Search

Your search keyword '"Cheng, Jin‐Pei"' showing total 21 results
Start Over Author "Cheng, Jin‐Pei" Journal chemistry - a european journal
21 results on '"Cheng, Jin‐Pei"'

1. Hydroxylamine‐Mediated C(sp2)−H Trifluoromethylation of Terminal Alkenes.

Author

Zhao, Xiao, Zhong, Bing, Dong, Likun, Zhang, Yu‐Shan, Luo, Hai‐Tian, Yang, Jin‐Dong, and Cheng, Jin‐Pei

Subjects
ALKENES, RADICALS (Chemistry), FUNCTIONAL groups, ORGANIC compounds
Abstract

Introduction of the trifluoromethyl (CF3) group into organic compounds has garnered substantial interest because of its significant role in pharmaceuticals and agrochemicals. Here, we report a hydroxylamine‐mediated radical process for C(sp2)−H trifluoromethylation of terminal alkenes. The reaction shows good reactivity, impressive E/Z selectivity (up to >20 : 1), and broad functional group compatibility. Expansion of this approach to perfluoroalkylation and late‐stage trifluoromethylation of bioactive molecules demonstrates its promising application potential. Mechanistic studies suggest that the reaction follows a radical addition and subsequent elimination pathway. [ABSTRACT FROM AUTHOR]

Published
2024
Full Text
View/download PDF

17. Primary-Tertiary Diamine/Brønsted Acid Catalyzed C-C Coupling between para-Vinylanilines and Aldehydes.

Author

Cui, Lingyun, Zhu, Yunbo, Luo, Sanzhong, and Cheng, Jin‐Pei

Subjects
ANILINE, ENAMINES, INTERMEDIATES (Chemistry), AROMATIC compounds, ORGANOCATALYSIS, VINYLATION, ALDEHYDES, COUPLING reactions (Chemistry)
Abstract

Aromatic enamines: para‐Vinylanilines were identified as unique nucleophiles, closely resembling enamines, to undergo CC coupling with aldehydes catalyzed by a simple primary–tertiary diamine/Brønsted acid. The resulting bis(allylic) adducts, which have potential as functional materials, were obtained in high yields under rather mild conditions (see scheme). [ABSTRACT FROM AUTHOR]

Published
2013
Full Text
View/download PDF

21. Asymmetric Binary‐Acid Catalysis with InBr3in the Inverse‐Electron‐Demanding Hetero‐Diels–Alder Reaction of Mono‐ and Bis‐Substituted Cyclopentadienes: Remote Fluoro‐Effect on Stereocontrol

Author

Lv, Jian, Zhang, Long, Hu, Shenshen, Cheng, Jin‐Pei, and Luo, Sanzhong

Abstract

Remote F effect: Unprecedented hetero‐Diels–Alder reactions of mono‐ and bis‐substituted cyclopentadienes have been realized by an asymmetric binary‐acid catalyst that synergistically combines a chiral phosphoric acid 1 h/InBr3with good periselectivity, high regioselectivity, and excellent stereoselectivity. Substituent mapping of the chiral phosphoric acid indicates a dramatic remote ortho‐fluoro effect on the stereocontrol (see scheme).

Published
2012
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results