Search

Your search keyword '"Maiuri, Maria Chiara"' showing total 14 results
Start Over Author "Maiuri, Maria Chiara" Journal cell cycle
14 results on '"Maiuri, Maria Chiara"'

1. Metabolic interactions between cysteamine and epigallocatechin gallate

Author

Izzo, Valentina, primary, Pietrocola, Federico, additional, Sica, Valentina, additional, Durand, Sylvère, additional, Lachkar, Sylvie, additional, Enot, David, additional, Bravo-San Pedro, José Manuel, additional, Chery, Alexis, additional, Esposito, Speranza, additional, Raia, Valeria, additional, Maiuri, Luigi, additional, Maiuri, Maria Chiara, additional, and Kroemer, Guido, additional

Published
2017
Full Text
View/download PDF

2. Erratum to Morselli E, et al. Cell Cycle 2008; 7:3056–61

Author

Morselli, Eugenia, primary, Tasdemir, Ezgi, additional, Maiuri, Maria Chiara, additional, Galluzzi, Lorenzo, additional, Kepp, Oliver, additional, Criollo, Alfredo, additional, Vicencio, José Miguel, additional, Soussi, Thierry, additional, and Kroemer, Guido, additional

Published
2014
Full Text
View/download PDF

3. Coffee induces autophagy in vivo

Author

Pietrocola, Federico, primary, Malik, Shoaib Ahmad, additional, Mariño, Guillermo, additional, Vacchelli, Erika, additional, Senovilla, Laura, additional, chaba, kariman, additional, Niso-Santano, Mireia, additional, Maiuri, Maria Chiara, additional, Madeo, Frank, additional, and Kroemer, Guido, additional

Published
2014
Full Text
View/download PDF

6. Autophagy is required for the activation of NFκB

Author

Criollo, Alfredo, primary, Chereau, Fanny, additional, Malik, Shoaib Ahmad, additional, Niso-Santano, Mireia, additional, Mariño, Guillermo, additional, Galluzzi, Lorenzo, additional, Maiuri, Maria Chiara, additional, Baud, Véronique, additional, and Kroemer, Guido, additional

Published
2012
Full Text
View/download PDF

8. p53 inhibits autophagy by interacting with the human ortholog of yeast Atg17, RB1CC1/FIP200

Author

Morselli, Eugenia, primary, Shen, Shensi, additional, Ruckenstuhl, Christoph, additional, Bauer, Maria Anna, additional, Mariño, Guillermo, additional, Galluzzi, Lorenzo, additional, Criollo, Alfredo, additional, Michaud, Mickael, additional, Maiuri, Maria Chiara, additional, Chano, Tokuhiro, additional, Madeo, Frank, additional, and Kroemer, Guido, additional

Published
2011
Full Text
View/download PDF

13. Autophagy is required for the activation of NFκB

Author

Véronique Baud, Fanny Chereau, Lorenzo Galluzzi, Alfredo Criollo, Guido Kroemer, Maria Chiara Maiuri, Shoaib Ahmad Malik, Mireia Niso-Santano, Guillermo Mariño, A., Criollo, F., Chereau, M., Niso Santano, G., Marino, L., Galluzzi, Maiuri, MARIA CHIARA, V., Baud, and G., Kroemer

Subjects
Vesicular Transport Proteins, IκB kinase, Biology, Autophagy-Related Protein 7, Autophagy-Related Protein 5, Mice, Enzyme activator, NF-KappaB Inhibitor alpha, RNA interference, Cell Line, Tumor, Autophagy, Animals, Humans, RNA, Small Interfering, Molecular Biology, Tumor Necrosis Factor-alpha, Kinase, NF-kappa B, Cell Biology, I-kappa B Kinase, Cell biology, Enzyme Activation, IκBα, Cancer research, Beclin-1, I-kappa B Proteins, RNA Interference, Signal transduction, Apoptosis Regulatory Proteins, Microtubule-Associated Proteins, DNA Damage, Signal Transduction, Developmental Biology
Abstract

It is well-established that the activation of the inhibitor of NFκB (IκBα) kinase (IKK) complex is required for autophagy induction by multiple stimuli. Here, we show that in autophagy-competent mouse embryonic fibroblasts (MEFs), distinct autophagic triggers, including starvation, mTOR inhibition with rapamycin and p53 inhibition with cyclic pifithrin α lead to the activation of IKK, followed by the phosphorylation-dependent degradation of IκBα and nuclear translocation of NFκB. Remarkably, the NFκB signaling pathway was blocked in MEFs lacking either the essential autophagy genes Atg5 or Atg7. In addition, we found that tumor necrosis factor α (TNFα)-induced NFκB nuclear translocation is abolished in both Atg5- and Atg7-deficient MEFs. Similarly, the depletion of essential autophagy modulators, including ATG5, ATG7, Beclin 1 and VPS34, by RNA interference inhibited TNFα-driven NFκB activation in two human cancer cell lines. In conclusion, it appears that, at least in some instances, autophagy is required for NFκB activation, highlighting an intimate crosstalk between these two stress response signaling pathways.

Published
2012

14. Cell Cycle-Dependent Induction of Autophagy, Mitophagy and Reticulophagy

Author

Jose Miguel Vicencio, Alfredo Criollo, Ezgi Tasdemir, Ilio Vitale, Olivier Geneste, M. Chiara Maiuri, Nicolas Tajeddine, John A. Hickman, Guido Kroemer, Tasdemir, E, Maiuri, MARIA CHIARA, Tajeddine, N, Vitale, I, Criollo, A, Vicencio, Jm, Hickman, Ja, Geneste, O, and Kroemer, G.

Subjects
Cell Cycle, Reticulophagy, Autophagy, Apoptosis, Cell Differentiation, Cell Biology, Tunicamycin, Vacuole, Cell cycle, Biology, Endoplasmic Reticulum, HCT116 Cells, Mitochondria, Rats, Cell biology, chemistry.chemical_compound, chemistry, Vacuolization, Cytoplasm, Mitophagy, Animals, Humans, Molecular Biology, Developmental Biology
Abstract

When added to cells, a variety of autophagy inducers that operate through distinct mechanisms and target different organelles for autophagic destruction (mitochondria in mitophagy, endoplasmic reticulum in reticulophagy) rarely induce autophagic vacuolization in more than 50% or the cells. Here we show that this heterogeneity may be explained by cell cycle-specific effects. The BH3 mimetic ABT737, lithium, rapamycin, tunicamycin or nutrient depletion stereotypically induce autophagy preferentially in the G(1) and S phases of the cell cycle, as determined by simultaneous monitoring of cell cycle markers and the cytoplasmic aggregation of GFP-LC3 in autophagic vacuoles. These results point to a hitherto neglected crosstalk between autophagic vacuolization and cell cycle regulation.

Published
2007

Catalog

Books, media, physical & digital resources
See catalog results