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In this paper the authors propose an immune network which considers B cell interactions based on the immune response network of an organism. The authors modeled a network based on an immune mechanism which uses B cell interactions for an immune response network with interactions between B cells and T cells in an organism. They then created an immune network. Finally, the authors describe the validity of pattern recognition using their immune network by performing simulations on the proposed network. © 2001 Scripta Technica, Syst Comp Jpn, 32(10): 31–41, 2001 [ABSTRACT FROM AUTHOR]

The molecular mechanisms whereby PPARγ inhibits inflammatory gene expression in macrophages are poorly understood. In a recent Nature paper, provide a new model for trans-repression in which ligand-dependent SUMOylation of PPARγ results in its recruitment to the promoters of inflammatory genes where it inhibits transcription by preventing clearance of corepressor complexes. [Copyright &y& Elsevier]