atomic and Molecular Physics, and Optics ,Silver nanoparticle ,Analytical Chemistry ,symbols.namesake ,Colloid ,chemistry.chemical_compound ,symbols ,Molecule ,Malachite green ,Spectroscopy ,Raman scattering ,Cysteine - Abstract
Colloidal silver nanoparticles were prepared by a simple chemical reduction method. The effect of L-cysteine on the surface-enhanced Raman scattering activity of colloidal silver nanoparticles was investigated by using malachite green as a probe molecule. It was found that the surface-enhanced Raman scattering activity of colloidal silver nanoparticles was improved tremendously with the help of L-cysteine. The possible reasons for this enhancement effect were given. Specifically, in silver colloidal solution, no surface-enhanced Raman scattering spectrum of malachite green was observed at a relatively low concentration (≤2.5 × 10−5 mol/L). However, well-resolved and high-quality surface-enhanced Raman scattering spectra of malachite green were successfully obtained after the addition of L-cysteine to silver colloids, and the minimum detection limit for malachite green was down to 10−8 mol/L.
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- 2013
13. Image Quality and Radiation Dose for Prospectively Triggered Coronary CT Angiography: 128-Slice Single-Source CT versus First-Generation 64-Slice Dual-Source CT
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Sheng Wu, Gui-Na Ma, Jin Gu, Heshui Shi, Jie Yu, and Ping Han
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medicine.medical_specialty ,Multidisciplinary ,medicine.diagnostic_test ,Image quality ,business.industry ,Radiation dose ,Dual source ct ,Coronary computed tomography angiography ,Coronary ct angiography ,030204 cardiovascular system & hematology ,medicine.disease ,Article ,First generation ,030218 nuclear medicine & medical imaging ,Coronary artery disease ,03 medical and health sciences ,0302 clinical medicine ,medicine ,Radiology ,business ,Computed tomography angiography - Abstract
This study sought to compare the image quality and radiation dose of coronary computed tomography angiography (CCTA) from prospectively triggered 128-slice CT (128-MSCT) versus dual-source 64-slice CT (DSCT). The study was approved by the Medical Ethics Committee at Tongji Medical College of Huazhong University of Science and Technology. Eighty consecutive patients with stable heart rates lower than 70 bpm were enrolled. Forty patients were scanned with 128-MSCT, and the other 40 patients were scanned with DSCT. Two radiologists independently assessed the image quality in segments (diameter >1 mm) according to a three-point scale (1: excellent; 2: moderate; 3: insufficient). The CCTA radiation dose was calculated. Eighty patients with 526 segments in the 128-MSCT group and 544 segments in the DSCT group were evaluated. The image quality 1, 2 and 3 scores were 91.6%, 6.9% and 1.5%, respectively, for the 128-MSCT group and 97.6%, 1.7% and 0.7%, respectively, for the DSCT group, and there was a statistically significant inter-group difference (P ≤ 0.001). The effective doses were 3.0 mSv in the 128-MSCT group and 4.5 mSv in the DSCT group (P ≤ 0.001). Compared with DSCT, CCTA with prospectively triggered 128-MSCT had adequate image quality and a 33.3% lower radiation dose.
