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Start Over Author "Fonslow, Bryan R." Journal chemical reviews
2 results on '"Fonslow, Bryan R."'

2. Protein Analysis by Shotgun/Bottom-up Proteomics.

Author

Yaoyang Zhang, Fonslow, Bryan R., Bing Shan, Baek, Moon-Chang, and Yates III, John R.

Subjects
*PROTEOMICS, *PROTEIN analysis, *TWO-dimensional electrophoresis, *POLYACRYLAMIDE gel electrophoresis, *CHROMATOGRAPHIC analysis, *POST-translational modification, *MASS spectrometry
Abstract

The article discusses the technique of shotgun/ bottom-up proteomics for the analysis of protein. It states that bottom-up process characterizes protein by analyzing the peptides released from the protein through proteolysis. It discusses several techniques related to shotgun proteomics which include two dimensional polyacrylamide gel electrophoresis (20-PAGE), chromatographic methods and post-translational modification (PTM) analysis by Mass Spectrometry.

Published
2013
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