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• Person-centered dementia is socially and culturally relevant in developing countries with limited long-term care resource. • Facilitating person-centered communication should be a key domain when educators are designing training sessions for care aides. • Healthcare professionals need additional training to gain the skills needed to find formal and informal ways to interact more frequently with frontline staff. • Care aides' mental models need to be altered by the sensemaking of person-centered care. • Care aides need to be encouraged to take more adaptive and active roles in leading case presentation and discussions. Semi-skilled or unskilled nursing care aides primarily provide direct care to residents in long-term care (LTC) facilities in China and many other countries around the world. There has been a significantly increased commitment from nurses and other formally trained professionals to provide person-centered care (PCC) for people with dementia (PwD). However, it is still unclear how nursing care aides who provide direct care to older residents with dementia understand and adopt PCC in their daily work. It is of utmost importance to understand person-centered dementia care from the perspectives of care aides, and to identify implications to facilitate and sustain their efforts in providing quality care for older residents with dementia. We found that the seemingly beneficial mental models used by care aides in their work can hinder them from playing a more adaptive role in tailoring their care to the needs of older residents. Infantilizing older residents with dementia and labeling them using mother wit can prevent meaningful, equal, and person-centered conversations between both parties. Care aides do not have regular formal interactions and sensemaking with nurses and other professionals in nursing homes. Increasing interactions and communication between care aides and health care professionals in nursing homes can lead to insight for changing the approach to in-service training to achieve better acceptance by care aides. The current study derives implications for operationalizing and embedding the principles of PCC in daily care. [ABSTRACT FROM AUTHOR]

Although several lines of evidence existed suggesting that Mortalin was linked with survival in malignant tumors; it has been barely described regarding the prognostic involvement of its expression in hepatocellular carcinoma (HCC). Herein, to understand the prognostic meaning of Mortalin expression, Immunohistochemistry was undertaken to observe the immunohistochemical characteristics of Mortalin on HCC tissue microarray consisting of 90 cases of HCC and its paired normal control dots, followed by detailed statistical analysis with the accompanying clinicopathological variables available, including gender, age, tumor size, differentiation, cirrhosis, vascular invasion, clinical stage, T classification and intrahepatic metastases. Meanwhile, Kaplan-Meier survival curve was plotted to analyze the prognostic difference for patients with high and low expression of Mortalin. It was exhibited that Mortalin was over-expressed in HCC tissues relative to paired normal control and elevated Mortalin significantly correlated with vascular invasion, clinical stage and intrahepatic metastasis. Kaplan-Meier survival analysis revealed that Mortalin was remarkably associated with overall survival and disease-free survival. Multivariate Cox regression analysis showed that expression of Mortalin was an independent prognostic factor in HCC. Collectively, the data we provided here support the prognostic prediction value of Mortalin in HCC. • Mortalin was over-expressed in HCC tissues. • Over-expressed Mortalin significantly correlated with vascular invasion, clinical stage, and intrahepatic metastasis. • Over-expressed Mortalin was associated with poor prognosis in HCC. [ABSTRACT FROM AUTHOR]

• A metasurface consisting of disk-ring Si nanostructures on a SiO2 substrate is proposed and numerically simulated. • The Si disk-ring structure can excite and manipulate anapole state. • A transmission dip with a bandwidth of 0.34 nm and a Q-factor of 4460 is shown with maximum E-field enhancement of 346 times. • When the central disk is eccentric, the maximum E-field enhancement can be up to 468 times. • A sensing performance of 387 nm/RIU is shown. In this work, a metasurface consisting of disk-ring Si nanostructures on a SiO 2 substrate is proposed and numerically simulated. The Si disk-ring structure can excite and manipulate anapole state, and periodic array supports lattice resonance simultaneously, which can improve the near-field enhancement in the gap region. The maximum E-field enhancement can be up to 346 times, and a transmission dip with an ultra-narrow bandwidth of 0.34 nm and a Q -factor of 4460 is shown. When the central disk has an offset, the near-field enhancement can be affected. In the case of y -direction offset, the maximum E-field enhancement can be up to 468 times. The near field energy is concentrated in the gap region, easy to interact with probing molecule in surrounding environment. Meanwhile, the designed metasurface shows a sensing performance of 387 nm/RIU. The strong energy confinement and high Q -factor of the proposed structure give an opportunity to enhance the interaction between light and matter, which may have potential applications in nonlinear optics, optical sensors and surface enhanced Raman scattering. [ABSTRACT FROM AUTHOR]

