1. Wilson Disease in Children; Chelation Therapy or Liver Transplantation? A 10-Year Experience from Pakistan
- Author
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Naurin Ali, Sabeen Abid Khan, Sahira Aaraj, Faisal Saud Dar, and Munir Iqbal Malik
- Subjects
Male ,Pediatrics ,medicine.medical_specialty ,Oral treatment ,Adolescent ,medicine.medical_treatment ,Urinary system ,Consanguinity ,Disease ,Liver transplantation ,Hepatolenticular Degeneration ,medicine ,Humans ,Pakistan ,Chelation therapy ,Child ,Retrospective Studies ,Transplantation ,Original Paper ,business.industry ,Incidence (epidemiology) ,Acute-On-Chronic Liver Failure ,Retrospective cohort study ,General Medicine ,Hospitals, Pediatric ,Chelation Therapy ,Liver Transplantation ,((2,3,7,8,12,13,17,18)-octaethylporphinato)copper (II) ,Child, Preschool ,Female ,business - Abstract
BACKGROUND Wilson disease (WD) is a rare genetic disorder with vast clinical presentations and a higher incidence in areas where consanguinity is common. Most patients can be treated with oral chelation, but some require advanced surgical intervention, like liver transplantation (LT). This study aims to review outcomes of WD patients presenting to a tertiary care center over a period of 10 years. MATERIAL AND METHODS This retrospective analysis was conducted at Shifa International Hospital, Islamabad, Pakistan. Patients
- Published
- 2021