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- 2016
- Full Text
- View/download PDF
14. Hypertonic glucose pleurodesis and surgical diaphragmatic repair for tension hydrothorax complicating continuous ambulatory peritoneal dialysis
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Gui-Na Wei and Jian-Hua Mao
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Adult ,Male ,medicine.medical_specialty ,medicine.medical_treatment ,Diaphragm ,Hydrothorax ,Diaphragmatic breathing ,Thoracentesis ,030204 cardiovascular system & hematology ,030230 surgery ,Pleuroperitoneal ,Peritoneal dialysis ,03 medical and health sciences ,0302 clinical medicine ,Peritoneal Dialysis, Continuous Ambulatory ,Glucose Solution, Hypertonic ,medicine ,Humans ,Pleurodesis ,business.industry ,Thoracic Surgery, Video-Assisted ,Continuous ambulatory peritoneal dialysis ,General Medicine ,medicine.disease ,Surgery ,Nephrology ,Anesthesia ,Kidney Failure, Chronic ,Hemodialysis ,business - Abstract
We herein describe a case of tension hydrothorax that occurred on continuous ambulatory peritoneal dialysis (CAPD), highlighting the problems of diagnosis and a novel management. A 38-year-old male with end-stage renal disease (ESRD) due to diabetes mellitus developed dyspnea and poor drainage after 13 months of CAPD. Chest X-ray revealed massive right-sided hydrothorax and mediastinal shift. He underwent emergency thoracentesis and pleural fluid showed a high level of glucose. Pleuroperitoneal communication was strongly suspected, although the methylene blue test was negative. We temporarily performed hemodialysis. Two weeks later, PD was resumed but failed with recurrent right-side hydrothorax in 4 months. The pleuroperitoneal leakage was definitively confirmed by video-assisted thoracoscopic surgery (VATS). Diaphragmatic repair and pleurodesis with hypertonic glucose were performed. There was no recurrence of hydrothorax after treatment.
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- 2016
15. Synthesis of bismuth nanocap arrays on quartz substrates and their surface plasmon resonance properties
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Shi-Qing Man and Gui-Na Xiao
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Diffraction ,Materials science ,Absorption spectroscopy ,Infrared ,Scanning electron microscope ,Analytical chemistry ,chemistry.chemical_element ,General Chemistry ,Condensed Matter Physics ,Bismuth ,chemistry ,Transmission electron microscopy ,Monolayer ,General Materials Science ,Surface plasmon resonance - Abstract
Bismuth nanocap arrays have been prepared by vacuum depositing Bi films onto the surfaces of self-assembled monolayer arrays of SiO2 nanoparticles. The surface morphologies, structures, and optical properties of the obtained samples have been characterized by transmission electron microscopy (TEM), scanning electron microscopy (SEM), atomic force microscope (AFM), X-ray diffraction (XRD), and ultraviolet–visible–near infrared (UV–vis–NIR) spectrophotometer. TEM and AFM images indicated that the SiO2/Bi composite nanoparticles were incompletely encapsulated and their surfaces were relatively rough. UV–vis–NIR absorption spectra showed that Bi nanocap arrays had strong and tunable surface plasmon resonance peaks in the visible and near infrared regions, which were dependent dramatically on the relative ratio of the SiO2 core diameter to the Bi cap thickness.
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- 2012
16. PREPARATION AND SURFACE PLASMON RESONANCE OF COPPER NANOCAP ARRAYS
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Gui-Na Xiao, Hua-Li Zhang, Yan-Xiao Feng, and Shi-Qing Man
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Diffraction ,Materials science ,Scanning electron microscope ,business.industry ,Atomic force microscopy ,Analytical chemistry ,chemistry.chemical_element ,Statistical and Nonlinear Physics ,Condensed Matter Physics ,Copper ,Evaporation (deposition) ,Core (optical fiber) ,Optics ,chemistry ,Surface plasmon resonance ,business ,Absorption (electromagnetic radiation) - Abstract
Copper nanocap arrays, consisting of a SiO 2 core with a Cu cap, were prepared by chemical synthesis combined with physical evaporation technique. The obtained samples were characterized by scanning electron microscopy, atomic force microscopy, X-ray diffraction, and ultraviolet-visible-near-infrared spectrophotometer. The copper nanocap arrays were found to exhibit tunable surface plasmon resonance (SPR) absorption peaks that were red-shifted as the ratio of the SiO 2 core diameter to the Cu cap thickness increased. While the cap thickness varied between 20 nm and 50 nm, the SPR peak shifted from 1650 nm to 1230 nm. While the core diameter varied between 140 nm and 400 nm, the longitudinal SPR peak shifted from 1243 nm to 1830 nm.
