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Your search keyword '"Daugulis, Olafs"' showing total 11 results
Start Over Author "Daugulis, Olafs" Journal angewandte chemie international edition
11 results on '"Daugulis, Olafs"'

5. Palladium-Catalyzed Pyrazole-Directed sp3 C−H Bond Arylation for the Synthesis of β-Phenethylamines.

Author

Gulia, Nurbey and Daugulis, Olafs

Subjects
*PYRAZOLES, *ARYLATION, *ARYL iodides, *HALIDES, *OZONOLYSIS
Abstract

We have developed a method for palladium-catalyzed, pyrazole-directed sp3 C−H bond arylation by aryl iodides. The reaction employs a Pd(OAc)2 catalyst at 5-10 mol % loading and silver(I) oxide as a halide-removal agent, and it proceeds in acetic acid or acetic acid/hexafluoroisopropanol solvent. Ozonolysis of the pyrazole moiety affords pharmaceutically important β-phenethylamines. [ABSTRACT FROM AUTHOR]

Published
2017
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10. Cobalt-Catalyzed, Aminoquinoline-Directed C(sp2)H Bond Alkenylation by Alkynes.

Author

Grigorjeva, Liene and Daugulis, Olafs

Subjects
*COBALT, *CATALYSIS, *QUINOLINE, *CHEMICAL bonds, *ALKENYLATION, *ALKYNES
Abstract

A method for cobalt-catalyzed, aminoquinoline- and picolinamide-directed C(sp2)H bond alkenylation by alkynes was developed. The method shows excellent functional-group tolerance and both internal and terminal alkynes are competent substrates for the coupling. The reaction employs a Co(OAc)2⋅4 H2O catalyst, Mn(OAc)2 co-catalyst, and oxygen (from air) as a terminal oxidant. [ABSTRACT FROM AUTHOR]

Published
2014
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