Search

Your search keyword '"Xue-Ya Gou"' showing total 5 results
Start Over Author "Xue-Ya Gou" Journal chemical communications
5 results on '"Xue-Ya Gou"'

1. Highly regioselective and stereoselective synthesis of C-Aryl glycosides via nickel-catalyzed ortho-C–H glycosylation of 8-aminoquinoline benzamides

Author

Ya-Nan Ding, Wei-Yu Shi, Zhi-Jie Niu, Xue-Ya Gou, Yu-Yong Luan, Zhe Zhang, Xi Chen, Yong-Min Liang, and Nian Zheng

Subjects
chemistry.chemical_classification, 8-Aminoquinoline, Glycosylation, Stereochemistry, Aryl, Metals and Alloys, Glycoside, Regioselectivity, General Chemistry, Catalysis, Surfaces, Coatings and Films, Electronic, Optical and Magnetic Materials, chemistry.chemical_compound, chemistry, Functional group, Materials Chemistry, Ceramics and Composites, Stereoselectivity
Abstract

C-Aryl glycosides are of high value as drug candidates. Here a novel and cost-effective nickel catalyzed ortho-CAr–H glycosylation reaction with high regioselectivity and excellent α-selectivity is described. This method shows great functional group compatibility with various glycosides, showing its synthetic potential. Mechanistic studies indicate that C–H activation could be the rate-determining step.

Published
2021

2. A carboxylate-assisted amination/unactivated C(sp2)–H arylation reaction via a palladium/norbornene cooperative catalysis

Author

Yong-Min Liang, Ya-Nan Ding, Yang An, Bo-Sheng Zhang, Zhe Zhang, Xue-Ya Gou, and Ce Liu

Subjects
Pivalic acid, Chemistry, Metals and Alloys, chemistry.chemical_element, General Chemistry, Medicinal chemistry, Catalysis, Surfaces, Coatings and Films, Electronic, Optical and Magnetic Materials, Reaction rate, chemistry.chemical_compound, Materials Chemistry, Ceramics and Composites, Carboxylate, Catellani reaction, Amination, Norbornene, Palladium
Abstract

This report describes a carboxylate-assisted palladium-catalysed Catellani reaction, which is compatible with ortho-amination and unactivated C(sp2)-H arylation. This method was used to synthesize a series of 1-amino substituted dihydrophenanthridines, phenanthridines and 6H-benzo[c]chromenes. Based on kinetic isotope experiments, the kinetic curve proves that pivalic acid accelerates the reaction rate of unactivated C(sp2)-H activation, and thus this rate can keep up with the five membered aryl-norbornene-palladacycle (ANP) intermediate.

Published
2020

3. Visible-light-induced ligand-free RuCl3 catalyzed C–H phosphorylation in water

Author

Bo-Sheng Zhang, Yang An, Hong-Chao Liu, Yong-Min Liang, Wei-Yu Shi, Xue-Ya Gou, Xin-Gang Wang, and Zhe Zhang

Subjects
Chemical substance, Absorption spectroscopy, Chemistry, Ligand, Metals and Alloys, General Chemistry, Photochemistry, Catalysis, Surfaces, Coatings and Films, Electronic, Optical and Magnetic Materials, Solvent, Materials Chemistry, Ceramics and Composites, Photocatalysis, Phosphorylation, Visible spectrum
Abstract

Visible-light-induced C–H phosphorylation of para-CAr–H and heteroarenes was realized using cost-effective RuCl3 as a catalyst. The reaction conditions are green and environmentally friendly, using water as a solvent at room temperature and without ligands. A broad range of highly functional organophosphorus compounds were obtained via a cross-dehydrogenation-coupling (CDC) reaction. In addition, we also proved that RuCl3 is a photocatalyst via its absorption spectrum and on/off light experiments.

Published
2020

4. DMAP and PivOH-promoted amination/allenization reaction

Author

Yuke Li, Yong-Min Liang, Yang An, Xin-Gang Wang, Xue-Ya Gou, Zhe Zhang, and Bo-Sheng Zhang

Subjects
Metals and Alloys, General Chemistry, Combinatorial chemistry, Catalysis, Surfaces, Coatings and Films, Electronic, Optical and Magnetic Materials, chemistry.chemical_compound, Iodobenzenes, chemistry, Materials Chemistry, Ceramics and Composites, Amination, Norbornene
Abstract

This report described the first DMAP and PivOH-promoted ortho-C-H amination and ipso-allenization reaction of iodobenzenes realized by Pd/norbornene cooperative catalysis. Based on control experiments and DFT calculations, we speculated that the three ligands have different functions and mechanism paths in the reaction.

Published
2020

5. Ruthenium-catalyzed ortho-selective CAr–H amination of heteroaryl arenes with di-tert-butyldiaziridinone

Author

Zhao-Zhao Zhou, Yuke Li, Jia-Hui Zhao, Xin-Gang Wang, Hong-Chao Liu, Yong-Min Liang, Bo-Sheng Zhang, and Xue-Ya Gou

Subjects
010405 organic chemistry, Metals and Alloys, chemistry.chemical_element, General Chemistry, Di-tert-butyldiaziridinone, 010402 general chemistry, 01 natural sciences, Combinatorial chemistry, Catalysis, 0104 chemical sciences, Surfaces, Coatings and Films, Electronic, Optical and Magnetic Materials, Ruthenium, chemistry.chemical_compound, chemistry, Octahedron, Reagent, Materials Chemistry, Ceramics and Composites, Amination, Carbon monoxide
Abstract

Application of an oxidative amination reagent (di-tert-butyldiaziridinone) to the Ru3(CO)12-catalyzed ortho-selective CAr–H amination reaction is described. This strategy shows good functional group compatibility with various phenyl-substituted N-heterocycles, including biologically active substrates, thus providing synthetic potential for this methodology. Mechanistic studies showed that the reaction process involves an octahedral ruthenium species, and the carbon monoxide ligand plays a crucial role in the C–H activation.

Published
2019

Catalog

Books, media, physical & digital resources
See catalog results