1. Production and Characterization of Durvillaea antarctica Enzyme Extract for Antioxidant and Anti-Metabolic Syndrome Effects.
- Author
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Shih, Ming-Kuei, Hou, Chih-Yao, Dong, Cheng-Di, Patel, Anil Kumar, Tsai, Yung-Hsiang, Lin, Mei-Chun, Xu, Zheng-Ying, Perumal, Pitchurajan Krishna, Kuo, Chia-Hung, and Huang, Chun-Yung
- Subjects
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ANGIOTENSIN I , *CELLULASE , *ENZYMES , *MOLECULAR weights , *POLYSACCHARIDES , *METABOLIC syndrome , *EXTRACTS - Abstract
In this study, three enzyme hydrolysate termed Dur-A, Dur-B, and Dur-C, were produced from Durvillaea antarctica biomass using viscozyme, cellulase, and α-amylase, respectively. Dur-A, Dur-B, and Dur-C, exhibited fucose-containing sulfated polysaccharide from chemical composition determination and characterization by FTIR analyses. In addition, Dur-A, Dur-B, and Dur-C, had high extraction yields and low molecular weights. All extracts determined to have antioxidant activities by DPPH (2,2-diphenyl-1-picrylhydrazyl), ABTS (2,20-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid) diammonium salt), and ferrous ion-chelating methods. All extracts were also able to positively suppress the activities of key enzymes involved in metabolic syndrome: angiotensin I-converting enzyme (ACE), α-amylase, α-glucosidase, and pancreatic lipase. In general, Dur-B exhibited higher antioxidant and higher anti-metabolic syndrome effects as compared to the other two extracts. Based on the above health promoting properties, these extracts (especially Dur-B) can be used as potential natural antioxidants and natural anti-metabolic syndrome agents in a variety of food, cosmetic, and nutraceutical products for health applications. [ABSTRACT FROM AUTHOR]
- Published
- 2022
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