1. Functional mapping of the motor cortex of the rat using transdural electrical stimulation.
- Author
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Fonoff ET, Pereira JF Jr, Camargo LV, Dale CS, Pagano RL, Ballester G, and Teixeira MJ
- Subjects
- Animals, Evoked Potentials, Motor, Male, Motor Activity physiology, Rats, Rats, Wistar, Brain Mapping methods, Electric Stimulation methods, Motor Cortex physiology
- Abstract
Motor cortex stimulation oriented by functional cortical mapping is used mainly for treating otherwise intractable neurological disorders, however, its mechanism of action remains elusive. Herein, we present a new method for functional mapping of the rat motor cortex using non-invasive transdural electrical stimulation. This method allows a non-invasive mapping of the surface of the neocortex providing a differentiation of representative motor areas. This study may facilitate further investigation about the mechanisms mediating the effects of electrical stimulation, possibly benefiting patients who do not respond to this neuromodulation therapy.
- Published
- 2009
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