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Your search keyword '"Wu, Fusheng"' showing total 2 results
Start Over Author "Wu, Fusheng" Journal biochemical & biophysical research communications
2 results on '"Wu, Fusheng"'

1. Role of specific microRNAs for endothelial function and angiogenesis

Author

Wu, Fusheng, Yang, Zeran, and Li, Guohong

Subjects
*NON-coding RNA, *ENDOTHELIUM, *NEOVASCULARIZATION, *CELL proliferation, *CELL migration, *MORPHOGENESIS -- Molecular aspects, *TARGETED drug delivery, *CANCER treatment
Abstract

Abstract: Accumulating evidence indicates that various aspects of angiogenesis, such as proliferation, migration, and morphogenesis of endothelial cells, can be regulated by specific miRNAs in an endothelial-specific manner. As novel molecular targets, miRNAs have a potential value for treatment of angiogenesis-associated diseases such as cancers, inflammation, and vascular diseases. In this article, we review the latest advances in the identification and validation of angiogenesis-regulatory miRNAs and their targets, and discuss their roles and mechanisms in regulating endothelial cell function and angiogenesis. [Copyright &y& Elsevier]

Published
2009
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2. MiR-29a modulates the angiogenic properties of human endothelial cells.

Author

Yang, Zeran, Wu, Lingjiao, Zhu, Xiuming, Xu, Jie, Jin, Rong, Li, Guohong, and Wu, Fusheng

Subjects
*MICRORNA, *VASCULAR endothelial growth factors, *HYPOXEMIA, *CELL cycle regulation, *CELL proliferation, *NEOVASCULARIZATION
Abstract

Highlights: [•] miR-29a may be stimulated by hypoxia in HUVEC. [•] miR-29a regulates cell cycle, proliferation and tube network formation of HUVEC. [•] HMG box-containing protein-1(HBP1) is a direct target of miR-29a. [•] miR-29a has a potential value for treating angiogenesis-associated diseases. [ABSTRACT FROM AUTHOR]

Published
2013
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