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Start Over Author "Tofazzal Hossain, Md." Journal bioscience, biotechnology, and biochemistry
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1. Structural insight into the active site of a Bombyx moriunclassified glutathione transferase

Author

Tofazzal Hossain, MD. and Yamamoto, Kohji

Abstract

Glutathione transferases (GSTs) are major detoxification enzymes that play central roles in the defense against various environmental toxicants as well as oxidative stress. Here, we identify amino acid residues of an unclassified GST from Bombyx mori, bmGSTu-interacting glutathione (GSH). Site-directed mutagenesis of bmGSTu mutants indicated that amino acid residues Asp103, Ser162, and Ser166 contribute to catalytic activity.

Published
2015
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