• An all-dielectric silicon nanostructure based on anapole mode is proposed, and its numerical study and analysis are carried out. • By manipulating the anapole mode and using the mirror reflection effect of metal, the electromagnetic field of the structure is enhanced to 125 times, which can be compared with the metal plasmon structure. • When the metal is used as the substrate, an ultranarrow perfect absorption with a linewidth of only 1.38 nm is obtained at the resonant wavelength, and the corresponding Q factor is as high as 602. Its performance is better than many published structures. Compared with the plasmon resonance suppressed by ohmic loss, high refractive index dielectric metamaterials have become a new frontier of nanophotonics because of their small loss. In this work, we numerically simulate the structures of Si and slotted Si nanodisk with the SiO 2 substrate, and slotted Si nanodisk with the Ag substrate. The slotted Si nanodisk excited with anapole mode reveals strong near field enhancement about 70 times in slotted gap regions. When the slotted Si nanodisk deposited on Ag substrate separated by SiO 2 layer, the designed structure shows the ultranarrow perfect absorption with the line width of 1.38 nm and the quality factor of 602, and the corresponding electric field enhancement in the Si nanodisk increases to 125. Our work provides a new idea for electric field enhancement and ultranarrow perfect absorption based on manipulation of anapole mode in dielectric metamaterials, and provides potential applications in optical sensors, nonlinear optics and surface enhanced Raman scattering. [ABSTRACT FROM AUTHOR]

• This paper is investigated a silicon-dielectric-metal nanostructure, it supports the optional anapole mode due to the destructive interference between electric and toroidal dipoles. • Such the proposed nanostructure exhibits a near-perfect ultra-narrow absorption spectrum in the near infrared region with the absorption bandwidth of 0.48 nm and a high-quality factor up to 1763. In addition, the structure we designed has both excellent sensing performance and field enhancement performance, which can be used to design multi-function chips. • Our design is a simple flat structure, which is easy to process and manufacture in actual production. This paper is investigated a silicon-dielectric-metal nanostructure, it supports the optional anapole mode due to the destructive interference between electric and toroidal dipoles. Such the proposed nanostructure exhibits a near-perfect ultra-narrow absorption spectrum in the near infrared region with the absorption bandwidth (FWHM) of 0.48 nm and a high-quality (Q) factor up to 1763. Besides inherently low dissipative losses and strong anapole response, this optical nanostructure can demonstrate subtle refractive index sensing properties. Our work shed new light on active ultra-narrow band perfect absorption based on the optical anapole mode, and provides potential applications such as optical sensors, narrow-band filter, non-radiative data transmission and biomolecules manipulation. [ABSTRACT FROM AUTHOR]

Resonant plasmonic nanostructures have attracted much attention due to their exotic optical properties. In this work, we numerically investigate single- and dual-gap ring structures, respectively, and they can be used for refractive index sensing by exciting the gap plasmon mode with sharp resonance spectra. The dual-gap ring plasmonic sensor shows the dual-channel properties and the corresponding sensitivities are 513 nm/RIU and 809 nm/RIU with the refractive indices range of 1.32–1.37, respectively. Furthermore, the gap ring structures are highly symmetrical, and have advantages in fabrication and pave the way for advanced optical devices to detect bio-molecules. [ABSTRACT FROM AUTHOR]

• The graphene based metal–insulator-metal (MIM) metamaterial is investigated to realize an active and adjustable multi-band perfect absorber. • As the symmetry of T-shaped cavities is broken, the previous dual-band absorption will be converted to tri-band absorber. • The sensitivity is elaborately examined with different concentrations of CS 2 dropped into the cavities, and the refraction index per unit can reach up to a high value of 1673.33 nm/RIU. The graphene based metal-insulator-metal (MIM) metamaterial is numerically investigated to realize an active and adjustable multi-band perfect absorber, which is composed of an asymmetric double T-shaped cavity on the top layer. As the symmetry of T-shaped cavities is broken, the previous dual-band absorption will be converted to tri-band absorber. The corresponding electric field distribution at each resonant position is invesitgated to figure out the physical mechanism. More interestingly, these resonant peaks will split into multiband with further destruction of the central symmetry. In addition, non-contact dynamic control of perfect absorption is explored by tuning the Fermi energy, the polarization angle and the incident angle. Finally, the sensitivity of our proposed design is elaborately examined with different concentrations of CS 2 dropped into the cavities. The results demonstrate that the refraction index per unit can reach up to a high value of 1673.33 nm/RIU. Therefore, this work delivers a new strategy to design tunable multi-band absorbers and has potential applications in highly tunable optical switchers, sensors and filters. [ABSTRACT FROM AUTHOR]

