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Your search keyword '"Tse, Eric"' showing total 25 results
Start Over Author "Tse, Eric" Journal annals of hematology
25 results on '"Tse, Eric"'

19. PD1 blockade with low-dose nivolumab in NK/T cell lymphoma failing L-asparaginase: efficacy and safety.

Author

Chan, Thomas S. Y., Li, Jamilla, Loong, Florence, Khong, Pek-Lan, Tse, Eric, and Kwong, Yok-Lam

Subjects
KILLER cells, HODGKIN'S disease, APOPTOSIS, IMMUNOGLOBULINS
Abstract

The article presents case studies of 59-year-old man, 43-year-old man, and 80-year-old woman who were diagnosed with extra nodal natural killer (NK)/T cell lymphoma. Topics discussed include information on Anti-programmed cell death protein 1 (PD1) antibodies which are off-label non-reimbursed drugs for NK/T cell lymphomas; use of nivolumab in Hodgkin lymphoma; and determination of PD1 blockade as an important strategy in NK/T cell lymphomas.

Published
2018
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21. Breakthrough invasive fungal diseases during echinocandin treatment in high-risk hospitalized hematologic patients

Author

Chan, Thomas S. Y., primary, Gill, Harinder, additional, Hwang, Yu-Yan, additional, Sim, Joycelyn, additional, Tse, Alan C. T., additional, Loong, Florence, additional, Khong, Pek-Lan, additional, Tse, Eric, additional, Leung, Anskar Y. H., additional, Chim, Chor-Sang, additional, Lie, Albert K. W., additional, and Kwong, Yok-Lam, additional

Published
2013
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25. T-cell large granular lymphocyte leukemia: an Asian perspective.

Author

Yok-Lam Kwong, Wing-Yan Au, Leung, Anskar Y. H., Tse, Eric W. C., Kwong, Yok-Lam, and Au, Wing-Yan

Subjects
LEUKEMIA, RHEUMATOID arthritis, JOINT diseases, AUTOIMMUNE diseases, ERYTHROCYTE disorders
Abstract

To characterize T-cell large granular leukemia in Asia, 22 Chinese patients from a single institute were reported, together with an analysis of 88 Asian and 272 Western patients identified from the literature. In our cohort, anemia due to pure red cell aplasia (PRCA) occurred in 15/22 (68%) of cases, being the most common indication for treatment. Neutropenia was only found in 8/22 (36%) cases, and recurrent infections, the most important clinical problem in Western patients, were not observed. None of our cases presented with rheumatoid arthritis. These clinical features were consistently observed when compared with the 88 other Asian patients. Combined data from our cohort and other Asian cases showed that Asian patients, compared with Western patients, had more frequent anemia (66/110, 60% versus 113/240, 47%; p=0.044), attributable to a much higher incidence of PRCA (52/110, 47% versus 6/143, 4%; p<0.001). However, Western patients presented more frequently than Asian patients with neutropenia (146/235, 62% versus 33/110, 30%; p<0.001) and splenomegaly (99/246, 40% versus 16/110, 15%; p< 0.001). Notably, Western patients were about eight to ten times more likely than Asian patients to have rheumatoid arthritis (73/272, 27% versus 4/106, 4%; p<0.001) and recurrent infections (81/272, 30% versus 3/107, 3%; p<0.001). These clinicopathologic differences have important implications on disease pathogenesis and treatment. [ABSTRACT FROM AUTHOR]

Published
2010
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