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1. Treg Cell Numbers and Function in Patients With Antibiotic-Refractory or Antibiotic-Responsive Lyme Arthritis.

Author

Shiqian Shen, Shin, Junghee J., Strle, Klemen, McHugh, Gail, Xin Li, Glickstein, Lisa J., Drouin, Elise E., and Steere, Allen C.

Subjects
*CYTOLOGICAL research, *LYME disease, *SYNOVIAL fluid, *TREATMENT of arthritis, *LABORATORY mice
Abstract

The article presents a study which examined the function and number of Treg cells in patients with antibiotic-refractory Lyme arthritis. According to the authors, Treg cells were functional in patients with antibiotic-refractory arthritis while in some patients, higher number of Treg cells in synovial fluid appeared to be involved in the treatment of arthritis. In a mouse model, the authors explain that antibiotic-refractory arthritis and lower number of Treg cells were unable to achieve the treatment of synovial disease.

Published
2010
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