1. The role of vitamin D in the immunopathogenesis of allergic skin diseases.
- Author
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Benson, A. A., Toh, J. A., Vernon, N., and Jariwala, S. P.
- Subjects
VITAMIN D ,ALLERGIES ,SKIN diseases ,SKIN inflammation ,ATOPIC dermatitis ,CELLULAR immunity ,FOOD allergy - Abstract
To cite this article: Benson AA, Toh JA, Vernon N, Jariwala SP. The role of vitamin D in the immunopathogenesis of allergic skin diseases. Allergy 2012; 67: 296-301. Abstract Vitamin D plays key roles in innate and adaptive immunity through the stimulation of Toll-like receptors, increasing pro-inflammatory cytokine production, and possibly enhancing T helper type 2 responses. These mechanisms may explain the growing body of evidence connecting vitamin D to allergic diseases, including asthma, food allergies, and allergic rhinitis. The data relating vitamin D to allergic skin diseases are equivocal with studies linking both high and low vitamin D levels to an increased risk of developing atopic dermatitis. In this paper, we describe the role of vitamin D in the immunopathogenesis of atopic dermatitis and other allergic skin diseases. [ABSTRACT FROM AUTHOR]
- Published
- 2012
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