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Non-alcoholic fatty liver disease (NAFLD) in non-obese individuals is a global epidemic. NAFLD is related with type II diabetes mellitus(T2DM); thus may have a common immunological connection towards its genesis. We aimed to delineate the role of soluble-Toll-like receptor 2(sTLR2) mediated immunomodulation in the pathogenesis of NAFLD without or with T2DM.

Transfusion-associated graft-vs-host disease (TAGVHD) is a rare complication of blood transfusion. Unlike GVHD associated with hematopoietic stem cell transplantation TA-GVHD involves the patient's bone marrow and leads to bone marrow aplasia. We report a case of TA-GVHD in a 45-year-old post-hysterectomy patient after packed red blood cell transfusion from a sibling donor. The patient had fever, maculopapular rashes all over the body, elevated transaminases, and hyperglycemia after a week of the blood transfusion. Severe pancytopenia and bone marrow aplasia followed and she succumbed to her disease after 3 weeks of onset.