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- 2011
17. The effect of magnetic nanoparticles of Fe3O4 on immune function in normal ICR mice
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Gui-Na Zhou, Jia-Hua Ding, Chong Gao, Yue Chen, Xiaomao Li, Baoan Chen, Men Tang, Jun Wang, Xuemei Wang, Nan Jin, Guohua Xia, Yu Zhang, Jian Cheng, Feng Gao, and Yin Zhou
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CD4-Positive T-Lymphocytes ,Male ,medicine.medical_specialty ,medicine.medical_treatment ,Biophysics ,Pharmaceutical Science ,Bioengineering ,Spleen ,magnetic nanoparticle of Fe3O4 ,Biology ,CD8-Positive T-Lymphocytes ,Lymphocyte Activation ,Flow cytometry ,Biomaterials ,Mice ,Immune system ,Microscopy, Electron, Transmission ,International Journal of Nanomedicine ,Immunity ,Internal medicine ,Drug Discovery ,medicine ,Splenocyte ,cytokine ,Animals ,Particle Size ,Magnetite Nanoparticles ,Saline ,Original Research ,immune function ,Mice, Inbred ICR ,medicine.diagnostic_test ,Dose-Response Relationship, Drug ,splenocyte proliferation ,Organic Chemistry ,General Medicine ,Endocrinology ,medicine.anatomical_structure ,Cytokine ,Nanomedicine ,Immunology ,Cytokines ,Female ,CD8 - Abstract
Bao-An Chen1, Nan Jin1, Jun Wang1, Jiahua Ding1, Chong Gao1, Jian Cheng1, Guohua Xia1, Feng Gao1, Yin Zhou1, Yue Chen1, Guina Zhou1, Xiaomao Li2, Yu Zhang3, Men Tang3, Xuemei Wang31Department of Hematology, Zhongda Hospital, Clinical Medical School, Southeast University, Nanjing, People’s Republic of China; 2Department of Physics, University of Saarland, D-266041 Saarbruechen, Germany; 3National Key Laboratory of Bioelectronics (Chien-Shiung Wu Laboratory), Southeast University, Nanjing, People’s Republic of ChinaAbstract: We investigated the effect of magnetic nanoparticles of Fe3O4 (Fe3O4-MNPs) on the mice immune system. Imprinting control region (ICR) mice were assigned randomly into four groups and treated with normal saline or low, medium, or high doses of Fe3O4-MNPs, respectively. After intravenous administration of Fe3O4-MNPs for 72 hours, the peripheral T cells and the induction of primary immune responses in mice were investigated by flow cytometry and determined using enzyme-linked immunosorbent assay, respectively. The results showed that the ratio of spleen to body weight was not different between the experimental groups and control group (P > 0.05). The lymphocyte transformation rates in the suspension of spleen were higher in low-dose group than those in the control group (P < 0.05), while the proliferation of splenocytes was low in the medium and high groups when compared to the control group (P < 0.05). In peripheral blood, both the proportions of subset CD4+ and CD8+ T lymphocytes in the low-dose group were higher than those in the control group, whereas there was no difference in the number of CD4+ T cells between the medium- and low-dose groups. Interestingly, the Fe3O4-MNPs enhanced the production of interleukin-2 (IL-2), interferon-γ, and IL-10 but did not affect the production of IL-4 in peripheral blood. It is concluded that Fe3O4-MNPs could influence immune functions of normal ICR mice in a dose-dependent manner.Keywords: magnetic nanoparticle of Fe3O4, immune function, splenocyte proliferation, cytokine
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- 2010
18. Synthesis and Surface Plasmonic Resonance of Stannum Nanocaps
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Yang Xing-Wang, Man Shi-Qing, Xiao Gui-Na, and Lei Xin-Xian
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Surface plasmonic resonance ,Materials science ,business.industry ,Optoelectronics ,Physical and Theoretical Chemistry ,business - Published
- 2009
19. Hepatitis B virus‐associated nephropathy in a patient with diabetes mellitus