• Preparation of TiO 2 nanotube arrays by anodic oxidation. • The optimum parameters of the water content in electrolyte, anodizing time and ultrasonic post-treatment were determined. • The effects of each parameter on the morphology and crystal form of TiO 2 nanotube arrays was studied. • The effects of TiO 2 nanotube arrays with different anodization parameter on the photoelectric performance of DSSC were obtained. In this paper, TiO 2 nanotube arrays were prepared by anodic oxidation method. The effects of water content, anodizing time and sample post-treatment on the morphology and crystal structure of TiO 2 nanotube arrays were systematically investigated. We explored the performance of dye-sensitized solar cells (DSSCs) based on dye N-719. The TiO 2 nanotube arrays prepared under different water content and different anodizing time conditions were used as photoanodes. The results show that DSSC has best photovoltaic performance when the water content is 2 vol%. With the increase of oxidation time, J sc increases continuously, open voltage (V oc) and fill factor (FF) increase first and then decrease. The best optoelectronic properties obtained that the short circuit current, open circuit voltage, fill factor and photoelectric conversion efficiency as following, J sc = 5.2 mA/cm2, V oc = 0.7 V, FF = 0.54, η = 1.96% respectively. [ABSTRACT FROM AUTHOR]

• Cultured Cordyceps sinensis polysaccharides (CSP) improved intestinal morphology. • CSP restored intestinal related enzymes, growth factor and its receptor. • CSP upregulated tight junction proteins expression and downregulated MLCK, p-MLC. • CSP recovered tight junctions via MAPKs pathways. • CSP could attenuate cyclophosphamide-induced intestinal barrier injury in mice. Intestine is not only the largest digestive and absorbing organ, but also an important defensive barrier of the body. Maintaining healthy intestinal barrier is a prerequisite for intestinal function. In this study, polysaccharides from the cultured Cordyceps sinensis (CSP) were orally given to cyclophosphamide (Cy)-treated mice to investigate its protective effect on intestinal barrier injury. Results showed that CSP had positive effects on intestinal morphology, including restoring villus length and crypt depth as well as improving quantity of goblet cells and mucins expression. Furthermore, CSP enhanced intestinal alkaline phosphatase (IAP), diamine oxidase (DAO), epidermal growth factor (EGF) and its receptor (EGFR). In addition, occludin, claudin-1 and zonula occludins (ZO)-1 were upregulated and myosin light chain kinase (MLCK), p-MLC were downregulated by CSP. Moreover, CSP promoted p-ERK and inhibited p-JNK, p-p38. These findings suggested that CSP could attenuate Cy-induced intestinal barrier injury which maybe associated with mitogen-activated protein kinases (MAPKs) pathways. [ABSTRACT FROM AUTHOR]

We theoretical design of a triple-band perfect metamaterial absorber in the THz frequency range. We find the split ring resonator structure has three absorption peaks at frequencies 3.56 THz, 10.38 THz and 12.96 THz with absorption efficiency 99.57%, 99.98% and 99.76%, respectively. • By FDTD simulation calculation, we initially found that the presented split ring resonator has three perfect absorption peaks. • The absorption performance of the split ring resonator structure can be flexibly tuned by changing the chemical potential or relaxation time. • The proposed triple-band perfect metamaterial absorber has better sensing performance in high frequency bands. A triple-band perfect metamaterial absorber based on periodically arranged graphene split ring resonator (SRR) is proposed in this study. The calculation results by the FDTD method indicate that the SRR structure has three absorption peaks at frequencies 3.56 THz, 10.38 THz and 12.96 THz with absorption efficiency 99.57%, 99.98%, and 99.76%, respectively. By changing the chemical potential or relaxation time, the absorption characteristics of the split ring resonator structure can be flexibly tuned. Furthermore, we also examine the sensing performance of the proposed metamaterial absorber, the sensing performance of the high-frequency band is significantly higher than the low-frequency band. We believe that our results will pave the ways for the development of applications using metamaterials with high efficiency and multi-band spectral selectivity in biochemical sensing, optical switching, and modulating. [ABSTRACT FROM AUTHOR]

The Chinese new intellectuals group came to the stage during the revolutionary of 1911 with some new features, such as with new knowledge structure, values and political ambitions who became truly modem intellectuals. Facing with an increasingly serious national crisis, they were an active part in the great revolutionary practice for the national salvation and "the regeneration of China. " From the spread of revolutionary ideas to the formation of revolutionary groups and development program of the Democratic Revolution, from the ideological struggles with the reformers to the many armed uprisings launched, the new intellectuals had played a pioneering role as a bridge to demonstrate a strong sense of crisis and social responsibility. [ABSTRACT FROM AUTHOR]