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Start Over Author "Chen, Li-Feng" Journal bioorganic & medicinal chemistry letters

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1. New labdane diterpenoids from Croton laui and their anti-inflammatory activities.

Author

Yang, Li, Zhang, Yu-Bo, Chen, Li-Feng, Chen, Neng-Hua, Wu, Zhong-Nan, Jiang, Si-Qi, Jiang, Lin, Li, Guo-Qiang, Li, Yao-Lan, and Wang, Guo-Cai

Subjects
*DITERPENES, *ANTI-inflammatory agents, *LABDANES, *CROTON (Genus), *X-ray diffraction, *THERAPEUTICS
Abstract

Nine new labdane diterpenoids ( 1 – 9 ) were isolated from the aerial parts of Croton laui , along with eight known analogues ( 10 – 17 ). Their structures were identified on the basis of the spectral data (IR, UV, HRESIMS, 1D and 2D NMR), and the structure of 8 was confirmed by single crystal X-ray diffraction analyses. In addition, compounds 1 , 4 , 7 , 8 , and 14 showed weak anti-inflammatory activities in LPS-stimulated RAW 264.7 cells. [ABSTRACT FROM AUTHOR]

Published
2016
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