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Gui-Na Wei, Jia-Xi Chen, Peng-Fei Shan, Qing-Ling Zou, and Qin Ye
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medicine.medical_specialty ,Endocrinology, Diabetes and Metabolism ,Case Report ,Diabetic nephropathy ,medicine.disease_cause ,urologic and male genital diseases ,Gastroenterology ,Nephropathy ,chemistry.chemical_compound ,Diabetes mellitus ,Polyuria ,Internal medicine ,Internal Medicine ,medicine ,Hepatitis B virus‐associated nephropathy ,Hepatitis B virus ,Proteinuria ,business.industry ,General Medicine ,Articles ,medicine.disease ,Clinical Science and Care ,chemistry ,Immunology ,Albuminuria ,Glycated hemoglobin ,medicine.symptom ,business - Abstract
Hepatitis B virus (HBV)‐associated nephropathy is not a rare manifestation of HBV infection; this could result in diagnostic confusion and the possible misidentification of a diabetic patient with albuminuria. We present the first published case of a HBV‐associated nephropathy occurring in a patient with diabetes. The patient was a 24‐year‐old man who was admitted to hospital with 4 days of generalized swelling and oliguria. He had a 3‐year history of weight loss, and a 1‐year history of polydipsia and polyuria before the symptoms of generalized swelling and oliguria appeared. Laboratory tests showed a fasting blood sugar of 15.1 mmol/L and glycated hemoglobin of 18.1%. The 24‐h urine protein excretion was 2807.8 mg and serum albumin was 19.1 g/L. The diagnosis of HBV‐associated nephropathy was confirmed by serological evaluations of HBV antigen and antibodies, immunohistochemical evidence of HBV‐related antigens, and immune complexes in renal biopsies. The decreased proteinuria was observed after antiviral therapy.
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- 2013
20. Calculation of the Phase Equilibria in Nb-Ni-Ti Ternary System
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Zhang Jieyu, Li Chonghe, Wu Guangxin, Zhu Ming, Lu Xionggang, Tan Guangxiang, and Gui Na
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Materials science ,Ternary numeral system ,Phase (matter) ,Thermodynamics ,CALPHAD ,Phase diagram - Published
- 2013
21. Factor analysis–spectrophotometry for the simultaneous determination of valence states of metals
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Gui-na Tang, Bao-ning Wang, and Ka-lin Huang
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Ethanol ,Valence (chemistry) ,medicine.diagnostic_test ,Sodium ,Color reaction ,Analytical chemistry ,chemistry.chemical_element ,Biochemistry ,Analytical Chemistry ,chemistry.chemical_compound ,Chromium ,chemistry ,Spectrophotometry ,Reagent ,Electrochemistry ,medicine ,Environmental Chemistry ,Sulfate ,Spectroscopy - Abstract
Two Mn+–2-(5-bromo-2-pyridylazo)-5-diethylaminophenol systems for the simultaneous determination of the valence states of Cr and Fe using factor analysis were studied. (1) At pH 4.0, CrIII and CrVI react with the reagent to form stable complexes and a slight difference in the wavelengths of maximum absorption (λmax.) between the two complexes is observed when the sodium lauryl sulfate, which also acts as a solubilizing and sensitizing agent, is added, viz., 590 nm for CrIII and 593 nm for CrVI complexes. (2) In the presence of ethanol, both FeII and FeIII form 1:2 complexes with the reagent at pH 2.5–3.5 and the λmax. of the FeII and FeIII complexes is at 557 and 592 nm, respectively. In the target transformation factor analysis, the K coefficients calculated from the standard mixtures by classical least-squares analysis and a non-zero intercept added to each wavelength are used as the target vector instead of the pure component standards; this can decrease the analysis errors introduced by the interaction between the two species and by deviations from Beer's law.
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- 1993
22. [Influence of magnetic Fe3O4 nanoparticle on functions of lymphocytes and macrophages in mice]
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Nan, Jin, Jun, Wang, Bao-An, Chen, Jia-Hua, Ding, Chong, Gao, Jian, Cheng, Gang, Zhao, Wen, Bao, Feng, Gao, Guo-Hua, Xia, Yin, Zhou, Yue, Chen, Gui-Na, Zhou, Xiao-Mao, Li, and Xue-Mei, Wang
- Subjects
Immunity, Cellular ,Mice ,Mice, Inbred ICR ,Phagocytosis ,Macrophages ,Animals ,Lymphocytes ,Magnetite Nanoparticles - Abstract
This study was purposed to investigate the effects of magnetic nanoparticle of Fe3O4 (Fe3O4-MNPs) on murine immune system. ICR mice were assigned randomly into four groups which were treated with normal saline, low, middle and high dose of MNP-Fe3O4 respectively. The mice were killed after being exposed by intragastric administration for 2 weeks. The ratios of spleen weight to body weight, lymphocyte transformation rate in spleen suspension and phagocytic index of macrophage in abdominal cavity were detected. The results showed that the ratios of spleen weight to body weight in Fe3O4-MNP groups were not significantly different in comparison with the control (p0.05). The lymphocyte transformation rate in spleen suspension in Fe3O4-MNP groups were all higher than that in control group (-0.1775 +/- 0.0246), especially in the middle dose group (0.1833 +/- 0.0593) (p0.05), and the phagocytic index of macrophages in abdominal cavity of middle dose group (0.2051 +/- 0.0213) was higher than that of control group and other two Fe3O4-MNP group (low dose 0.1538 +/- 0.0100, high dose 0.1511 +/- 0.0184) (p0.05). It is concluded that suitable dose of Fe3O4-MNP can enhance the cellular immune activity and phagocytic function of macrophages of mice.
- Published
- 2010
23. [M-FISH technique in diagnosis and prognostic analysis for acute leukemia with complex chromosomal aberrations]
- Author
-
Gui-Na, Zhou and Bao-An, Chen
- Subjects
Chromosome Aberrations ,Leukemia ,Karyotyping ,Acute Disease ,Humans ,Chromosome Disorders ,Prognosis ,In Situ Hybridization, Fluorescence - Abstract
The M-FISH includes multi-colour FISH and multiplex FISH, it represents one of the most significant developments in molecular cytogenetics of the past decade. This technique was originally designed to generate 24 colour karyotyping in human's 23 pair chromosome, now the technique has many variations and has been used in different fields. In leukaemia cytogenetics, the M-FISH now is used in detection for AL patients with following chromosome abnormality: (1) harbouring minimal chromosome translocation is respected; (2) chromosome translocation with complex abnormal karyotypes exists in patients with leukemia which are difficulty detected by using conventional method. The final results detected by M-FISH have guide significance for diagnosis, therapy and prognosis of AL patients. In this article the technical basis with commonly used probe for M-FISH, application of M-FISH in diagnosis, evaluation of therapeutic efficacy and prognostic analysis of AL patients are summarised.
- Published
- 2010
24. [Protective effect of calcium dobesilate against early diabetic nephropathy of rat kidney]
- Author
-
Mei-Juan, Gao, Ming, Liu, Bo, Li, Ming-Long, Li, Li-Xiang, Bian, and Gui-Na, Yu
- Subjects
Blood Glucose ,Glycated Hemoglobin ,Male ,Kidney Cortex ,Endothelins ,Calcium Dobesilate ,Hemostatics ,Diabetes Mellitus, Experimental ,Rats ,Random Allocation ,Matrix Metalloproteinase 9 ,Plasminogen Activator Inhibitor 1 ,Albuminuria ,Animals ,Diabetic Nephropathies ,Rats, Wistar - Abstract
The aim of this study is to study the effect of calcium dobesilate on streptozotocin (STZ)-induced early diabetic nephrophathy (DN) in rats. All male Wistar rats were randomly divided into six groups: normal group; DN blank group; calcium dobesilate 75, 150, and 300 mg x kg(-1) groups and perindopril 0.4 mg x kg(-1) group. Blood glucose and the 24 h urinary albumin were measured dynamically during the experiment, after 8 weeks administration, the level of glycosylated hemoglobin (HbA1c) was determined, the expressions of plasminogen activator inhibitor-1 (PAI-1) and matrix metalloprotein-9 (MMP-9) in cortex of kidney were examined with immunohistochemical staining. The endothelin (ET) in plasma and kidney cortex was measured with radioimmunoassay, renal pathomorphism was observed with light and electron microscopes. Calcium dobesilate could decrease the 24 h urinary albumin and ET in plasma and kidney cortex, down-regulate the expression of PAI-1, and up-regulate MMP-9 in kidney. These findings suggested that calcium dobesilate could protect blood vessel endothelium, inhibit kidney fibrous degeneration, ameliorate renal pathological damage, and protect kidney function in many ways.
- Published
- 2009
25. Motion of spiral waves induced by local pacing
- Author
-
Gui-Na Wei, Bing-Wei Li, Jiang-Xing Chen, and Jiang-Rong Xu
- Subjects
Physics ,local pacing ,Deformation (mechanics) ,QC1-999 ,Quantitative Biology::Tissues and Organs ,Phase (waves) ,General Physics and Astronomy ,Motion (geometry) ,Mechanics ,Rotation ,spiral wave ,Classical mechanics ,82.40.ck ,87.19.hh ,Spiral wave ,47.54.fj ,resonant drift ,Spiral (railway) ,weak deformation approximation ,Astrophysics::Galaxy Astrophysics - Abstract
The motion of spiral waves in excitable media driven by a weak pacing around the spiral tip is investigated numerically as well as theoretically. We presented a Bifurcations diagram containing four types of the spiral motion induced by different frequencies of pacing: rigidly rotating, inward-petal meandering, resonant drift, and outward-petal meandering spiral. Simulation shows that the spiral resonantly drifts when the frequency of pacing is close to that of the spiral rotation. We also find that the speed and direction of the drift can be efficiently controlled by means of the strength and phase of the local pacing, which is consistent with analytical results based on the framework of the weak deformation approximation.
- Published
- 2008
26. Kinetic Behavior of Ligand-Displacement Reaction of Iron(II) and Iron(III)-EGTA Complexes with 2-(5-Bromo-2-pyridylazo)-5-diethylaminophenol by Flow Injection Analysis and Its Application
- Author
-
Gui-Na Tang, Le-Yong Deng, and Bao-Ning Wang
- Subjects
Flow injection analysis ,chemistry.chemical_classification ,chemistry.chemical_compound ,EGTA ,Azo compound ,chemistry ,Ligand ,Diamine ,Carboxylic acid ,Inorganic chemistry ,Kinetics ,Single displacement reaction ,Analytical Chemistry - Published
- 1994
27. CyclophilinA inhibits cholesterol accumulationviathe caveolin-1 bonding-dependent pathway in vascular smooth muscle cells
- Author
-
Bing Yang Zhu, Qin‑hui Tuo, Duan‑fang Liao, Gui‑na Xu, and Yan Guo
- Subjects
chemistry.chemical_compound ,Vascular smooth muscle ,chemistry ,Cholesterol ,Caveolin 1 ,Myocyte ,Cell Biology ,General Medicine ,Mural cell ,Cell biology - Published
- 2010
28. Selection of the functional domains of Daxx and its effect on cholesterol contents in HepG2 cells
- Author
-
Gui‑na Xu, Bing-Yang Zhu, Hong-Yan Ling, Qin‑hui Tuo, Rui Yi, and Duan‑fang Liao
- Subjects
chemistry.chemical_compound ,Death-associated protein 6 ,chemistry ,Cholesterol ,Hepg2 cells ,Cell Biology ,General Medicine ,Biology ,Selection (genetic algorithm) ,Cell biology - Published
- 2010
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